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  1. 1.   Targeting the extrinsic apoptosis signaling pathway for cancer therapy
  2. Sayers, T. J.
  3. Cancer Immunology Immunotherapy. 2011, Aug; 60(8): 1173-1180.
  1. 2.   Drozitumab, a Human Antibody to Death Receptor 5, Has Potent Antitumor Activity against Rhabdomyosarcoma with the Expression of Caspase-8 Predictive of Response
  2. Kang, Z. G.; Chen, J. J.; Yu, Y. K.; Li, B.; Sun, S. Y.; Zhang, B. L.; Cao, L.
  3. Clinical Cancer Research. 2011, May; 17(10): 3181-3192.
  1. 3.   Breast cancer bone metastases Combination therapy targeting cancer cells and the tumor microenvironment
  2. de Kluyver, R. L.; Sayers, T. J.
  3. Cancer Biology & Therapy. 2010, Apr; 9(7): 551-553.
  1. 4.   Identification and characterization of a novel agonistic anti-DR4 human monoclonal antibody
  2. Feng, Y.; Xiao, X. D.; Zhu, Z. Y.; Dimitrov, D. S.
  3. Mabs. 2010, Sep-Oct; 2(5): 565-570.
  1. 5.   Sensitizing tumor cells to immune-mediated cytotoxicity
  2. Shanker, A.; Sayers, T.
  3. Immune-Mediated Diseases: From Theory to Therapy. 2007; 601 : 163-171.
  1. 6.   Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy
  2. Sayers, T. J.; Murphy, W. J.
  3. Cancer Immunology Immunotherapy. 2006, JAN; 55(1): 76-84.
  1. 7.   Reduction of the antiapoptotic protein cFLIP enhances the susceptibility of human renal cancer cells to TRAIL apoptosis
  2. Brooks, A. D.; Sayers, T. J.
  3. Cancer Immunology Immunotherapy. 2005, MAY; 54(5): 499-505.
  1. 8.   The proteasome inhibitor bortezomib (Velcade) sensitizes some human tumor cells to Apo2L/TRAIL-mediated apoptosis
  2. Brooks, A. D.; Ramirez, T.; Toh, U.; Onksen, J.; Elliott, P. J.; Murphy, W. J.; Sayers, T. J.
  3. Tumor Progression and Therapeutic Resistance. 2005; 1059 : 160-167.
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