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  1. 1.   Comparative Analyses of Antiviral Potencies of Second-Generation Integrase Strand Transfer Inhibitors (INSTIs) and the Developmental Compound 4d Against a Panel of Integrase Quadruple Mutants
  2. Smith,Steven; Zhao,Xuezhi; Hughes,Stephen; Burke,Terrence
  3. Viruses. 2025, Jan 16; 17(1):
  1. 2.   N-Substituted Bicyclic Carbamoyl Pyridones: Integrase Strand Transfer Inhibitors that Potently Inhibit Drug-Resistant HIV-1 Integrase Mutants
  2. Mahajan,Pankaj; Smith,Steven; Li, Min; Craigie, Robert; Hughes,Stephen; Zhao,Xuezhi; Burke,Terrence
  3. ACS Infectious Diseases. 2024, Feb 12;
  1. 3.   Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors
  2. Zhao, Xue Zhi; Smith, Steven; Maskell, Daniel P.; Metifiot, Mathieu; Pye, Valerie E.; Fesen, Katherine; Marchand, Christophe; Pommier, Yves; Cherepanov, Peter; Hughes, Stephen; Burke, Terrence
  3. Journal of Medicinal Chemistry. 2017, SEP 14; 60(17): 7315-7332.
  1. 4.   A Structural Basis for Reversible Photoswitching of Absorbance Spectra in Red Fluorescent Protein rsTagRFP
  2. Pletnev, S.; Subach, F. V.; Dauter, Z.; Wlodawer, A.; Verkhusha, V. V.
  3. Journal of Molecular Biology. 2012, Mar; 417(3): 144-151.
  1. 5.   MK-0536 Inhibits HIV-1 Integrases Resistant to Raltegravir
  2. Metifiot, M.; Johnson, B.; Smith, S.; Zhao, X. Z.; March, C.; Burke, T.; Hughes, S.; Pommier, Y.
  3. Antimicrobial Agents and Chemotherapy. 2011, Nov; 55(11): 5127-5133.
  1. 6.   A set of aspartyl protease-deficient strains for improved expression of heterologous proteins in Kluyveromyces lactis
  2. Ganatra, M. B.; Vainauskas, S.; Hong, J. M.; Taylor, T. E.; Denson, J. P. M.; Esposito, D.; Read, J. D.; Schmeisser, H.; Zoon, K. C.; Hartley, J. L.; Taron, C. H.
  3. Fems Yeast Research. 2011, Mar; 11(2): 168-178.
  1. 7.   Probing Cellular Processes with Oligo-Mediated Recombination and Using the Knowledge Gained to Optimize Recombineering
  2. Sawitzke, J. A.; Costantino, N.; Li, X. T.; Thomason, L. C.; Bubunenko, M.; Court, C.; Court, D. L.
  3. Journal of Molecular Biology. 2011, Mar; 407(1): 45-59.
  1. 8.   Mutations in the Thumb Allow Human Immunodeficiency Virus Type 1 Reverse Transcriptase To Be Cleaved by Protease in Virions
  2. Dunn, L. L.; McWilliams, M. J.; Das, K.; Arnold, E.; Hughes, S. H.
  3. Journal of Virology. 2009 83(23): 12336-12344.
  1. 9.   Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals
  2. Montcouquiol, M.; Sans, N.; Huss, D.; Kach, J.; Dickman, J. D.; Forge, A.; Rachel, R. A.; Copeland, N. G.; Jenkins, N. A.; Bogani, D.; Murdoch, J.; Warchol, M. E.; Wenthold, R. J.; Kelley, M. W.
  3. Journal of Neuroscience. 2006, MAY 10; 26(19): 5265-5275.
  1. 10.   Effects of mutations in the human immunodeficiency virus type 1 gag gene on RNA packaging and recombination
  2. Nikolaitchik, O.; Rhodes, T. D.; Ott, D.; Hu, W. S.
  3. Journal of Virology. 2006, MAY; 80(10): 4691-4697.
  1. 11.   Effects of Gag mutation and processing on retroviral dimeric RNA maturation
  2. Fu, W.; Dang, Q.; Nagashima, K.; Freed, E. O.; Pathak, V. K.; Hu, W. S.
  3. Journal of Virology. 2006, FEB; 80(3): 1242-1249.
  1. 12.   Mutations in the U5 sequences adjacent to the primer binding site do not affect tRNA cleavage by Rous sarcoma virus RNase H but do cause aberrant integrations in vivo
  2. Oh, J.; Chang, K. W.; Hughes, S. H.
  3. Journal of Virology. 2006, JAN; 80(1): 451-459.
  1. 13.   ProTherm and ProNIT: thermodynamic databases for proteins and protein-nucleic acid interactions
  2. Kumar, M. D. S.; Bava, K. A.; Gromiha, M. M.; Prabakaran, P.; Kitajima, K.; Uedaira, H.; Sarai, A.
  3. Nucleic Acids Research. 2006, Jan; 34: D204-D206.
  1. 14.   Potent neutralization of Hendra and Nipah viruses by human monoclonal antibodies
  2. Zhu, Z. Y.; Dimitrov, A. S.; Bossart, K. N.; Crameri, G.; Bishop, K. A.; Choudhry, V.; Mungall, B. A.; Feng, Y. R.; Choudhary, A.; Zhang, M. Y.; Feng, Y.; Wang, L. F.; Xiao, X. D.; Eaton, B. T.; Broder, C. C.; Dimitrov, D. S.
  3. Journal of Virology. 2006, JAN; 80(2): 891-899.
  1. 15.   Multifunctional roles of the conserved arg residues in the second region of homology of p97/valosin-containing protein
  2. Wang, Q.; Song, C. C.; Irizarry, L.; Dai, R. M.; Zhang, X. D.; Li, C. C. H.
  3. Journal of Biological Chemistry. 2005, DEC 9; 280(49): 40515-40523.
  1. 16.   Crystal structures for HIV-1 reverse transcriptase in complexes with three pyridinone derivatives: A new class of non-nucleoside inhibitors effective against a broad range of drug-resistant strains
  2. Himmel, D. M.; Das, K.; Clark, A. D.; Hughes, S. H.; Benjahad, A.; Oumouch, S.; Guillemont, J.; Coupa, S.; Poncelet, A.; Csoka, I.; Meyer, C.; Andries, K.; Nguyen, C. H.; Grierson, D. S.; Arnold, E.
  3. Journal of Medicinal Chemistry. 2005, DEC 1; 48(24): 7582-7591.
  1. 17.   Suppression of p65 phosphorylation coincides with inhibition of I kappa B alpha polyubiquitination and degradation
  2. Hu, J.; Haseebuddin, M.; Young, M.; Colburn, N. H.
  3. Molecular Carcinogenesis. 2005, DEC; 44(4): 274-284.
  1. 18.   The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe
  2. Thon, G.; Hansen, K. R.; Altes, S. P.; Sidhu, D.; Singh, G.; Verhein-Hansen, J.; Bonaduce, M. J.; Klart, A. J. S.
  3. Genetics. 2005, DEC; 171(4): 1583-1595.
  1. 19.   Association of human immunodeficiency virus type 1 gag with membrane does not require highly basic sequences in the nucleocapsid: Use of a novel gag multimerization assay
  2. Ono, A.; Waheed, A. A.; Joshi, A.; Freed, E. O.
  3. Journal of Virology. 2005, NOV; 79(22): 14131-14140.
  1. 20.   Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning
  2. Verheyden, J. M.; Lewandoski, M.; Deng, C. X.; Harfe, B. D.; Sun, X.
  3. Development. 2005, OCT; 132(19): 4235-4245.
  1. 21.   Multiple roles of Rbx1 in the VBC-Cul2 ubiquitin ligase complex
  2. Megumi, Y.; Miyauchi, Y.; Sakurai, H.; Nobeyama, H.; Lorick, K.; Nakamura, E.; Chiba, T.; Tanaka, K.; Weissman, A. M.; Kirisako, T.; Ogawa, O.; Iwai, K.
  3. Genes to Cells. 2005, JUL; 10(7): 679-691.
  1. 22.   Phosphorylation of Ser(24) in the pleckstrin homology domain of insulin receptor substrate-1 by mouse Pelle-like kinase/interleukin-1 receptor-associated kinase - Cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance
  2. Kim, J. A.; Yeh, D. C.; Ver, M.; Li, Y. H.; Carranza, A.; Conrads, T. P.; Veenstra, T. D.; Harrington, M. A.; Quon, M. J.
  3. Journal of Biological Chemistry. 2005, JUN 17; 280(24): 23173-23183.
  1. 23.   Structural determinants of HIV-1 nucleocapsid protein for cTAR DNA binding and destabilization, and correlation with inhibition of self-primed DNA synthesis
  2. Beltz, H.; Clauss, C.; Piemont, E.; Ficheux, D.; Gorelick, R. J.; Roques, B.; Gabus, C.; Darlix, J. L.; de Rocquigny, H.; Mely, Y.
  3. Journal of Molecular Biology. 2005, MAY 20; 348(5): 1113-1126.
  1. 24.   Specific interactions between HIV-1 nucleocapsid protein and the TAR element
  2. Kanevsky, I.; Chaminade, F.; Ficheux, D.; Moumen, A.; Gorelick, R.; Negroni, M.; Darlix, J. L.; Fosse, P.
  3. Journal of Molecular Biology. 2005, MAY 20; 348(5): 1059-1077.
  1. 25.   Structural basis for the function of stringent starvation protein A as a transcription factor
  2. Hansen, A. M.; Gu, Y. J.; Li, M.; Andrykovitch, M.; Waugh, D. S.; Jin, D. J.; Ji, X. H.
  3. Journal of Biological Chemistry. 2005, APR 29; 280(17): 17380-17391.
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