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Outdoor air pollution and mosaic loss of chromosome Y in older men from the Cardiovascular Health Study

  1. Author:
    Wong, Jason Y. Y.
    Margolis, Helene G.
    Machiela, Mitchell
    Zhou, Weiyin
    Odden, Michelle C.
    Psaty, Bruce M.
    Robbins, John
    Jones, Rena R.
    Rotter, Jerome I.
    Chanock, Stephen J.
    Rothman, Nathaniel
    Lan, Qing
    Lee, Jennifer S.

  2. Author Address

    NCI, Div Canc Epidemiol & Genet, NIH, Rockville, MD USA.Univ Calif Davis, Sch Med, Dept Internal Med, Davis, CA 95616 USA.Leidos Biomed Res Inc, NCI, Canc Genom Res Lab, Div Canc Epidemiol & Genet, Bethesda, MD USA.Oregon State Univ, Sch Biol & Populat Hlth Sci, Corvallis, OR 97331 USA.Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA 98195 USA.Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.Univ Washington, Dept Hlth Serv, Seattle, WA 98195 USA.Kaiser Permanente Washington Hlth Res Inst, Seattle, WA USA.Harbor UCLA Med, Inst Translat Genom & Populat Sci, Torrance, CA USA.Harbor UCLA Med, Los Angeles BioMed Res Inst, Dept Pediat, Torrance, CA USA.Stanford Univ, Dept Med, Div Endocrinol Gerontol & Metab, Stanford, CA 94305 USA.Stanford Univ, Sch Med, Dept Hlth Res & Policy, Div Epidemiol, Stanford, CA 94305 USA.Palo Alto Hlth Care Syst, Med Serv, Vet Affairs, Palo Alto, CA USA.
    1. Year: 2018
    2. Date: Jul
  2. Journal: ENVIRONMENT INTERNATIONAL
  3. PERGAMON-ELSEVIER SCIENCE LTD,
    1. 116
    2. Pages: 239-247
  5. Type of Article: Article
  6. ISSN: 0160-4120
  1. Abstract:

    Background: Mosaic loss of chromosome Y (mLOY) can occur in a fraction of cells as men age, which is potentially linked to increased mortality risk. Smoking is related to mLOY; however, the contribution of air pollution is unclear.

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External Sources

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  2. DOI: 10.1016/j.envint.2018.04.030
  3. PMID: 29698900
  4. View record in Web of Science®
  5. WOS: 000432745000027

Library Notes

  1. Fiscal Year: FY2017-2018
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