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  1. 1.   Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase
  2. Ndongwe, T. P.; Adedeji, A. O.; Michailidis, E.; Ong, Y. T.; Hachiya, A.; March, B.; Ryan, E. M.; Rai, D. K.; Kirby, K. A.; Whatley, A. S.; Burke, D. H.; Johnson, M.; Ding, S. L.; Zheng, Y. M.; Liu, S. L.; Kodama, E. I.; Delviks-Frankenberry, K. A.; Pathak, V. K.; Mitsuya, H.; Parniak, M. A.; Singh, K.; Sarafianos, S. G.
  3. Nucleic Acids Research. 2012, Jan; 40(1): 345-359.
  1. 2.   HIV-1 Nucleocapsid Protein Increases Strand Transfer Recombination by Promoting Dimeric G-quartet Formation
  2. Shen, W.; Gorelick, R. J.; Bambara, R. A.
  3. Journal of Biological Chemistry. 2011, Aug; 286(34): 29838-29847.
  1. 3.   Blocking premature reverse transcription fails to rescue the HIV-1 nucleocapsid-mutant replication defect
  2. Thomas, J. A.; Shatzer, T. L.; Gorelick, R. J.
  3. Retrovirology. 2011, Jun; 8: 14.
  1. 4.   Initiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription
  2. Liu, S. X.; Harada, B. T.; Miller, J. T.; Le Grice, S. F. J.; Zhuang, X. W.
  3. Nature Structural & Molecular Biology. 2010, Dec; 17(12): 1453-U83.
  1. 5.   Nature, Position, and Frequency of Mutations Made in a Single Cycle of HIV-1 Replication
  2. Abram, M. E.; Ferris, A. L.; Shao, W.; Alvord, W. G.; Hughes, S. H.
  3. Journal of Virology. 2010, Oct; 84(19): 9864-9878.
  1. 6.   Reverse transcriptase in motion: Conformational dynamics of enzyme-substrate interactions
  2. Gotte, M.; Rausch, J. W.; March, B.; Sarafianos, S.; Le Grice, S. F. J.
  3. Biochimica Et Biophysica Acta-Proteins and Proteomics. 2010, May; 1804(5): 1202-1212.
  1. 7.   The Nucleoside Analogue D-carba T Blocks HIV-1 Reverse Transcription
  2. Boyer, P. L.; Vu, B. C.; Ambrose, Z.; Julias, J. G.; Warnecke, S.; Liao, C. Z.; Meier, C.; Marquez, V. E.; Hughes, S. H.
  3. Journal of Medicinal Chemistry. 2009 52(17): 5356-5364.
  1. 8.   Subtype-Specific Differences in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Connection Subdomain of CRF01_AE Are Associated with Higher Levels of Resistance to 3 '-Azido-3 '-Deoxythymidine
  2. Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Maldarelli, F.; Hase, S.; Takebe, Y.; Pathak, V. K.
  3. Journal of Virology. 2009 83(17): 8502-8513.
  1. 9.   Differential involvement of vascular endothelial growth factor in the survival of hypoxic colon cancer cells
  2. Calvani, M.; Trisciuoglio, D.; Bergamaschi, C.; Shoemaker, R. H.; Melillo, G.
  3. Cancer Research. 2008 68(1): 285-291.
  1. 11.   Mutations M184V and Y115F in HIV-1 Reverse Transcriptase Discriminate against "Nucleotide-competing Reverse Transcriptase Inhibitors"
  2. Ehteshami, M.; Scarth, B. J.; Tchesnokov, E. P.; Dash, C.; Le Grice, S.; Hallenberger, S.; Jochmans, D.; Gotte, M.
  3. Journal of Biological Chemistry. 2008 283(44): 29904-29911.
  1. 12.   Mutations in the U5 region adjacent to the primer binding site affect tRNA cleavage by human immunodeficiency virus type 1 reverse transcriptase in vivo
  2. Oh, J.; McWilliams, M. J.; Julias, J. G.; Hughes, S. H.
  3. Journal of Virology. 2008 82(2): 719-727.
  1. 13.   Mutations in human immunodeficiency virus type 1 nucleocapsid protein zinc fingers cause premature reverse transcription
  2. Thomas, J. A.; Bosche, W. J.; Shatzer, T. L.; Johnson, D. G.; Gorelick, R. J.
  3. Journal of Virology. 2008 82(19): 9318-9328.
  1. 14.   High-resolution NMR analysis of the conformations of native and base analog substituted retroviral and LTR-retrotransposon PPT primers
  2. Yi-Brunozzi, H. Y.; Brinson, R. G.; Brabazon, D. I.; Lener, D.; Le Grice, S.; Marino, J. P.
  3. Chemistry & Biology. 2008 15(3): 254-262.
  1. 15.   Inhibition of estradiol receptor/Src association and cell growth by an estradiol receptor alpha tyrosine-phosphorylated peptide
  2. Varricchio, L.; Migliaccio, A.; Castoria, G.; Yamaguchi, H.; de Falco, A.; Di Domenico, M.; Giovannelli, P.; Farrar, W.; Appella, E.; Auricchio, F.
  3. Molecular Cancer Research. 2007, Nov; 5(11): 1213-1221.
  1. 16.   HIV-1 protease dimer interface mutations that compensate for viral reverse transcriptase instability in infectious virions
  2. Olivares, I.; Mulky, A.; Boross, P. I.; Tozser, J.; Kappes, J. C.; Lopez-Galindez, C.; Menendez-Arias, L.
  3. Journal of Molecular Biology. 2007, Sep; 372(2): 369-381.
  1. 17.   Transgenic expression of human thymidylate synthase accelerates the development of hyperplasia and tumors in the endocrine pancreas
  2. Chen, M.; Rahman, L.; Voeller, D.; Kastanos, E.; Yang, S. X.; Feigenbaum, L.; Allegra, C.; Kaye, F. J.; Steeg, P.; Zajac-Kaye, M.
  3. Oncogene. 2007, Jul; 26(33): 4817-4824.
  1. 19.   Analysis of amino acids in the beta 7-beta 8 loop of human immunodeficiency virus type 1 reverse transcriptase for their role in virus replication
  2. Mulky, A.; Vu, B. C.; Conway, J. A.; Hughes, S. H.; Kappes, J. C.
  3. Journal of Molecular Biology. 2007, Feb; 365(5): 1368-1378.
  1. 20.   Mutations in the connection domain of HIV-1 reverse transcriptase increase 3 '-azido-3 '-deoxythymidine resistance
  2. Nikolenko, G. N.; Delviks-Frankenberry, K. A.; Palmer, S.; Maldarelli, F.; Fivash, M. J.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2007, Jan; 104(1): 317-322.
  1. 21.   Exploiting structurally diverse nucleoside analogs as probes of reverse transcription complexes
  2. Rausch, J. W.; Le Grice, S. F. J.
  3. Current HIV Research. 2007, Jan; 5(1): 11-22.
  1. 22.   Transmission electron microscopy reveals an optimal HIV-1 nucleocapsid aggregation with single-stranded nucleic acids and the mature HIV-1 nucleocapsid protein
  2. Mirambeau, G.; Lyonnais, S.; Coulaud, D.; Hameau, L.; Lafosse, S.; Jeusset, J.; Justome, A.; Delain, E.; Gorelick, R. J.; Le Cam, E.
  3. Journal of Molecular Biology. 2006, Dec; 364(3): 496-511.
  1. 23.   Effects of mutations in the human immunodeficiency virus type 1 gag gene on RNA packaging and recombination
  2. Nikolaitchik, O.; Rhodes, T. D.; Ott, D.; Hu, W. S.
  3. Journal of Virology. 2006, MAY; 80(10): 4691-4697.
  1. 24.   Combining mutations in HIV-1 reverse transcriptase with mutations in the HIV-1 polypurine tract affects RNase H cleavages involved in PPT utilization
  2. McWilliams, M. J.; Julias, J. G.; Sarafianos, S. G.; Alvord, W. G.; Arnold, E.; Hughes, S. H.
  3. Virology. 2006, May; 348(2): 378-388.
  1. 25.   Examining Ty3 polypurine tract structure and function by nucleoside analog interference
  2. Dash, C.; Marino, J. P.; Le Grice, S. F. J.
  3. Journal of Biological Chemistry. 2006, FEB 3; 281(5): 2773-2783.
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