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  1. 1.   ShiftScan: A tool for rapid analysis of high-throughput differential scanning fluorimetry data and compound prioritization
  2. Waterworth, Samantha C; Shenoy, Shilpa R; Sharma, Nirmala D; Wolcott,Chris; Donohue,Duncan; O'Keefe,Barry; Beutler,John
  3. Protein Science : a publication of the Protein Society. 2025, Mar; 34(3): e70055.
  1. 2.   HIF1a Plays a Crucial Role in the Development of TFE3-Rearranged Renal Cell Carcinoma by Orchestrating a Metabolic Shift Toward Fatty Acid Synthesis
  2. Nishizawa, Hidekazu; Funasaki, Shintaro; Ma, Wenjuan; Kubota, Yoshiaki; Watanabe, Kazuhide; Arima, Yuichiro; Kuroda, Shoichiro; Ito, Takaaki; Furuya, Mitsuko; Motoshima, Takanobu; Nishiyama, Akira; Mehanna, Sally; Satou, Yorifumi; Hasumi, Hisashi; Jikuya, Ryosuke; Makiyama, Kazuhide; Tamura, Tomohiko; Oike, Yuichi; Tanaka, Yasuhito; Suda, Toshio; Schmidt,Laura; Linehan, W Marston; Baba, Masaya; Kamba, Tomomi
  3. Genes to Cells : devoted to molecular & cellular mechanisms. 2025, Jan; 30(1): e13195.
  1. 3.   Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned
  2. Stransky, Laura A; Gao, Wenhua; Schmidt,Laura; Bi, Kevin; Ricketts, Christopher J; Ramesh, Vijyendra; James,Amy; Difilippantonio,Simone; Ileva,Lilia; Kalen,Joseph; Karim,Baktiar; Jeon, Albert; Morgan,Tamara; Warner,Andrew; Turan, Sevilay; Unite,Joanne; Tran,Bao; Choudhari,Sulbha; Zhao,Yongmei; Linn, Douglas E; Yun, Changhong; Dhandapani, Sripriya; Parab, Vaishali; Pinheiro, Elaine M; Morris,Nicole; He, Lixia; Vigeant, Sean M; Pignon, Jean-Christophe; Sticco-Ivins, Maura; Signoretti, Sabina; Van Allen, Eliezer M; Linehan, W Marston; Kaelin, William G
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Oct 08; 121(41): e2408549121.
  1. 4.   Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut
  2. Das, Arundhoti; Martinez-Ruiz, Gustavo Ulises; Bouladoux, Nicolas; Stacy, Apollo; Moraly, Josquin; Vega-Sendino, Maria; Zhao, Yongge; Lavaert, Marieke; Ding, Yi; Morales-Sanchez, Abigail; Harly, Christelle; Seedhom, Mina O; Chari,Raj; Awasthi, Parirokh; Ikeuchi, Tomoko; Wang, Yueqiang; Zhu, Jinfang; Moutsopoulos, Niki M; Chen, WanJun; Yewdell, Jonathan W; Shapiro, Virginia Smith; Ruiz, Sergio; Taylor, Naomi; Belkaid, Yasmine; Bhandoola, Avinash
  3. Immunity. 2024, May 14; 57(5): 1019-1036.
  1. 5.   Effects of Xylanase A double mutation on substrate specificity and structural dynamics
  2. MacDonald, Meagan E; Wells, Nicholas G M; Hassan,Bakar; Dudley, Joshua A; Walters,Kylie; Korzhnev, Dmitry M; Aramini, James M; Smith, Colin A
  3. Journal of Structural Biology. 2024, Mar 02; 108082.
  1. 6.   Conformational Dynamics Allows Sampling of an "Active-like" State by Oncogenic K-Ras-GDP
  2. Grudzien, Patrick; Jang,Hyunbum; Leschinsky, Nicholas; Nussinov,Ruth; Gaponenko, Vadim
  3. Journal of Molecular Biology. 2022, Jun 22; 167695.
  1. 7.   Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model
  2. Gebert, J; Gelincik, O; Oezcan-Wahlbrink, M; Marshall,Jason; Hernandez-Sanchez, A; Urban, K; Long, M; Cortes, E; Tosti, E; Katzenmaier, E M; Song,Yurong; Elsaadi, A; Deng, N; Vilar, E; Fuchs, V; Nelius, N; Yuan,; Ahadova, A; Sei, S; Shoemaker, R H; Umar, A; Wei, L; Liu, S; Bork, P; Edelmann, W; von Knebel Doeberitz, M; Lipkin, S M; Kloor, M
  3. Gastroenterology. 2021, Oct; 161(4): 1288-1302.e13.
  1. 9.   Hypoxia, partial EMT and collective migration: Emerging culprits in metastasis
  2. Saxena, Kritika; Jolly, Mohit Kumar; Kuppusamy,Balamurugan
  3. Translational oncology. 2020, NOV; 13(11):
  1. 10.   Vav1 is Essential for HIF-1a Activation via a Lysosomal VEGFR1-Mediated Degradation Mechanism in Endothelial Cells
  2. Hong,Jaewoo; Min,Yongfen; Wuest, Todd; Lin,Charles
  3. Cancers. 2020, JUN; 12(6): E1374.
  1. 11.   Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10
  2. Buel,Gwen; Chen,Xiang; Chari,Raj; O'Neill, Maura J; Ebelle, Danielle L; Jenkins, Conor; Sridharan, Vinidhra; Tarasov,Sergey; Tarasova,Nadya; Andresson,Thorkell; Walters,Kylie
  3. Nature communications. 2020, Mar 10; 11(1): 1291.
  1. 12.   The Rho/Rac Guanine Nucleotide Exchange Factor Vav1 Regulates Hif-1 alpha and Glut-1 Expression and Glucose Uptake in the Brain
  2. Hong,Jaewoo; Kim, Yurim; Yanpallewar,Sudhirkumar; Lin,Charles
  3. International journal of molecular sciences. 2020, FEB; 21(4):
  1. 13.   Conformational Switch to a beta-Turn in a Staphylococcal Quorum Sensing Signal Peptide Causes a Dramatic Increase in Potency
  2. Vasquez, Joseph K.; West, Korbin H. J.; Yang, Tian; Polaske, Thomas J.; Cornilescu,Gabriel; Tonelli, Marco; Blackwell, Helen E.
  3. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2020, JAN 15; 142(2): 750-761.
  1. 14.   Preclinical Evaluation of Discorhabdins in Antiangiogenic and Antitumor Models
  2. Harris, Emily M; Strope, Jonathan D; Beedie, Shaunna L; Huang, Phoebe A; Goey, Andrew K L; Cook, Kristina M; Schofield, Christopher J; Chau, Cindy H; Cadelis, Melissa M; Copp, Brent R; Gustafson, Kirk; Figg, William D
  3. Marine Drugs. 2018, Jul 19; 16(7): pii: E241.
  1. 15.   Anticancer activity of Schiff base-Poloxamer P85 combination against kidney cancer
  2. Dogan, Aysegul; Demirci, Selami; Telci, Dilek; Canikyan, Serli; Kongur, Merve; Dede, Bülent; Sahin, Fikrettin
  3. International urology and nephrology. 2018, Feb; 50(2): 247-255.
  1. 16.   Unequivocal determination of caulamidines A and B: application and validation of new tools in the structure elucidation tool box
  2. Milanowski, Dennis J.; Oku, Naoya; Cartner, Laura; Bokesch, Heidi; Williamson, R. Thomas; Sauri, Josep; Liu, Yizhou; Blinov, Kirill A.; Ding, Yuanqing; Li, Xing-Cong; Ferreira, Daneel; Walker, Larry A.; Khan, Shabana; Davies-Coleman, Michael T.; Kelley, Jim; McMahon, James B.; Martin, Gary E.; Gustafson, Kirk
  3. Chemical Science. 2018, Jan 14; 9(2): 307-314.
  1. 17.   Poloxamer P85 increases anticancer activity of Schiff base against prostate cancer in vitro and in vivo
  2. Demirci, Selami; Dogan, Aysegul; Turkmen, Nese Basak; Telci, Dilek; Caglayan, Ahmet B.; Beker, Mustafa C.; Kilic, Ertugrul; Ozkan, Ferda; Dede, Bulent; Sahin, Fikrettin
  3. ANTI-CANCER DRUGS. 2017, Sep; 28(8): 869-879.
  1. 18.   Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis
  2. Palmieri, Erika; Menga, Alessio; Martín-Pérez, Rosa; Quinto, Annamaria; Riera-Domingo, Carla; De Tullio, Giacoma; Hooper, Douglas C; Lamers, Wouter H; Ghesquière, Bart; McVicar, Daniel; Guarini, Attilio; Mazzone, Massimiliano; Castegna, Alessandra
  3. Cell Reports. 2017, Aug 15; 20(7): 1654-1666.
  1. 19.   A dynamic hydrophobic core orchestrates allostery in protein kinases
  2. Kim, Jonggul; Ahuja, Lalima G.; Chao, Frank; Xia, Youlin; McClendon, Christopher L.; Kornev, Alexandr P.; Taylor, Susan S.; Veglia, Gianluigi
  3. SCIENCE ADVANCES. 2017, APR; 3(4):
  1. 20.   Schiff base-Poloxamer P85 combination demonstrates chemotherapeutic effect on prostate cancer cells in vitro.
  2. Demirci, Selami; Dogan, Aysegül; Türkmen, Nese Basak; Telci, Dilek; Rizvanov, Albert A; Sahin, Fikrettin
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2017, Feb; 86: 492-501.
  1. 21.   Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production
  2. Baseler, Walter; Davies, Luke; Quigley, L.; Ridnour, Lisa; Weiss, Jonathan; Hussain, S. P.; Wink, David; McVicar, Daniel
  3. Redox biology. 2016, Dec; 10: 12-23.
  1. 22.   Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor
  2. Xu, X.; Hou, Y.; Yin, X. Y.; Bao, L.; Tang, A. F.; Song, L. T.; Li, F. Q.; Tsang, S.; Wu, K.; Wu, H. J.; He, W. M.; Zeng, L.; Xing, M. J.; Wu, R. H.; Jiang, H.; Liu, X.; Cao, D. D.; Guo, G. W.; Hu, X. D.; Gui, Y. T.; Li, Z. S.; Xie, W. Y.; Sun, X. J.; Shi, M.; Cai, Z. M.; Wang, B.; Zhong, M. M.; Li, J. X.; Lu, Z. H.; Gu, N.; Zhang, X. Q.; Goodman, L.; Bolund, L.; Wang, J.; Yang, H. M.; Kristiansen, K.; Dean, M.; Li, Y. R.
  3. Cell. 2012, Mar; 148(5): 886-895.
  1. 23.   C/EBP-delta regulates VEGF-C autocrine signaling in lymphangiogenesis and metastasis of lung cancer through HIF-1 alpha
  2. Min, Y.; Ghose, S.; Boelte, K.; Li, J.; Yang, L.; Lin, P. C.
  3. Oncogene. 2011, Dec; 30(49): 4901-4909.
  1. 24.   An NMR strategy for fragment-based ligand screening utilizing a paramagnetic lanthanide probe
  2. Saio, T.; Ogura, K.; Shimizu, K.; Yokochi, M.; Burke, T. R.; Inagaki, F.
  3. Journal of Biomolecular Nmr. 2011, Nov; 51(3): 395-408.
  1. 25.   Inactivation of the von Hippel-Lindau tumor suppressor leads to selective expression of a human endogenous retrovirus in kidney cancer
  2. Cherkasova, E.; Malinzak, E.; Rao, S.; Takahashi, Y.; Senchenko, V. N.; Kudryavtseva, A. V.; Nickerson, M. L.; Merino, M.; Hong, J. A.; Schrump, D. S.; Srinivasan, R.; Linehan, W. M.; Tian, X.; Lerman, M. I.; Childs, R. W.
  3. Oncogene. 2011, Nov; 30(47): 4697-4706.
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