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  1. 1.   Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
  2. Magnussen, Helge M.; Ahmed, Syed F.; Sibbet, Gary J.; Hristova, Ventzislava A.; Nomura, Koji; Hock, Andreas K.; Archibald, Lewis J.; Jamieson, Andrew G.; Fushman, David; Vousden, Karen H.; Weissman, Allan M.; Huang, Danny T.
  3. Nature communications. 2020, Apr 29; 11(1):
  1. 2.   Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53
  2. Clement, J. A.; Kitagaki, J.; Yang, Y.; Saucedo, C. J.; O'Keefe, B. R.; Weissman, A. M.; Mckee, T. C.; McMahon, J. B.
  3. Bioorganic & Medicinal Chemistry. 2008 16(23): 10022-10028.
  1. 3.   HDM2 phosphorylation by MAPKAP kinase 2
  2. Weber, H. O.; Ludwig, R. L.; Morrison, D.; Kotlyarov, A.; Gaestel, M.; Vousden, K. H.
  3. Oncogene. 2005, MAR 17; 24(12): 1965-1972.
  1. 4.   Assay for ubiquitin ligase activity: High-throughput screen for inhibitors of HDM2
  2. Davydov, I. V.; Woods, D.; Safiran, Y. J.; Oberoi, P.; Fearnhead, H. O.; Fang, S.; Jensen, J. P.; Weissman, A. M.; Kenten, J. H.; Vousden, K. H.
  3. Journal of Biomolecular Screening. 2004, DEC; 9(8): 695-703.
  1. 5.   C-terminal ubiquitination of p53 contributes to nuclear export
  2. Lohrum, M. A. E.; Woods, D. B.; Ludwig, R. L.; Balint, E.; Vousden, K. H.
  3. Molecular and Cellular Biology. 2001 21(24): 8521-8532.
  1. 6.   Analysis of the degradation function of Mdm2
  2. Kubbutat, M. H. G.; Ludwig, R. L.; Levine, A. J.; Vousden, K. H.
  3. Cell Growth and Differentiation. 1999 10(2): 87-92.
  1. 7.   Regulation of p53 stability
  2. Ashcroft, M.; Vousden, K. H.
  3. Oncogene. 1999 18(53): 7637-7643.
  1. 8.   Regulation of P53 Stability By Mdm2
  2. Kubbutat, M. H. G.; Jones, S. N.; Vousden, K. H.
  3. Nature. 1997 387(6630): 299-303.
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