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Mammalian phylogenomics comes of age

  1. Author:
    Murphy, W. J.
    Pevzner, P. A.
    O'Brien, S. J.

  2. Author Address

    NCI, Lab Genom Divers, SAIC Frederick, Basic Res Lab, Frederick, MD 21702 USA. Univ Calif San Diego, Dept Comp Sci & Engn, La Jolla, CA USA. NCI, Lab Genom Divers, Frederick, MD 21702 USA Murphy, WJ, Texas A&M Univ, Coll Vet Med & Biomed Sci, Dept Vet Integrat Biosci, College Stn, TX 77843 USA
    1. Year: 2004
    2. Date: DEC
  2. Journal: Trends in Genetics
    1. 20
    2. 12
    3. Pages: 631-639
  4. Type of Article: Review
  1. Abstract:

    The relatively new field of phylogenomics is beginning to reveal the potential of genomic data for evolutionary studies. As the cost of whole genome sequencing falls, anticipation of complete genome sequences from divergent species, reflecting the major lineages of modern mammals, is no longer a distant dream. In this article, we describe how comparative genomic data from mammals is progressing to resolve long-standing phylogenetic controversies, to refine dogma on how chromosomes evolve and to guide annotation of human and other vertebrate genomes

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  2. DOI: 10.1016/j.tig.2004.09.005
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