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HIV-Inhibitory prenylated xanthones and flavones from Maclura tinctoria

  1. Author:
    Groweiss, A.
    Cardellina, J. H.
    Boyd, M. R.

  2. Author Address

    Laboratory of Drug Discovery Research and Development, Developmental Therapeutic Program, Division of Cancer Treatment and Diagnosis, Frederick Cancer Research and Development Center, National Cancer Institute, Frederick, Maryland 21702-1201, USA.
    1. Year: 2000
  2. Journal: Journal of Natural Products
    1. 63
    2. 11
    3. Pages: 1537-1539
  4. Type of Article: Article
  1. Abstract:

    The organic extract of the plant Maclura tinctoria exhibited moderate anti-HIV activity. Seven prenylated phenolic derivatives were isolated from the active fractions and characterized by spectroanalytical methods. New compounds macluraxanthone B (1), macluraxanthone C (2), and dihydrocudraflavone B (8) were identified.

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