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Power Frequency Magnetic Fields Do Not Contribute to Transformation of Jb6 Cells

  1. Author:
    Saffer, J. D.
    Chen, G.
    Colburn, N. H.
    Thurston, S. J.

  2. Author Address

    Saffer JD BATTELLE MEM INST PACIFIC NW LABS MOL BIOSCI DEPT POB 999 RICHLAND, WA 99352 USA BATTELLE MEM INST PACIFIC NW LABS ENGN & ANALYT SCI DEPT RICHLAND, WA 99352 USA NCI GENE REGULAT SECT LAB BIOCHEM PHYSIOL FREDERICK, MD 21702 USA
    1. Year: 1997
  2. Journal: Carcinogenesis
    1. 18
    2. 7
    3. Pages: 1365-1370
  4. Type of Article: Article
  1. Abstract:

    The potential for power frequency magnetic fields to enhance neoplastic transformation has been investigated in vitro using promotion-sensitive mouse epidermal JB6 cells, In a soft agar assay, 60-Hz magnetic fields of 0.01, 0.1, 1.0, or 1.1 mT flux density did not induce anchorage-independent growth, In addition, these magnetic fields did not enhance tumor promoter-induced transformation showing no increase in the maximum number of transformed colonies and no shift in the dose-response curve. Thus, these data do not support the notion that environmental exposures to magnetic fields contribute to transformation. [References: 23]

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