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PROSIT, an online service to calculate pseudorotational parameters of nucleosides and nucleotides

  1. Author:
    Sun, G. Y.
    Voigt, J. H.
    Marquez, V. E.
    Nicklaus, M. C.

  2. Author Address

    NCI, Med Chem Lab, CCR, NIH,DHHS, Frederick, MD 21702 USA Marquez, VE, NCI, Med Chem Lab, CCR, NIH,DHHS, 376 Boyles Dt, Frederick, MD 21702 USA
    1. Year: 2005
  2. Journal: Nucleosides Nucleotides & Nucleic Acids
    1. 24
    2. 5-7, Sp. Iss.
    3. Pages: 1029-1032
  4. Type of Article: Article
  1. Abstract:

    The online service PROSIT (Pseudo-Rotational Online Service and Interactive Tool) is a free service available at http://cactus.nci.nih.gov/prosit/ that performs pseudorotational analysis of nucleosides(tides). PROSIT reads the 3D coordinates of nucleosides and returns the pseudorotational phase angle P, puckering amplitude nu(max) and other related information. As examples the sugar conformations in a parallel-stranded guanine tetraplex and a four-way Holliday junction are presented here

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External Sources

  1. View record in Web of Science®
  2. WOS: 000232473500141

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