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Highlights of 10 years of immunology in Nature Reviews Immunology

  1. Author:
    Medzhitov, R.
    Shevach, E. M.
    Trinchieri, G.
    Mellor, A. L.
    Munn, D. H.
    Gordon, S.
    Libby, P.
    Hansson, G. K.
    Shortman, K.
    Dong, C.
    Gabrilovich, D.
    Gabrysova, L.
    Howes, A.
    O'Garra, A.

  2. Author Address

    [Medzhitov, R] Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06510 USA. [Medzhitov, R] Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06510 USA. [Shevach, EM] NIAID, Immunol Lab, NIH, Bethesda, MD 20892 USA. [Trinchieri, G] NCI, Canc & Inflammat Program, Ctr Canc Res, Frederick, MD 21702 USA. [Mellor, AL; Munn, DH] Georgia Hlth Sci Univ, Immunotherapy Ctr, Augusta, GA 30912 USA. [Mellor, AL; Munn, DH] Georgia Hlth Sci Univ, Ctr Canc, Augusta, GA 30912 USA. [Gordon, S] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England. [Libby, P] Brigham & Womens Hosp, Dept Med, Boston, MA 02115 USA. [Libby, P] Harvard Univ, Sch Med, Boston, MA 02115 USA. [Hansson, GK] Karolinska Inst, Karolinska Univ Hosp, Ctr Mol Med, Dept Med, SE-17176 Stockholm, Sweden. [Shortman, K] Walter & Eliza Hall Inst Med Res, Melbourne, Vic, Australia. [Dong, C] Univ Texas MD Anderson Canc Ctr, Dept Immunol, Houston, TX 77030 USA. [Dong, C] Univ Texas MD Anderson Canc Ctr, Ctr Inflammat & Canc, Houston, TX 77030 USA. [Gabrilovich, D] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33647 USA. [Gabrysova, L; Howes, A; O'Garra, A] MRC Natl Inst Med Res, Div Immunoregulat, London, England.;Medzhitov, R (reprint author), Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06510 USA;ruslan.medzhitov@yale.edu EShevach@niaid.nih.gov trinchig@niaid.nih.gov amellor@georgiahealth.edu dmunn@georgiahealth.edu siamon.gordon@path.ox.ac.uk plibby@rics.bwh.harvard.edu shortman@wehi.edu.au CDong@mdanderson.org Dmitry.Gabrilovich@moffitt.org aogarra@nimr.mrc.ac.uk
    1. Year: 2011
    2. Date: Oct
  2. Journal: Nature Reviews Immunology
    1. 11
    2. 10
    3. Pages: 693-702
  4. Type of Article: Article
  5. ISSN: 1474-1733
  1. Abstract:

    As Nature Reviews Immunology reaches its 10(th) anniversary, the authors of one of the top-cited articles from each year take a trip down memory lane. We've asked them to look back on the state of research at the time their Review was published, to consider why the article has had the impact it has and to discuss the future directions of their field. This Viewpoint article provides an interesting snapshot of some of the fundamental advances in immunology over the past 10 years. Highlights include our improved understanding of Toll-like receptor signalling, and of immune regulation mediated by regulatory T cells, indoleamine 2,3-dioxygenase, myeloid-derived suppressor cells and interleukin-10. The complexities in the development and heterogeneity of macrophages, dendritic cells and T helper cells continue to engage immunologists, as do the immune processes involved in diseases such as atherosclerosis. We look forward to what the next 10 years of immunology research may bring.

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External Sources

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  2. DOI: 10.1038/nri3063
  3. View record in Web of Science®
  4. WOS: 000295156600016

Library Notes

  1. Fiscal Year: FY2011-2012
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