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Fun in the sun: ribosomes defend against UV irradiation

  1. Author:
    Coria,Aaztli
    Orgebin,Emilien
    Wu,Colin

  2. Author Address

    Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA., Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA. Electronic address: colin.wu2@nih.gov.,
    1. Year: 2025
    2. Date: Jan 16
    3. Epub Date: 2025 01 16
  2. Journal: Trends in Cell Biology
  4. Type of Article: Article
  1. Abstract:

    The concept that ribosomes are sensors of translational distress has sparked significant interest, although much of the research has been conducted in vitro. A new study by Vind et al. provides in vivo evidence that the ribotoxic stress response (RSR) serves as the first line of defense against ultraviolet (UV) radiation. Published by Elsevier Ltd.

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External Sources

  1. View Full Text
  2. DOI: 10.1016/j.tcb.2024.12.016
  3. PMID: 39824721
  4. PII : S0962-8924(24)00284-8

Library Notes

  1. Fiscal Year: FY2024-2025
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