Skip NavigationSkip to Content
Return Return to Search Results

Sequential Assignments and Secondary Structure of the Rna-Binding Transcriptional Regulator Nusb

  1. Author:
    Altieri, A. S.
    Mazzulla, M. J.
    Zhou, H. J.
    Costantino, N.
    Court, D. L.
    Byrd, R. A.

  2. Author Address

    Altieri AS NCI FREDERICK CANC RES & DEV CTR ABL BASIC RES PROGRAM MACROMOL NMR SECT POB B BLDG 538 FREDERICK, MD 21702 USA NCI FREDERICK CANC RES & DEV CTR ABL BASIC RES PROGRAM MOL CONTROL & GENET SECT FREDERICK, MD 21702 USA
    1. Year: 1997
  2. Journal: Febs Letters
    1. 415
    2. 2
    3. Pages: 221-226
  4. Type of Article: Article
  1. Abstract:

    The NusB protein is involved in transcriptional regulation in bacteriophage lambda. NusB binds to the RNA form of the nut site and along with N, NusA, NusE and NusG, stabilizes the RNA polymerase transcription complex and allows stable, persistent antitermination, NusB contains a 10 residue Arg-rich RNA-binding motif (ARM) at the N-terminus but is not sequentially homologous to any other proteins. In contrast to other known ARM-containing proteins, NusB forms a stable structure in solution in the absence of RNA, NMR spectroscopy was used to determine that NusB contains six alpha-helices: R10-Q21, I27-F34, V45-L65, Q79-S93, Y100-F114 and D118-L127. The structure of NusB makes it a member of a newly emerging class of alpha-helical RNA-binding proteins. (C) 1997 Federation of European Biochemical Societies. [References: 63]

    See More

  1. Keywords:

External Sources

  1. No sources found.

Library Notes

  1. No notes added.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel