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Targeting the sticky fingers of HIV-1

  1. Author:
    Blumenthal, R.
    Dimitrov, D. S.

  2. Author Address

    NCI Frederick, Ctr Canc Res Nanobiol Program, NIH, Ft Detrick, MD 21702 USA.;Blumenthal, R, NCI Frederick, Ctr Canc Res Nanobiol Program, NIH, Ft Detrick, MD 21702 USA.;blumen@helix.nih.gov
    1. Year: 2007
    2. Date: Apr
  2. Journal: Cell
    1. 129
    2. 2
    3. Pages: 243-245
  4. Type of Article: Editorial Material
  5. ISSN: 0092-8674
  1. Abstract:

    Although human blood plasma contains molecules that inhibit the activity of HIV-1, their identity is largely unknown. Winch et al. (2007) now identify a peptide corresponding to a portion of alpha 1-antitrypsin that potently inhibits entry of HIV-1 into host cells by binding to a hydrophobic segment of the viral envelope glycoprotein gp41.

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External Sources

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  2. DOI: 10.1016/j.cell.2007.04.005
  3. View record in Web of Science®
  4. WOS: 000246474600011

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