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CD225 Proteins: A Family Portrait of Fusion Regulators

  1. Author:
    Coomer, Charles A.
    Rahman,Kazi
    Compton,Alex

  2. Author Address

    NCI, HIV Dynam & Replicat Program, Ctr Canc Res, Frederick, MD 21701 USA.
    1. Year: 2021
    2. Date: May
  2. Journal: Trends in Genetics
  3. Elsevier Sciences
    1. 37
    2. 5
    3. Pages: 406-410
  5. Type of Article: Article
  6. ISSN: 0168-9525
  1. Abstract:

    The CD225 superfamily regulates vesicular membrane fusion events essential to neurotransmission, immunity, development, and metabolism. Its importance to physiology is reinforced by the identification of polymorphisms associated with disease. This article highlights the shared features that drive the function of CD225 proteins such as interferon-inducible transmembrane proteins 3 (IFITM3) and proline-rich transmembrane protein 2 (PRRT2) and is intended to catalyze efforts towards characterizing the lesser-known family members.

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  1. Keywords:

External Sources

  1. View Full Text
  2. DOI: 10.1016/j.tig.2021.01.004
  3. PMID: 33518406
  4. View record in Web of Science®
  5. WOS: 000640179100003

Library Notes

  1. Fiscal Year: FY2020-2021
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