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  1. 1.   Quantification of irinotecan, SN38, and SN38G in human and porcine plasma by ultra high-performance liquid chromatography-tandem mass spectrometry and its application to hepatic chemoembolization
  2. Chen, X. H.; Peer, C. J.; Alfaro, R.; Tian, T.; Spencer, S. D.; Figg, W. D.
  3. Journal of Pharmaceutical and Biomedical Analysis. 2012, Mar; 62: 140-148.
  1. 2.   ASPS-1, A Novel Cell Line Manifesting Key Features of Alveolar Soft Part Sarcoma
  2. Kenney, S.; Vistica, D. T.; Stockwin, L. H.; Burkett, S.; Hollingshead, M. G.; Borgel, S. D.; Butcher, D. O.; Schrump, D. S.; Shoemaker, R. H.
  3. Journal of Pediatric Hematology Oncology. 2011, Jul; 33(5): 360-368.
  1. 3.   Proteomic Analysis of Nuclei Isolated from Cancer Cell Lines Treated with Indenoisoquinoline NSC 724998, a Novel Topoisomerase I Inhibitor
  2. Han, B. N.; Stockwin, L. H.; Hancock, C.; Yu, S. X.; Hollingshead, M. G.; Newton, D. L.
  3. Journal of Proteome Research. 2010, Aug 6; 9(8): 4016-4027.
  1. 4.   High Throughput Extraction of Plant, Marine and Fungal Specimens for Preservation of Biologically Active Molecules
  2. McCloud, T. G.
  3. Molecules. 2010, Jul; 15(7): 4526-4563.
  1. 5.   Exon Array Analyses across the NCI-60 Reveal Potential Regulation of TOP1 by Transcription Pausing at Guanosine Quartets in the First Intron
  2. Reinhold, W. C.; Mergny, J. L.; Liu, H. F.; Ryan, M.; Pfister, T. D.; Kinders, R.; Parchment, R.; Doroshow, J.; Weinstein, J. N.; Pommier, Y.
  3. Cancer Research. 2010, Mar; 70(6): 2191-2203.
  1. 6.   Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity
  2. Pfister, T. D.; Reinhold, W. C.; Agama, K.; Gupta, S.; Khin, S. A.; Kinders, R. J.; Parchment, R. E.; Tomaszewski, J. E.; Doroshow, J. H.; Pommier, Y.
  3. Molecular Cancer Therapeutics. 2009 8(7): 1878-1884.
  1. 7.   Therapeutic Vulnerability of an In Vivo Model of Alveolar Soft Part Sarcoma (ASPS) to Antiangiogenic Therapy
  2. Vistica, D. T.; Hollingshead, M.; Borgel, S. D.; Kenney, S.; Stockwin, L. H.; Raffeld, M.; Schrump, D. S.; Burkett, S.; Stone, G.; Butcher, D. O.; Shoemaker, R. H.
  3. Journal of Pediatric Hematology Oncology. 2009 31(8): 561-570.
  1. 8.   Arylstibonic acids: Novel inhibitors and activators of human topoisomerase IB
  2. Kim, H.; Cardellina, J. H.; Akee, R.; Champoux, J. J.; Stivers, J. T.
  3. Bioorganic Chemistry. 2008 36(4-6): 190-197.
  1. 9.   Identification of a new natural camptothecin analogue in targeted screening for HIF-1 alpha inhibitors
  2. Klausmeyer, P.; McCloud, T. G.; Melillo, G.; Scudiero, D. A.; Cardellina, J. H.; Shoemaker, R. H.
  3. Planta Medica. 2007, Jan; 73(1): 49-52.
  1. 10.   Synthesis and biological evaluation of bisindenoisoquinolines as topoisomerase I inhibitors
  2. Nagarajan, M.; Morrell, A.; Antony, S.; Kohlhagen, G.; Agama, K.; Pommier, Y.; Ragazzon, P. A.; Garbett, N. C.; Chaires, J. B.; Hollingshead, M.; Cushman, M.
  3. Journal of Medicinal Chemistry. 2006, Aug; 49(17): 5129-5140.
  1. 11.   Schedule-dependent inhibition of hypoxia-inducible factor-1 alpha protein accumulation, angiogenesis, and tumor growth by topotecan in U251-HRE glioblastoma xenografts
  2. Rapisarda, A.; Zalek, J.; Hollingshead, M.; Braunschweig, T.; Uranchimeg, B.; Bonomi, C. A.; Borgel, S. D.; Carter, J. P.; Hewitt, S. M.; Shoemaker, R. H.; Melillo, G.
  3. Cancer Research. 2004, OCT 1; 64(19): 6845-6848.
  1. 12.   A tale of two tumor targets: Topoisomerase I and tubulin. The Wall and Wani contribution to cancer chemotherapy
  2. Cragg, G. M.; Newman, D. J.
  3. Journal of Natural Products. 2004 67(2): 232-244.
  1. 13.   Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: Mechanism and therapeutic implications
  2. Rapisarda, A.; Uranchimeg, B.; Sordet, O.; Pommier, Y.; Shoemaker, R. H.; Melillo, G.
  3. Cancer Research. 2004 64(4): 1475-1482.
  1. 14.   Evaluation of the acid-cleavable isotope-coded affinity tag reagents: Application to camptothecin-treated cortical neurons
  2. Yu, L. R.; Conrads, T. P.; Uo, T.; Issaq, H. J.; Morrison, R. S.; Veenstra, T. D.
  3. Journal of Proteome Research. 2004, MAY-JUN; 3(3): 469-477.
  1. 15.   Identification of small molecule inhibitors of hypoxia- inducible factor 1 transcriptional activation pathway
  2. Rapisarda, A.; Uranchimeg, B.; Scudiero, D. A.; Selby, M.; Sausville, E. A.; Shoemaker, R. H.; Melillo, G.
  3. Cancer Research. 2002 62(15): 4316-4324.
  1. 16.   Proteome analysis of camptothecin-treated cortical neurons using isotope-coded affinity tags
  2. Yu, L. R.; Johnson, M. D.; Conrads, T. P.; Smith, R. D.; Morrison, R. S.; Veenstra, T. D.
  3. Electrophoresis. 2002 23(11): 1591-1598.
  1. 17.   Synthesis of new dihydroindeno 1,2-c isoquinoline and indenoisoquinolinium chloride topoisomerase I inhibitors having high in vivo anticancer activity in the hollow fiber animal model
  2. Jayaraman, M.; Fox, B. M.; Hollingshead, M.; Kohlhagen, G.; Pommier, Y.; Cushman, M.
  3. Journal of Medicinal Chemistry. 2002 45(1): 242-249.
  1. 18.   Testing of new agents in childhood cancer preclinical models: Meeting summary
  2. Houghton, P. J.; Adamson, P. C.; Blaney, S.; Fine, H. A.; Gorlick, R.; Haber, M.; Helman, L.; Hirschfeld, D.; Hollingshead, M. G.; Israel, M. A.; Lock, R. B.; Maris, J. M.; Merlino, G.; Patterson, W.; Reynolds, C. P.; Shannon, K.; Yu, A.; Yu, J.; Smith, M. A.
  3. Clinical Cancer Research. 2002 8(12): 3646-3657.
  1. 19.   Bisimidazoacridones induce a potent cytostatic effect in colon tumor cells that sensitizes them to killing by UCN-01
  2. Cholody, W. M.; Kosakowska-Cholody, T.; Michejda, C. J.
  3. Cancer Chemotherapy and Pharmacology. 2001 47(3): 241-249.
  1. 20.   Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein low-level expressing erythrocytes
  2. Abraham, E. H.; Shrivastav, B.; Salikhova, A. Y.; Sterling, K. M.; Johnston, N.; Guidotti, G.; Scala, S.; Litman, T.; Chan, K. C.; Arceci, R. J.; Steiglitz, K.; Herscher, L.; Okunieff, P.
  3. Blood Cells Molecules and Diseases. 2001, JAN-FEB; 27(1): 181-200.
  1. 21.   20-O-beta-glucopyranosyl camptothecin from Mostuea brunonis: A potential camptothecin pre-drug with improved solubility
  2. Dai, J. R.; Hallock, Y. F.; Cardellina, J. H.; Boyd, M. R.
  3. Journal of Natural Products. 1999 62(10): 1427-1429.
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