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Synthesis of a homologous series of side-chain-extended orthogonally protected aminooxy-containing amino acids

  1. Author:
    Liu, F.
    Thomas, J.
    Burke, T. R.

  2. Author Address

    Liu, Fa, Thomas, Joshua, Burke, Terrence R., Jr.] NCI, Med Chem Lab, CCR, NIH, Frederick, MD 21702 USA.
    1. Year: 2008
  2. Journal: Synthesis-Stuttgart
    1. 15
    2. Pages: 2432-2438
  4. Type of Article: Article
  1. Abstract:

    Practical methodology is reported for the synthesis of a homologous series of side-chain-extended amino acids containing aminooxy functionality bearing orthogonal protection suitable for Fmoc peptide synthesis. These reagents may be useful for the preparation of libraries containing fragments joined by peptide linkers.

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