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8-Day Inpatient Directly Observed Therapy for ART Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support

  1. Author:
    Winchester, Nicole E
    Maldarelli, Frank
    Mejia,Yolanda
    Dee,Nicola
    Dewar,Robin
    Laidlaw, Elizabeth
    Kuriakose,Safia
    Stoll, Pamela
    Proschan, Michael
    Lane, H Clifford
    Pau, Alice K

  2. Author Address

    National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, Maryland, USA., National Cancer Institute, NIH, Frederick, Maryland, USA., Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, Maryland, USA., Clinical Center, NIH, Bethesda, Maryland, USA.,
    1. Year: 2020
    2. Date: MAR 15
    3. Epub Date: 2019 07 11
  2. Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
    1. 70
    2. 6
    3. Pages: 1222-1225
  4. Type of Article: Article
  5. ISSN: 1058-4838
  1. Abstract:

    Among 20 highly treatment experienced people with HIV with extensive antiretroviral drug resistance and high levels of self-reported adherence, an inpatient 8-day directly observed therapy confirmed nonadherence as the major cause of virologic failure for 9/20 (45%) participants, preventing unnecessary regimen changes that could jeopardize future treatment options. Published by Oxford University Press for the Infectious Diseases Society of America 2019. This work is written by (a) US Government employee(s) and is in the public domain in the US.

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External Sources

  1. View Full Text
  2. DOI: 10.1093/cid/ciz590
  3. PMID: 31298273
  4. View record in Web of Science®
  5. WOS: 000518549900034
  6. PII : 5531519

Library Notes

  1. Fiscal Year: FY2018-2019
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