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A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/beta-catenin pathway

  1. Author:
    Dogan, Aysegul
    Demirci, Selarni
    Apdik, Huseyin
    Bayrak, Omer Faruk
    Gulluoglu, Sukru
    Tuysuz, Emre Can
    Gusev, Oleg
    Rizvanov, Albert A.
    Nikerel, Emrah
    Sahin, Fikrettin

  2. Author Address

    Yeditepe Univ, Fac Engn, Dept Genet & Bioengn, Kayisdagi Cad 26 Agustos Yerlesimi, TR-34755 Istanbul, Turkey.NIH, CDBL, Natl Canc Inst, Frederick, MD USA.NIH, NHLBI, Bldg 10, Bethesda, MD 20892 USA.Yeditepe Univ Med Sch Inonu Mah, Dept Med Genet, Kayisdagi Cad 26 Agustos Yerlesimi, TR-34755 Istanbul, Turkey.Kazan Fed Univ, Inst Fundamental Med & Biol, Kazan, Russia.Riken Innovat Ctr, Yokohama, Kanagawa, Japan.
    1. Year: 2017
    2. Date: Apr
    3. Epub Date: 2017 Jan 19
  2. Journal: METABOLISM-CLINICAL AND EXPERIMENTAL
  3. W B SAUNDERS CO-ELSEVIER INC,
    1. 69
    2. Pages: 130-142
  5. Type of Article: Article
  6. ISSN: 0026-0495
  1. Abstract:

    Obesity is a worldwide medical problem resulting in serious morbidity and mortality involving differentiation of pre-adipocytes into mature adipocytes (adipogenesis). Boron treatment has been reported to be associated with weight reduction in experimental animals; however, its effects on pre-adipocyte differentiation and anti-adipogenic molecular mechanisms are unknown.

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  1. Keywords:

External Sources

  1. View Full Text
  2. DOI: 10.1016/j.metabol.2017.01.021
  3. PMID: 28285642
  4. View record in Web of Science®
  5. WOS: 000397697800014

Library Notes

  1. Fiscal Year: FY2016-2017
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