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Emergence of Kaposi's Sarcoma Herpesvirus-Associated Complications Following Corticosteroid Use in TB-IRIS

  1. Author:
    Manion, Maura [ORCID]
    Uldrick, Thomas
    Polizzotto, Mark N
    Sheikh, Virginia
    Roby, Gregg
    Lurain, Kathryn
    Metzger, Dorinda
    Mican, JoAnn M
    Pau, Alice
    Lisco, Andrea
    Laidlaw, Elizabeth
    Hammoud, Dima A
    Whitby,Denise
    Yarchoan, Robert
    Sereti, Irini

  2. Author Address

    National Institute of Allergy and Infectious Disease, National Institutes of Health (NIH), Bethesda, Maryland., National Cancer Institute, NIH, Bethesda, Maryland., Center for Infectious Diseases Imaging, NIH, Bethesda, Maryland., Viral Oncology Section, AIDS and Cancer Virus Program, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland.,
    1. Year: 2018
    2. Date: Oct
    3. Epub Date: 2018 10 12
  2. Journal: Open forum infectious diseases
    1. 5
    2. 10
    3. Pages: ofy217
  4. Type of Article: Article
  5. Article Number: ofy217
  6. ISSN: 2328-8957
  1. Abstract:

    Corticosteroid use was associated with development of Kaposi's sarcoma or multicentric Castleman disease in 3 patients with mycobacterial immune reconstitution inflammatory syndrome (IRIS) treated with corticosteroids. Monitoring for development of Kaposi's sarcoma and alternative treatment may be beneficial for patients with IRIS, especially in the presence of preexisting co-infection with Kaposi's sarcoma-associated herpesvirus.

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  1. Keywords:

External Sources

  1. View Full Text
  2. DOI: 10.1093/ofid/ofy217
  3. PMID: 30568973
  4. PMCID: PMC6182308
  5. View record in Web of Science®
  6. WOS: 000450291600008
  7. PII : ofy217

Library Notes

  1. Fiscal Year: FY2018-2019
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