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Quantitative three-dimensional microscopy approaches with applications in breast cancer biology including measurement of genomic instability

  1. Author:
    Lockett, S.
    de Solorzano, C. O.
    Baggett, D.
    Chin, K.
  2. Author Address

    NCI, Frederick Sci Applicat Int Corp Frederick, Frederick, MD 21701 USA. Lawrence Berkeley Lab, Div Life Sci, Berkeley, CA USA. Worcester Polytech Inst, Worcester, MA 01609 USA. Univ Calif San Francisco, Dept Lab Med, San Francisco, CA 94143 USA. Univ Calif San Francisco, Ctr Comprehens Canc, San Francisco, CA 94143 USA Lockett, S, NCI, Frederick Sci Applicat Int Corp Frederick, Frederick, MD 21701 USA
    1. Year: 2004
    2. Date: OCT
  1. Journal: Journal of Mammary Gland Biology and Neoplasia
    1. 9
    2. 4
    3. Pages: 383-391
  2. Type of Article: Article
  1. Abstract:

    Understanding tissue development, tissue homeostasis and what goes wrong in these processes during tumorigenesis, requires knowledge of the kinetics of multiple, molecular pathways in individual cells while cells are in their tissue context. This review outlines progress and future directions necessary in quantitative microscopy for gaining this knowledge, using the mammary gland as a model system

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External Sources

  1. WOS: 000228525600007

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