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Human herpesvirus 8 seroprevalence among children and adolescents in the United States

  1. Author:
    Anderson, L. A.
    Li, Y.
    Graubard, B. I.
    Whitby, D.
    Mbisa, G.
    Tan, S.
    Goedert, J. J.
    Engels, E. A.

  2. Author Address

    Anderson, Lesley A.; Goedert, James J.; Engels, Eric A.] NCI, Div Canc Epidemiol & Genet, Infect & Immunoepidemiol Branch, Bethesda, MD 20892 USA. [Anderson, Lesley A.] NCI, NIH, Canc Prevent Fellowship Program, Off Prevent Oncol,Div Canc Prevent, Bethesda, MD 20892 USA. [Graubard, Barry I.] NCI, Div Canc Epidemiol & Genet, Biostat Branch, Bethesda, MD 20892 USA. [Whitby, Denise] NCI, SAIC Frederick, Viral Epidemiol Sect, AIDS Vaccine Program, Frederick, MD USA. [Tan, Sylvia] RTI Int, Rockville, MD USA.
    1. Year: 2008
  2. Journal: Pediatric Infectious Disease Journal
    1. 27
    2. 7
    3. Pages: 661-664
  4. Type of Article: Article
  1. Abstract:

    We measured human herpesvirus-8 antibodies (K8.1 and orf73 enzyme immunoassays) in 4166 children, aged 6-17 years, in a U.S. cross-sectional survey. Forty-six were K8.1 seropositive (weighted seroprevalence: 1.1%) and 20 were orf73 seropositive (weighted seroprevalence 0.4%). K8.1 seropositivity was associated with asthma (odds ratio: 6.3, 95% confidence interval: 2.4-16.9) and hay fever (3.5, 1.1-11.0), and there were borderline associations with measures of crowding and low socioeconomic status.

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External Sources

  1. PMID: 18536622

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