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Towards fair decentralized benchmarking of healthcare AI algorithms with the Federated Tumor Segmentation (FeTS) challenge

  1. Author:
    Zenk, Maximilian [ORCID]
    Baid, Ujjwal [ORCID]
    Pati, Sarthak [ORCID]
    Linardos, Akis
    Edwards, Brandon [ORCID]
    Sheller, Micah [ORCID]
    Foley, Patrick [ORCID]
    Aristizabal, Alejandro
    Zimmerer, David
    Gruzdev, Alexey
    Martin, Jason [ORCID]
    Shinohara, Russell T
    Reinke, Annika [ORCID]
    Isensee, Fabian
    Parampottupadam, Santhosh [ORCID]
    Parekh, Kaushal
    Floca, Ralf [ORCID]
    Kassem, Hasan [ORCID]
    Baheti, Bhakti
    Thakur, Siddhesh
    Chung, Verena [ORCID]
    Kushibar, Kaisar [ORCID]
    Lekadir, Karim
    Jiang, Meirui [ORCID]
    Yin, Youtan
    Yang, Hongzheng
    Liu, Quande
    Chen, Cheng [ORCID]
    Dou, Qi
    Heng, Pheng-Ann [ORCID]
    Zhang, Xiaofan
    Zhang, Shaoting [ORCID]
    Khan, Muhammad Irfan
    Azeem, Mohammad Ayyaz
    Jafaritadi, Mojtaba [ORCID]
    Alhoniemi, Esa
    Kontio, Elina [ORCID]
    Khan, Suleiman A
    Mächler, Leon
    Ezhov, Ivan [ORCID]
    Kofler, Florian [ORCID]
    Shit, Suprosanna [ORCID]
    Paetzold, Johannes C
    Loehr, Timo
    Wiestler, Benedikt
    Peiris, Himashi
    Pawar, Kamlesh
    Zhong, Shenjun [ORCID]
    Chen, Zhaolin [ORCID]
    Hayat, Munawar
    Egan, Gary
    Harandi, Mehrtash
    Isik Polat, Ece [ORCID]
    Polat, Gorkem [ORCID]
    Kocyigit, Altan [ORCID]
    Temizel, Alptekin [ORCID]
    Tuladhar, Anup [ORCID]
    Tyagi, Lakshay
    Souza, Raissa
    Forkert, Nils D [ORCID]
    Mouches, Pauline
    Wilms, Matthias [ORCID]
    Shambhat, Vishruth
    Maurya, Akansh
    Danannavar, Shubham Subhas
    Kalla, Rohit
    Anand, Vikas Kumar
    Krishnamurthi, Ganapathy
    Nalawade, Sahil
    Ganesh, Chandan
    Wagner, Ben [ORCID]
    Reddy, Divya
    Das, Yudhajit
    Yu, Fang F
    Fei, Baowei
    Madhuranthakam, Ananth J
    Maldjian, Joseph
    Singh, Gaurav
    Ren, Jianxun
    Zhang, Wei
    An, Ning [ORCID]
    Hu, Qingyu
    Zhang, Youjia
    Zhou, Ying
    Siomos, Vasilis
    Tarroni, Giacomo
    Passerrat-Palmbach, Jonathan [ORCID]
    Rawat, Ambrish
    Zizzo, Giulio
    Kadhe, Swanand Ravindra
    Epperlein, Jonathan P
    Braghin, Stefano [ORCID]
    Wang, Yuan
    Kanagavelu, Renuga
    Wei, Qingsong
    Yang, Yechao
    Liu, Yong [ORCID]
    Kotowski, Krzysztof
    Adamski, Szymon
    Machura, Bartosz [ORCID]
    Malara, Wojciech
    Zarudzki, Lukasz
    Nalepa, Jakub [ORCID]
    Shi, Yaying [ORCID]
    Gao, Hongjian
    Avestimehr, Salman
    Yan, Yonghong
    Akbar, Agus S [ORCID]
    Kondrateva, Ekaterina
    Yang, Hua
    Li, Zhaopei
    Wu, Hung-Yu
    Roth, Johannes
    Saueressig, Camillo
    Milesi, Alexandre
    Nguyen, Quoc D
    Gruenhagen, Nathan J
    Huang, Tsung-Ming
    Ma, Jun [ORCID]
    Singh, Har Shwinder H
    Pan, Nai-Yu
    Zhang, Dingwen
    Zeineldin, Ramy A
    Futrega, Michal
    Yuan, Yading
    Conte, Gian Marco [ORCID]
    Feng, Xue
    Pham, Quan D
    Xia, Yong [ORCID]
    Jiang, Zhifan [ORCID]
    Luu, Huan Minh
    Dobko, Mariia
    Carré, Alexandre
    Tuchinov, Bair
    Mohy-Ud-Din, Hassan
    Alam, Saruar
    Singh, Anup
    Shah, Nameeta [ORCID]
    Wang, Weichung
    Sako, Chiharu [ORCID]
    Bilello, Michel
    Ghodasara, Satyam [ORCID]
    Mohan, Suyash [ORCID]
    Davatzikos, Christos [ORCID]
    Calabrese, Evan [ORCID]
    Rudie, Jeffrey
    Villanueva-Meyer, Javier
    Cha, Soonmee
    Hess, Christopher [ORCID]
    Mongan, John
    Ingalhalikar, Madhura
    Jadhav, Manali [ORCID]
    Pandey, Umang [ORCID]
    Saini, Jitender
    Huang, Raymond Y
    Chang, Ken
    To, Minh-Son
    Bhardwaj, Sargam
    Chong, Chee
    Agzarian, Marc [ORCID]
    Kozubek, Michal [ORCID]
    Lux, Filip [ORCID]
    Michálek, Jan [ORCID]
    Matula, Petr [ORCID]
    Ker Kovský, Miloš [ORCID]
    Kopr Ivová, Tereza [ORCID]
    Dostál, Marek [ORCID]
    Vybíhal, Václav [ORCID]
    Pinho, Marco C
    Holcomb, James
    Metz, Marie [ORCID]
    Jain, Rajan [ORCID]
    Lee, Matthew D [ORCID]
    Lui, Yvonne W [ORCID]
    Tiwari, Pallavi
    Verma, Ruchika
    Bareja, Rohan
    Yadav, Ipsa
    Chen, Jonathan [ORCID]
    Kumar, Neeraj
    Gusev, Yuriy [ORCID]
    Bhuvaneshwar, Krithika [ORCID]
    Sayah, Anousheh [ORCID]
    Bencheqroun, Camelia
    Belouali, Anas [ORCID]
    Madhavan, Subha
    Colen, Rivka R
    Kotrotsou, Aikaterini
    Vollmuth, Philipp
    Brugnara, Gianluca [ORCID]
    Preetha, Chandrakanth J [ORCID]
    Sahm, Felix [ORCID]
    Bendszus, Martin
    Wick, Wolfgang [ORCID]
    Mahajan, Abhishek [ORCID]
    Balaña, Carmen [ORCID]
    Capellades, Jaume
    Puig, Josep
    Choi, Yoon Seong [ORCID]
    Lee, Seung-Koo [ORCID]
    Chang, Jong Hee [ORCID]
    Ahn, Sung Soo [ORCID]
    Shaykh, Hassan F [ORCID]
    Herrera-Trujillo, Alejandro [ORCID]
    Trujillo, Maria
    Escobar, William
    Abello, Ana
    Bernal, Jose [ORCID]
    Gómez, Jhon
    LaMontagne, Pamela [ORCID]
    Marcus, Daniel S
    Milchenko, Mikhail [ORCID]
    Nazeri, Arash [ORCID]
    Landman, Bennett [ORCID]
    Ramadass, Karthik [ORCID]
    Xu, Kaiwen [ORCID]
    Chotai, Silky [ORCID]
    Chambless, Lola B
    Mistry, Akshitkumar
    Thompson, Reid C
    Srinivasan, Ashok
    Bapuraj, J Rajiv [ORCID]
    Rao, Arvind
    Wang, Nicholas [ORCID]
    Yoshiaki, Ota
    Moritani, Toshio
    Turk, Sevcan
    Lee, Joonsang
    Prabhudesai, Snehal
    Garrett, John [ORCID]
    Larson, Matthew
    Jeraj, Robert
    Li, Hongwei
    Weiss, Tobias [ORCID]
    Weller, Michael [ORCID]
    Bink, Andrea [ORCID]
    Pouymayou, Bertrand [ORCID]
    Sharma, Sonam
    Tseng, Tzu-Chi
    Adabi, Saba
    Xavier Falcão, Alexandre [ORCID]
    Martins, Samuel B [ORCID]
    Teixeira, Bernardo C A [ORCID]
    Sprenger, Flávia [ORCID]
    Menotti, David [ORCID]
    Lucio, Diego R
    Niclou, Simone P [ORCID]
    Keunen, Olivier [ORCID]
    Hau, Ann-Christin [ORCID]
    Pelaez, Enrique [ORCID]
    Franco-Maldonado, Heydy [ORCID]
    Loayza, Francis [ORCID]
    Quevedo, Sebastian [ORCID]
    McKinley, Richard [ORCID]
    Slotboom, Johannes [ORCID]
    Radojewski, Piotr
    Meier, Raphael
    Wiest, Roland [ORCID]
    Trenkler, Johannes [ORCID]
    Pichler, Josef
    Necker, Georg
    Haunschmidt, Andreas [ORCID]
    Meckel, Stephan [ORCID]
    Guevara, Pamela [ORCID]
    Torche, Esteban
    Mendoza, Cristobal [ORCID]
    Vera, Franco [ORCID]
    Ríos, Elvis [ORCID]
    López, Eduardo [ORCID]
    Velastin, Sergio A
    Choi, Joseph
    Baek, Stephen
    Kim, Yusung
    Ismael, Heba
    Allen, Bryan [ORCID]
    Buatti, John M [ORCID]
    Zampakis, Peter [ORCID]
    Panagiotopoulos, Vasileios [ORCID]
    Tsiganos, Panagiotis [ORCID]
    Alexiou, Sotiris
    Haliassos, Ilias [ORCID]
    Zacharaki, Evangelia I [ORCID]
    Moustakas, Konstantinos [ORCID]
    Kalogeropoulou, Christina [ORCID]
    Kardamakis, Dimitrios M
    Luo, Bing
    Poisson, Laila M [ORCID]
    Wen, Ning
    Vallières, Martin [ORCID]
    Loutfi, Mahdi Ait Lhaj [ORCID]
    Fortin, David
    Lepage, Martin [ORCID]
    Morón, Fanny [ORCID]
    Mandel, Jacob [ORCID]
    Shukla, Gaurav
    Liem, Spencer
    Alexandre, Gregory S
    Lombardo, Joseph
    Palmer, Joshua D [ORCID]
    Flanders, Adam E
    Dicker, Adam P [ORCID]
    Ogbole, Godwin
    Oyekunle, Dotun [ORCID]
    Odafe-Oyibotha, Olubunmi
    Osobu, Babatunde
    Shu'aibu Hikima, Mustapha
    Soneye, Mayowa
    Dako, Farouk
    Dorcas, Adeleye
    Murcia, Derrick
    Fu, Eric
    Haas, Rourke
    Thompson, John A [ORCID]
    Ormond, David Ryan [ORCID]
    Currie, Stuart [ORCID]
    Fatania, Kavi [ORCID]
    Frood, Russell [ORCID]
    Simpson, Amber L [ORCID]
    Peoples, Jacob J [ORCID]
    Hu, Ricky
    Cutler, Danielle [ORCID]
    Moraes, Fabio Y
    Tran, Anh [ORCID]
    Hamghalam, Mohammad
    Boss, Michael A [ORCID]
    Gimpel, James [ORCID]
    Kattil Veettil, Deepak [ORCID]
    Schmidt, Kendall
    Cimino, Lisa
    Price, Cynthia
    Bialecki, Brian [ORCID]
    Marella, Sailaja
    Apgar, Charles
    Jakab, Andras [ORCID]
    Weber, Marc-André [ORCID]
    Colak, Errol
    Kleesiek, Jens [ORCID]
    Freymann,John
    Kirby,Justin
    Maier-Hein, Lena
    Albrecht, Jake
    Mattson, Peter [ORCID]
    Karargyris, Alexandros [ORCID]
    Shah, Prashant
    Menze, Bjoern [ORCID]
    Maier-Hein, Klaus
    Bakas, Spyridon [ORCID]

  2. Author Address

    German Cancer Research Center (DKFZ) Heidelberg, Division of Medical Image Computing, Heidelberg, Germany., Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany., Center for Federated Learning in Medicine, Indiana University, Indianapolis, IN, USA., Division of Computational Pathology, Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Medical Research Group, MLCommons, San Francisco, CA, USA., Intel Corporation, Santa Clara, CA, USA., Factored, Palo Alto, CA, USA., Center for AI and Data Science for Integrated Diagnostics (AI2D), University of Pennsylvania, Philadelphia, PA, USA., Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Penn Statistics in Imaging and Visualization Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., German Cancer Research Center (DKFZ) Heidelberg, Division of Intelligent Medical Systems, Heidelberg, Germany., Helmholtz Imaging, German Cancer Research Center (DKFZ), Heidelberg, Germany., Sage Bionetworks, Seattle, WA, USA., Department of Mathematics and Computer Science, Universitat de Barcelona, Barcelona, Spain., Department of Mathematics and Computer Science, Universitat de Barcelona, Artificial Intelligence in Medicine Lab (BCN-AIM), Barcelona, Spain., Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China., Department of Computer Science and Technology, Zhejiang University, Hangzhou, China., Department of Computer Science and Engineering, Beihang University, Beijing, China., Shanghai Jiao Tong University, Shanghai, China., Shanghai Artificial Intelligence Laboratory, Shanghai, China., School of Data Engineering and AI Technologies, Turku University of Applied Sciences, Turku, Finland., Riphah International University, Islamabad, Pakistan., Department of Radiology, Stanford University, Stanford, CA, USA., University of Helsinki, Helsinki, Finland., École Normale Supérieure Paris, France., Department of Informatics, Technical University of Munich, Munich, Germany., TranslaTUM - Central Institute for Translational Cancer Research, Technical University of Munich, Munich, Germany., Department of Diagnostic and Interventional Neuroradiology, School of Medicine and Health, Technical University of Munich, Munich, Germany., Department of Quantitative Biomedicine, University of Zurich, Zurich, Switzerland., ITERM Institute Helmholtz Zentrum Muenchen, Neuherberg, Germany., Department of Radiology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Monash Biomedical Imaging, Monash University, Melbourne, VIC, Australia., Department of Electrical and Computer Systems Engineering, Faculty of Engineering, Monash University, Melbourne, VIC, Australia., Department of Data Science and AI, Faculty of Information Technology, Monash University, Melbourne, VIC, Australia., School of Psychological Sciences, Monash University, Melbourne, VIC, Australia., National Imaging Facility, St Lucia, QLD, Australia., Graduate School of Informatics, Middle East Technical University, Ankara, Turkey., Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada., Department of Chemical Engineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India., Biomedical Engineering Program, University of Calgary, Calgary, AB, Canada., Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada., Department of Engineering Design, IIT Madras, Chennai, India., Robert Bosch Center of Data Science and AI, IIT Madras, Chennai, India., University of Texas Southwestern Medical Center, Dallas, TX, USA., Department of Bioengineering, University of Texas at Dallas, Dallas, TX, USA., Indian Institute of Information Technology Vadodara, Gandhinagar, India., Changping Laboratory, Beijing, China., School of Electrical and Computer Engineering, Cornell University, Ithaca, NY, USA., City St George 39;s, University of London, London, UK., Imperial College London, London, UK., IBM Research, Dublin, Ireland., Institute of High Performance Computing (IHPC), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Graylight Imaging, Gliwice, Poland., Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice, Poland., Silesian University of Technology, Gliwice, Poland., University of North Carolina at Charlotte, Charlotte, NC, USA., Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., University of Southern California, Los Angeles, CA, USA., Universitas Islam Nahdlatul Ulama Jepara, Jepara, Indonesia., Skolkovo Institute of Science and Technology, Moscow, Russia., Fujian Normal University, Fuzhou, China., Fuzhou University, Fuzhou, China., National Tsing Hua University, Hsinchu, Taiwan., ScaDS.AI, Dresden, Germany., Brown University, Providence, RI, USA., NVIDIA, Santa Clara, CA, USA., EPITA, Le Kremlin-Bicêtre, France., Medical College of Wiconsin, Milwaukee, WI, USA., Department of Mathematics, National Taiwan Normal University, Taipei, Taiwan., Nanjing University of Science and Technology, Nanjing, China., Hong Kong University of Science and Technology, Hong Kong, Hong Kong Special Administrative Region of China, China., National Taiwan University of Science and Technology, Taipei, Taiwan., School of Automation, Northwestern Polytechnical University, Xi 39;an, China., Institute for Anthropomatics and Robotics, Karlsruhe Institute of Technology, Karlsruhe, Germany., Department of Radiation Oncology, Columbia University Irving Medical Center, New York, NY, USA., Columbia University Data Science Institute, New York, NY, USA., Department of Radiology, Mayo Clinic, Rochester, MN, USA., University of Virginia, Charlottesville, VA, USA., VinBrain, Hanoi, Vietnam., School of Computer Science and Engineering, Northwestern Polytechnical University, Xi'an, China., Children's National Hospital, Washington, DC, USA., MRI Lab, KAIST, Daejeon, Korea., Ukrainian Catholic University, Lviv, Ukraine., Gustave Roussy Cancer Campus, Villejuif, France., Novosibirsk State University, Novosibirsk, Russia., Department of Electrical Engineering, Syed Babar Ali School of Science and Engineering, LUMS, Lahore, Pakistan., University of Bergen, Bergen, Norway., Indian Institute of Technology, Delhi, India., Mazumdar Shaw Medical Foundation, Bengaluru, India., Institute of Applied Mathematical Sciences, National Taiwan University, Taipei, Taiwan., Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA., Symbiosis Center for Medical Image Analysis, Symbiosis International University, Pune, India., Department of Neuroimaging and interventional Radiology, National Institute of Mental Health and Neurosciences, Bangalore, India., Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA., College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia., South Australia Medical Imaging, Flinders Medical Centre, Bedford Park, SA, Australia., Centre for Biomedical Image Analysis, Faculty of Informatics, Masaryk University, Brno, Czech Republic., Department of Radiology and Nuclear Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic., Department of Biophysics, Faculty of Medicine, Masaryk University, Brno, Czech Republic., Department of Neurosurgery, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic., Department of Neuroradiology, Klinikum rechts der Isar, Munich, Germany., Department of Radiology, NYU Grossman School of Medicine, New York, NY, USA., Department of Neurosurgery, NYU Grossman School of Medicine, New York, NY, USA., Department of Radiology, Biomedical Engineering, Medical Physics, University of Wisconsin School of Medicine & Public Health, Madison, WI, USA., William S. Middleton Memorial Veterans Affairs (VA), Madison, WI, USA., Case Western Reserve University, Cleveland, OH, USA., Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA., University of Alberta, Edmonton, AB, Canada., Alberta Machine Intelligence Institute, Edmonton, AB, Canada., Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Innovation Center for Biomedical Informatics (ICBI), Georgetown University, Washington, DC, USA., Division of Neuroradiology & Neurointerventional Radiology, MedStar Georgetown University Hospital, Department of Radiology, Washington, DC, USA., Department of Radiology, Neuroradiology Division, University of Pittsburgh, Pittsburgh, PA, USA., Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Division for Computational Radiology & Clinical AI, University Hospital Bonn, Bonn, Germany., Faculty of Medicine, University of Bonn, Bonn, Germany., Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany., Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany., Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK) within the German Cancer Research Center (DKFZ), Heidelberg, Germany., Neurology Clinic, Heidelberg University Hospital, Heidelberg, Germany., Department of Radiodiagnosis and Imaging, Tata Memorial Centre, Tata Memorial Hospital, HBNI, Mumbai, India., Department of Imaging, The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, UK., Catalan Institute of Oncology, Badalona, Spain., Consorci MAR Parc de Salut de Barcelona, Catalonia, Spain., Radiology Department CDI and IDIBAPS, Hospital Clinic of Barcelona, Barcelona, Spain., National University of Singapore, Yong Loo Lin School of Medicine, Singapore, Singapore., Yonsei University College of Medicine, Seoul, Korea., University of Alabama in Birmingham, Birmingham, AL, USA., Clínica Imbanaco QuirónSalud, Cali, Colombia., Universidad del Valle, Cali, Colombia., The University of Edinburgh, Edinburgh, UK., German Centre for Neurodegenerative Diseases (DZNE), Magdeburg, Germany., Institute for cognitive neurology and dementia research (IKND), Magdeburg, Germany., Department of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Neuroimaging Informatics and Analysis Center, Washington University in St. Louis, St. Louis, MO, USA., Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, USA., Department of Computer Science, Vanderbilt University, Nashville, TN, USA., Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, TN, USA., Department of Neuroradiology, University of Michigan, Ann Arbor, MI, USA., Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Department of Radiology, UW Madison School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Department of Medical Physics, UW Madison School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., Department of Neurology and Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Department of Neuroradiology and Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland., Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Institute of Computing, University of Campinas, Campinas, São Paulo, Brazil., Federal Institute of Education, Science, and Technology of São Paulo, Araraquara, São Paulo, Brazil., Instituto de Neurologia de Curitiba, Curitiba, Paraná, Brazil., Federal University of Parana, Curitiba, Paraná, Brazil., Department of Informatics, Federal University of Parana, Curitiba, Paraná, Brazil., NORLUX Neuro-Oncology Laboratory, Luxembourg Institute of Health, Luxembourg, Luxembourg., Faculty of Science, Technology and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., Brain Imaging and Neuro Epidemiology Group, Luxembourg Institute of Health, Luxembourg, Luxembourg., Goethe University, University Hospital, Dr. Senckenberg Institute of Neurooncology, Frankfurt am Main, Germany., Escuela Superior Politecnica del Litoral, Guayaquil, Guayas, Ecuador., Sociedad de Lucha Contral el Cancer - SOLCA, Guayaquil, Ecuador., Universidad Cat 243;lica de Cuenca, Cuenca, Ecuador., Support Center for Advanced Neuroimaging, University Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern, Inselspital, University of Bern, Bern, Switzerland., Institute for Surgical Technology and Biomechanics, University of Bern, Bern, Switzerland., Institute of Neuroradiology, Neuromed Campus (NMC), Kepler University Hospital Linz, Linz, Austria., Department of Neurooncology, Neuromed Campus (NMC), Kepler University Hospital Linz, Linz, Austria., Institute of Diagnostic and Interventional Neuroradiology, RKH Klinikum Ludwigsburg, Ludwigsburg, Germany., Universidad de Concepción, Concepción, Chile., School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK., Department of Computer Engineering, Universidad Carlos III de Madrid, Madrid, Spain., Department of Industrial and Systems Engineering, University of Iowa, Iowa City, IA, USA., Department of Industrial and Systems Engineering, Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA., Department of NeuroRadiology, University of Patras, Patras, Greece., Department of Neurosurgery, University of Patras, Patras, Greece., Clinical Radiology Laboratory, Department of Medicine, University of Patras, Patras, Greece., Department of Electrical and Computer Engineering, University of Patras, Patras, Greece., Department of Radiation Oncology, University of Patras, Patras, Greece., Department of Radiation Oncology, Henry Ford Health, Detroit, MI, USA., Department of Public Health Sciences, Henry Ford Health, Detroit, MI, USA., Department of Computer Science, Université de Sherbrooke, Sherbrooke, QC, Canada., Centre de recherche du Centre hospitalier universitaire de Sherbrooke, Sherbrooke, QC, Canada., Division of Neurosurgery and Neuro-Oncology, Faculty of Medicine and Health Science, Université de Sherbrooke, Sherbrooke, QC, Canada., Department of Nuclear Medicine and Radiobiology, Sherbrooke Molecular Imaging Centre, Université de Sherbrooke, Sherbrooke, QC, Canada., Department of Radiology, Baylor College of Medicine, Houston, TX, USA., Department of Neurology, Baylor College of Medicine, Houston, TX, USA., Department of Radiation Oncology, Christiana Care Health System, Philadelphia, PA, USA., Department of Radiation Oncology, Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA., Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Department of Radiation Oncology, University of Maryland, Baltimore, MD, USA., Department of Radiation Oncology, James Cancer Center, The Ohio State University, Columbus, OH, USA., Department of Radiology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA., Department of Radiology, University College Hospital Ibadan, Oyo, Nigeria., Clinix Healthcare, Lagos, Lagos, Nigeria., Department of Radiology, Muhammad Abdullahi Wase Teaching Hospital, Kano, Nigeria., Department of Radiology, Obafemi Awolowo University Ile-Ife, Ile-Ife, Osun, Nigeria., Department of Neurosurgery, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Departments of Neurosurgery and Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Department of Radiology, Leeds Teaching Hospitals Trust, Leeds, UK., School of Computing, Queen's University, Kingston, ON, Canada., Department of Biomedical and Molecular Sciences, Queen&'s University, Kingston, ON, Canada., Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada., Faculty of Arts and Sciences, Queen's University, Kingston, ON, Canada., Department of Oncology, Queen 39;s University, Kingston, ON, Canada., Department of Electrical Engineering, Qazvin Branch, Islamic Azad University, Qazvin, Iran., Center for Research and Innovation, American College of Radiology, Philadelphia, PA, USA., American College of Radiology (ACR), Reston, VA, USA., Center for MR-Research, University Children's Hospital Zurich, Zurich, Switzerland., Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology, University Medical Center Rostock, Rostock, Germany., Department of Medical Imaging, Unity Health Toronto, University of Toronto, Toronto, ON, Canada., Institute for AI in Medicine (IKIM), University Hospital Essen, Essen, Germany., Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Pattern Analysis and Learning Group, Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany., Center for Federated Learning in Medicine, Indiana University, Indianapolis, IN, USA. spbakas@iu.edu., Division of Computational Pathology, Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. spbakas@iu.edu., Medical Research Group, MLCommons, San Francisco, CA, USA. spbakas@iu.edu., Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN, USA. spbakas@iu.edu., Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA. spbakas@iu.edu., Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. spbakas@iu.edu., Department of Computer Science, Luddy School of Informatics, Computing, and Engineering, Indiana University, Indianapolis, IN, USA. spbakas@iu.edu.,
    1. Year: 2025
    2. Date: Jul 08
    3. Epub Date: 2025 07 08
  2. Journal: Nature Communications
    1. 16
    2. 1
    3. Pages: 6274
  4. Type of Article: Article
  5. Article Number: 6274
  1. Abstract:

    Computational competitions are the standard for benchmarking medical image analysis algorithms, but they typically use small curated test datasets acquired at a few centers, leaving a gap to the reality of diverse multicentric patient data. To this end, the Federated Tumor Segmentation (FeTS) Challenge represents the paradigm for real-world algorithmic performance evaluation. The FeTS challenge is a competition to benchmark (i) federated learning aggregation algorithms and (ii) state-of-the-art segmentation algorithms, across multiple international sites. Weight aggregation and client selection techniques were compared using a multicentric brain tumor dataset in realistic federated learning simulations, yielding benefits for adaptive weight aggregation, and efficiency gains through client sampling. Quantitative performance evaluation of state-of-the-art segmentation algorithms on data distributed internationally across 32 institutions yielded good generalization on average, albeit the worst-case performance revealed data-specific modes of failure. Similar multi-site setups can help validate the real-world utility of healthcare AI algorithms in the future. © 2025. The Author(s).

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External Sources

  1. View Full Text
  2. DOI: 10.1038/s41467-025-60466-1
  3. PMID: 40628696
  4. PMCID: PMC12238412
  5. PII : 10.1038/s41467-025-60466-1

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  1. Fiscal Year: FY2024-2025
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