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Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor

  1. Author:
    Botos, I.
    Wu, Z. B.
    Lu, W. Y.
    Wlodawer, A.

  2. Author Address

    NCI, Prot Struct Sect, Macromol Crystallog Lab, Frederick, MD 21702 USA. NCI, Prot Struct Sect, Macromol Crystallog Lab, Frederick, MD 21702 USA. Univ Maryland, Inst Human Virol, Baltimore, MD 21201 USA. Wlodawer A NCI, Prot Struct Sect, Macromol Crystallog Lab, Frederick, MD 21702 USA.
    1. Year: 2001
  2. Journal: Febs Letters
    1. 509
    2. 1
    3. Pages: 90-94
  4. Type of Article: Article
  1. Abstract:

    The crystal structure of a cyclic form of a mutant of bovine pancreatic trypsin inhibitor has been solved at 1.0 Angstrom resolution. The protein was synthesized by native chemical ligation and its structure is almost indistinguishable from the previously described recombinant form of the same mutant; however, the new loop containing the former termini became much better ordered. (C) 2001 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.

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