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Quantitation of Surface Coating on Nanoparticles Using Thermogravimetric Analysis

  1. Author:
    Dongargaonkar, Alpana
    Clogston, Jeffrey

  2. Author Address

    Cancer Research Technology Program, Nanotechnology Characterization Laboratory, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, P.O. Box B, Frederick, MD, 21702, USA., Cancer Research Technology Program, Nanotechnology Characterization Laboratory, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, P.O. Box B, Frederick, MD, 21702, USA. Jeffrey.Clogston@fnlcr.nih.gov.,
    1. Year: 2018
  2. Journal: Methods in molecular biology (Clifton, N.J.)
    1. 1682
    2. Pages: 57-63
  4. Type of Article: Article
  1. Abstract:

    Nanoparticles are critical components in nanomedicine and nanotherapeutic applications. Some nanoparticles, such as metallic nanoparticles, consist of a surface coating or surface modification to aid in its dispersion and stability. This surface coating may affect the behavior of nanoparticles in a biological environment, thus it is important to measure. Thermogravimetric analysis (TGA) can be used to determine the amount of coating on the surface of the nanoparticle. TGA experiments run under inert atmosphere can also be used to determine residual metal content present in the sample. In this chapter, the TGA technique and experimental method are described.

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  2. DOI: 10.1007/978-1-4939-7352-1_6
  3. PMID: 29039093

Library Notes

  1. Fiscal Year: FY2017-2018
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