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Biologically active proteins from natural product extracts

  1. Author:
    O'Keefe, B. R.

  2. Author Address

    NCI, Canc Res Ctr, Mol Targets Drug Discovery Program, Frederick, MD 21702 USA. NCI, Canc Res Ctr, Mol Targets Drug Discovery Program, Frederick, MD 21702 USA. O'Keefe BR NCI, Canc Res Ctr, Mol Targets Drug Discovery Program, Frederick, MD 21702 USA.
    1. Year: 2001
  2. Journal: Journal of Natural Products
    1. 64
    2. 10
    3. Pages: 1373-1381
  4. Type of Article: Review
  1. Abstract:

    The term "biologically active proteins" is almost redundant. All proteins produced by living creatures are, by their very nature, biologically active to some extent in their homologous species. In this review, a subset of these proteins will be discussed that are biologically active in heterologous systems. The isolation and characterization of novel proteins from natural product extracts including those derived from microorganisms, plants, insects, terrestrial vertebrates, and marine organisms will be reviewed and grouped into several distinct classes based on their biological activity and their structure.

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