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  1. 1.   Olaparib in treatment-refractory isocitrate dehydrogenase 1 (IDH1)- and IDH2-mutant cholangiocarcinoma: Safety and antitumor activity from the phase 2 National Cancer Institute 10129 trial
  2. Cecchini, Michael; Pilat, Mary Jo; Uboha, Nataliya; Azad, Nilofer S; Cho, May; Davis, Elizabeth J; Ahnert, Jordi Rodon; Tinoco, Gabriel; Shapiro, Geoffrey I; Khagi, Simon; Powers, Benjamin; Spencer, Kristen; Groisberg, Roman; Drappatz, Jan; Chen, Li; Das,Bishu; Bao, Xun; Li, Jing; Narayan, Azeet; Vu, Dennis; Patel, Abhijit; Niger, Monica; Doroshow, Deborah; Durecki, Diane; Boerner, Scott A; Bindra, Ranjit; Ivy, Percy; Shyr, Derek; Shyr, Yu; LoRusso, Patricia M
  3. Cancer. 2025, Feb 15; 131(4): e35755.
  1. 2.   Purification of Circular RNAs Using Poly(A) Tailing Followed by RNase R Digestion
  2. Xiao, Mei-Sheng; Wilusz, Jeremy E
  3. Methods in Molecular Biology (Clifton, N.J.). 2024 2765: 3-19.
  1. 3.   Robust regulation of transcription pausing in Escherichia coli by the ubiquitous elongation factor NusG
  2. Yakhnin,Alex; Bubunenko,Mikhail; Mandell, Zachary F; Lubkowska,Lucyna; Husher, Sara; Babitzke, Paul; Kashlev,Mikhail
  3. Proceedings of the National Academy of Sciences of the United States of America. 2023, Jun 13; 120(24): e2221114120.
  1. 4.   Structure of Helicobacter pylori dihydroneopterin aldolase suggests a fragment-based strategy for isozyme-specific inhibitor design
  2. Shaw,Gary; Fan,Lixin; Cherry,Scott; Shi,Genbin; Tropea, Joseph E; Ji,Xinhua
  3. Current Research in Structural Biology. 2023, Jan 30; 5: 100095.
  1. 5.   Homologs of the Escherichia coli F Element Protein TraR, Including Phage Lambda Orf73, Directly Reprogram Host Transcription
  2. Gopalkrishnan, Saumya; Ross, Wilma; Akbari, Madeline S; Li, Xintian; Haycocks, James R J; Grainger, David C; Court,Don; Gourse, Richard L
  3. mBio. 2022, May 18; e0095222.
  1. 6.   Transcriptome-Wide Effects of NusA on RNA Polymerase Pausing in Bacillus subtilis
  2. Jayasinghe, Oshadhi T; Mandell, Zachary F; Yakhnin,Alex; Kashlev,Mikhail; Babitzke, Paul
  3. Journal of Bacteriology. 2022, Mar 08; e0053421.
  1. 7.   MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome"
  2. Das, Subhendu K.; Kuzin, Vladislav; Cameron, Donald P.; Sanford, Suzanne; Jha, Rajiv Kumar; Nie, Zuqin; Rosello, Marta Trullols; Holewinski,Ronald; Andresson,Thorkell; Wisniewski, Jan; Natsume, Toyoaki; Price, David H.; Lewis, Brian A.; Kouzine, Fedor; Levens, David; Baranello, Laura
  3. Molecular Cell. 2022, Jan 6; 82(1): 140-158. e12.
  1. 8.   Iterative epigenomic analyses in the same single cell
  2. Ohnuki, Hidetaka; Venzon, David J.; Lobanov,Alexei; Tosato, Giovanna
  3. Genome Research. 2021, Oct; 31(11): 1819-1830.
  1. 9.   SARS-CoV-2: from its discovery to genome structure, transcription, and replication
  2. Castro Brant,Ayslan; Tian, Wei; Majerciak,Vladimir; Yang, Wei; Zheng,Zhi-Ming
  3. Cell & bioscience. 2021, Jul 19; 11(1):
  1. 10.   The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences
  2. Newman, Jane D.; Russell, Meghan M.; Fan,Lixin; Wang,Yun-Xing; Gonzalez-Gutierrez, Giovanni; van Kessel, Julia C.
  3. Nucleic acids research. 2021, Jun 4; 49(10): 5967-5984.
  1. 11.   Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines
  2. Nance,Kellie; Meier,Jordan
  3. ACS central science. 2021, May 26; 7(5): 748-756.
  1. 12.   Safety, Antitumor Activity, and Biomarker Analysis in a Phase I Trial of the Once-daily Wee1 Inhibitor Adavosertib (AZD1775) in Patients with Advanced Solid Tumors
  2. Takebe, Naoko; Naqash, Abdul Rafeh; Coyne, Geraldine O'Sullivan; Kummar, Shivaani; Do, Khanh; Bruns, Ashley; Juwara,Lamin; Zlott, Jennifer; Rubinstein, Larry; Piekarz, Richard; Sharon, Elad; Streicher, Howard; Mittra, Arjun; Miller, Sarah B.; Ji,Jay; Wilsker,Deborah; Kinders,Robert; Parchment,Ralph; Chen,Li; Chang,Ting-Chia; Das,Biswajit; Mugundu, Ganesh; Doroshow, James H.; Chen, Alice P.
  3. CLINICAL CANCER RESEARCH. 2021, Apr 16; 27(14): 3834-3844.
  1. 13.   NusG-dependent RNA polymerase pausing is a frequent function of this universally conserved transcription elongation factor
  2. Yakhnin, Alexander V; Kashlev,Mikhail; Babitzke, Paul
  3. Critical reviews in biochemistry and molecular biology. 2020, Oct 02; 1-13.
  1. 14.   NusG controls transcription pausing and RNA polymerase translocation throughout the Bacillus subtilis genome
  2. Yakhnin, Alexander V; FitzGerald, Peter C; McIntosh, Carl; Yakhnin, Helen; Kireeva, Maria; Turek-Herman, Joshua; Mandell, Zachary F; Kashlev,Mikhail; Babitzke, Paul
  3. Proceedings of the National Academy of Sciences of the United States of America. 2020, SEP 1; 117(35): 21628-21636.
  1. 15.   Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability
  2. Kharat,Suhas; Ding, Xia; Swaminathan, Divya; Suresh, Akshey; Singh, Manish; Sengodan,Satheesh; Burkett,Sandra; Marks, Hanna; Pamala, Chinmayi; He,Yafeng; Fox,Stephen; Buehler, Eugen C; Muegge,Kathrin; Martin, Scott E; Sharan,Shyam
  3. Science signaling. 2020, Aug 18; 13(645): pii: eaba8091.
  1. 16.   Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age
  2. Ferreira, Rita; Schneekloth,Jay; Panov, Konstantin I.; Hannan, Katherine M.; Hannan, Ross D.
  3. Cells. 2020, FEB; 9(2):
  1. 17.   Sensitivity of mesothelioma cells to PARP inhibitors is not dependent on BAP1 but is enhanced by temozolomide in cells with high-Schlafen 11and low-MGMT expression
  2. Rathkey, Daniel; Khanal, Manakamana; Murai, Junko; Zhang, Jingli; Sengupta, Manjistha; Jiang, Qun; Morrow, Betsy; Evans,Christine; Chari,Raj; Fetsch, Patricia; Chung, Hye-Jung; Xi, Liqiang; Roth, Mark; Filie, Armando; Raffeld, Mark; Thomas, Anish; Pommier, Yves; Hassan, Raffit
  3. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2020, Jan 28; pii: S1556-0864(20)30035-6.
  1. 18.   NusG-Dependent RNA Polymerase Pausing and Tylosin-Dependent Ribosome Stalling Are Required for Tylosin Resistance by Inducing 23S rRNA Methylation in Bacillus subtilis
  2. Yakhnin, Helen; Yakhnin, Alexander V; Mouery, Brandon L; Mandell, Zachary F; Karbasiafshar, Catherine; Kashlev,Mikhail; Babitzke, Paul
  3. mBio. 2019, Nov; 10(6): pii: e02665-19..
  1. 19.   Spatial organization of RNA polymerase and its relationship with transcription in Escherichia coli
  2. Weng, Xiaoli; Bohrer, Christopher H; Bettridge, Kelsey; Lagda, Arvin Cesar; Cagliero, Cedric; Jin, Ding Jun; Xiao, Jie
  3. Proceedings of the National Academy of Sciences of the United States of America. 2019, OCT 1; 116(40): 20115-20123.
  1. 20.   The Role of Pyrophosphorolysis in the Initiation-to-Elongation Transition by E. coli RNA Polymerase
  2. Imashimizu, Masahiko; Kireeva, Maria L; Lubkowska,Lucyna; Kashlev,Mikhail; Shimamoto, Nobuo
  3. Journal of molecular biology. 2019, Jun 28; 431(14): 2528-2542.
  1. 21.   Structures and operating principles of the replisome
  2. Gao, Yang; Cui, Yanxiang; Fox,Tara; Lin, Shiqiang; Wang, Huaibin; De Val Alda,Natalia; Zhou, Z. Hong; Yang, Wei
  3. Science (New York, N.Y.). 2019, Feb 22; 363: 835-+.
  1. 22.   Extrachromosomal Nucleolus-Like Compartmentalization by a Plasmid-Borne Ribosomal RNA Operon and Its Role in Nucleoid Compaction
  2. Mata Martin, Carmen; Sun, Zhe; Zhou, Yan; Jin, Ding
  3. Frontiers in Microbiology. 2018, Jun 5; 9: 1115.
  1. 23.   Structural basis of transcriptional stalling and bypass of abasic DNA lesion by RNA polymerase II
  2. Wang, Wei; Walmacq, Celine; Chong, Jenny; Kashlev, Mikhail; Wang, Dong
  3. Proceedings of the National Academy of Sciences of the United States of America. 2018, Mar 13; 115(11): E2538-E2545.
  1. 24.   Cholecystokinin Receptor-Targeted Polyplex Nanoparticle Inhibits Growth and Metastasis of Pancreatic Cancer
  2. Burks, Julian; Nadella, Sandeep; Mahmud, Abdullah; Mankongpaisarnrung, Charoen; Wang, Juan; Hahm, Jong-In; Tucker, Robin D; Shivapurkar, Narayan; Stern, Steve; Smith, Jill P
  3. Cellular and Molecular Gastroenterology and Hepatology. 2018, Mar 07; 6(1): 17-32.
  1. 25.   Tail tubular protein A: a dual-function tail protein of Klebsiella pneumoniae bacteriophage KP32
  2. Pyra, Anna; Brzozowska, Ewa; Pawlik, Krzysztof; Gamian, Andrzej; Dauter, Miroslawa; Dauter, Zbigniew
  3. SCIENTIFIC REPORTS. 2017, May 22; 7
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