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ProTherm and ProNIT: thermodynamic databases for proteins and protein-nucleic acid interactions

  1. Author:
    Kumar, M. D. S.
    Bava, K. A.
    Gromiha, M. M.
    Prabakaran, P.
    Kitajima, K.
    Uedaira, H.
    Sarai, A.

  2. Author Address

    Kyushu Inst Technol, Dept Biosci & Bioinformat, Iizuka, Fukuoka 8208502, Japan. Adv Technol Inst Inc, Shiki, Saitama 3530006, Japan. Natl Inst Adv Ind Sci & Technol AIST, CBRC, Koto Ku, Tokyo 1350064, Japan. NCI, Lab Expt & Computat Biol, NIH, Frederick, MD 21702 USA. Tsukuba Mat Informat Lab, Tsukuba, Ibaraki 3050051, Japan.;Sarai, A, Kyushu Inst Technol, Dept Biosci & Bioinformat, 680-4 Kawazu, Iizuka, Fukuoka 8208502, Japan.;sarai@bse.kyutech.ac.jp
    1. Year: 2006
    2. Date: Jan
  2. Journal: Nucleic Acids Research
    1. 34
    2. Pages: D204-D206
  4. Type of Article: Article
  5. ISSN: 0305-1048
  1. Abstract:

    ProTherm and ProNIT are two thermodynamic databases that contain experimentally determined thermodynamic parameters of protein stability and protein-nucleic acid interactions, respectively. The current versions of both the databases have considerably increased the total number of entries and enhanced search interface with added new fields, improved search, display and sorting options. As on September 2005, ProTherm release 5.0 contains 17 113 entries from 771 proteins, retrieved from 1497 scientific articles (similar to 20% increase in data from the previous version). ProNIT release 2.0 contains 4900 entries from 273 research articles, representing 158 proteins. Both databases can be queried using WWW interfaces. Both quick search and advanced search are provided on this web page to facilitate easy retrieval and display of the data from these databases. ProTherm is freely available online at http://gibk26.bse.kyutech.ac.jp/jouhou/Protherm/protherm. html and ProNIT at http://gibk26.bse. kyutech.ac.jp/jouhou/pronit/pronit.html.

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  2. DOI: 10.1093/nar/gkj103
  3. View record in Web of Science®
  4. WOS: 000239307700043

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