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  1. 1.   alpha-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands
  2. Ann, Jihyae; Czikora, Agnes; Saini, Amandeep S.; Zhou, Xiaoling; Mitchell, Gary A.; Lewin, Nancy E.; Peach, Megan; Blumberg, Peter M.; Lee, Jeewoo
  3. Journal of Medicinal Chemistry. 2018, Jul 26; 61(14): 6261-6276.
  1. 2.   N-Methyl-Substituted Fluorescent DAG-Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity
  2. Gal, N.; Kolusheva, S.; Kedei, N.; Telek, A.; Naeem, T. A.; Lewin, N. E.; Lim, L.; Mannan, P.; Garfield, S. H.; El Kazzouli, S.; Sigano, D. M.; Marquez, V. E.; Blumberg, P. M.; Jelinek, R.
  3. Chembiochem. 2011, Oct; 12(15): 2331-2340.
  1. 3.   Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities
  2. Raifman, O.; Kolusheva, S.; Comin, M. J.; Kedei, N.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E.; Jelinek, R.
  3. Febs Journal. 2010, Jan; 277(1): 233-243.
  1. 4.   Ceramides: Branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency
  2. Kang, J. H.; Garg, H.; Sigano, D. M.; Francella, N.; Blumenthal, R.; Marquez, V. E.
  3. Bioorganic & Medicinal Chemistry. 2009 17(4): 1498-1505.
  1. 5.   Differential binding modes of diacylglycerol (DAG) and DAG lactones to protein kinase C (PK-C)
  2. Sigano, D. M.; Peach, M. L.; Nacro, K.; Choi, Y.; Lewin, N. E.; Nicklaus, M. C.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2003 46(9): 1571-1579.
  1. 6.   Rational design of drugs that induce human immunodeficiency virus replication
  2. Hamer, D. H.; Bocklandt, S.; McHugh, L.; Chun, T. W.; Blumberg, P. M.; Sigano, D. M.; Marquez, V. E.
  3. Journal of Virology. 2003 77(19): 10227-10236.
  1. 7.   Synthetic diacylglycerols (DAG) and DAG-lactones as activators of protein kinase C (PK-C)
  2. Marquez, V. E.; Blumberg, P. M.
  3. Accounts of Chemical Research. 2003 36(6): 434-443.
  1. 8.   Diacylglycerol (DAG)-lactones, a new class of protein kinase C (PKC) agonists, induce apoptosis in LNCaP prostate cancer cells by selective activation of PKC alpha
  2. Garcia-Bermejo, M. L.; Leskow, F. C.; Fujii, T.; Wang, Q. M.; Blumberg, P. M.; Ohba, M.; Kuroki, T.; Han, K. C.; Lee, J.; Marquez, V. E.; Kazanietz, M. G.
  3. Journal of Biological Chemistry. 2002 277(1): 645-655.
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