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Vismiaphenones D-G, new prenylated benzophenones from Vismia cayennensis

  1. Author:
    Fuller, R. W.
    Westergaard, C. K.
    Collins, J. W.
    Cardellina, J. H.
    Boyd, M. R.

  2. Author Address

    Boyd MR NCI, Frederick Canc Res & Dev Ctr, Div Canc Treatment & Diag, Lab Drug Discovery Res & Dev,Dev Therapeut Progra Bldg 1052,Room 121 Frederick, MD 21702 USA NCI, Frederick Canc Res & Dev Ctr, Div Canc Treatment & Diag, Lab Drug Discovery Res & Dev,Dev Therapeut Progra Frederick, MD 21702 USA
    1. Year: 1999
  2. Journal: Journal of Natural Products
    1. 62
    2. 1
    3. Pages: 67-69
  4. Type of Article: Article
  1. Abstract:

    Following anti-HIV bioassay-guided fractionation, four new prenylated benzophenones, vismiaphenones D-G (7-10), were isolated from extracts of leaves of Vismia cayennensis. The structures were elucidated by spectral analyses. Only vismiaphenone D (7) exhibited HIV-inhibitory activity in the NCI primary screen. [References: 24]

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