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  1. 1.   PAM3 protects against DSS-induced colitis by altering the M2:M1 ratio
  2. Horuluoglu, Begum H; Kayraklioglu, Neslihan; Tross,Debra; Klinman,Dennis
  3. Scientific reports. 2020, Apr 08; 10(1): 6078.
  1. 2.   Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23
  2. Chen, Lili; Strohmeier, Valentina; He, Zhengxiang; Deshpande, Madhura; Catalan-Dibene, Jovani; Durum,Scott; Moran, Thomas M; Kraus, Thomas; Xiong, Huabao; Faith, Jeremiah J; Sodhi, Chhinder P; Hackam, David J; Lira, Sergio A; Furtado, Glaucia C
  3. Nature communications. 2019, Oct 04; 10(1): 4517.
  1. 3.   Inherited p40(phox) deficiency differs from classic chronic granulomatous disease
  2. van de Geer, Annemarie; Nieto-Patlan, Alejandro; Kuhns, Doug; Tool, Anton T. J.; Arias, Andres A.; Bouaziz, Matthieu; de Boer, Martin; Luis Franco, Jose; Gazendam, Roel P.; van Hamme, John L.; van Houdt, Michel; van Leeuwen, Karin; Verkuijlen, Paul J. H.; van den Berg, Timo K.; Alzate, Juan F.; Arango-Franco, Carlos A.; Batura, Vritika; Bernasconi, Andrea R.; Boardman, Barbara; Booth, Claire; Burns, Siobhan O.; Cabarcas, Felipe; Bensussan, Nadine Cerf; Charbit-Henrion, Fabienne; Corveleyn, Anniek; Deswarte, Caroline; Esnaola Azcoiti, Maria; Foell, Dirk; Gallin, John I.; Garces, Carlos; Guedes, Margarida; Hinze, Claas H.; Holland, Steven M.; Hughes, Stephen M.; Ibanez, Patricio; Malech, Harry L.; Meyts, Isabelle; Moncada-Velez, Marcela; Moriya, Kunihiko; Neves, Esmeralda; Oleastro, Matias; Perez, Laura; Rattina, Vimel; Oleaga-Quintas, Carmen; Warner, Neil; Muise, Aleixo M.; Serafin Lopez, Jeanet; Trindade, Eunice; Vasconcelos, Julia; Vermeire, Severine; Wittkowski, Helmut; Worth, Austen; Abel, Laurent; Dinauer, Mary C.; Arkwright, Peter D.; Roos, Dirk; Casanova, Jean-Laurent; Kuijpers, Taco W.; Bustamante, Jacinta
  3. Journal of Clinical Investigation. 2018, Aug 31; 128(9): 3957-3975.
  1. 4.   Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease
  2. Mao, Liming; Kitani, Atsushi; Similuk, Morgan; Oler, Andrew J.; Albenberg, Lindsey; Kelsen, Judith; Aktay, Atiye; Quezado, Martha; Yao, Michael; Montgomery-Recht, Kim; Fuss, Ivan J.; Strober, Warren
  3. Journal of Clinical Investigation. 2018, May 01; 128(5): 1793-1806.
  1. 5.   Circulating Endothelial Progenitor Cells in Crohn's Disease: An EPiC in the Making?
  2. Dietrich, Catharine; Singh, Shree Ram
  3. DIGESTIVE DISEASES AND SCIENCES. 2017, Mar; 62(3): 567-568.
  1. 6.   IKK alpha controls ATG16L1 degradation to prevent ER stress during inflammation
  2. Diamanti, Michaela A.; Gupta, Jalaj; Bennecke, Moritz; De Oliveira, Tiago; Ramakrishnan, Mallika; Braczynski, Anne K.; Richter, Benjamin; Beli, Petra; Hu, Yinling; Saleh, Maya; Mittelbronn, Michel; Dikic, Ivan; Greten, Florian R.
  3. JOURNAL OF EXPERIMENTAL MEDICINE. 2017, 2017-02-01; 214(2): 423-437.
  1. 7.   A Distal Enhancer in Il12b Is the Target of Transcriptional Repression by the STAT3 Pathway and Requires the Basic Leucine Zipper (B-ZIP) Protein NFIL3
  2. Smith, A. M.; Qualls, J. E.; O'Brien, K.; Balouzian, L.; Johnson, P. F.; Schultz-Cherry, S.; Smale, S. T.; Murray, P. J.
  3. Journal of Biological Chemistry. 2011, Jul; 286(26): 23582-23590.
  1. 8.   Innate immune mechanisms of colitis and colitis-associated colorectal cancer
  2. Saleh, M.; Trinchieri, G.
  3. Nature Reviews Immunology. 2011, Jan; 11(1): 9-20.
  1. 9.   Mechanisms underlying gamma delta T-cell subset perturbations in SIV-infected Asian rhesus macaques
  2. Harris, L. D.; Klatt, N. R.; Vinton, C.; Briant, J. A.; Tabb, B.; Ladell, K.; Lifson, J.; Estes, J. D.; Price, D. A.; Hirsch, V. M.; Brenchley, J. M.
  3. Blood. 2010, Nov; 116(20): 4148-4157.
  1. 10.   MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18
  2. Salcedo, R.; Worschech, A.; Cardone, M.; Jones, Y.; Gyulai, Z.; Dai, R. M.; Wang, E. N.; Ma, W.; Haines, D.; O'HUigin, C.; Marincola, F. M.; Trinchieri, G.
  3. Journal of Experimental Medicine. 2010, Aug 2; 207(8): 1625-1636.
  1. 11.   Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection
  2. Klatt, N. R.; Harris, L. D.; Vinton, C. L.; Sung, H.; Briant, J. A.; Tabb, B.; Morcock, D.; McGinty, J. W.; Lifson, J. D.; Lafont, B. A.; Martin, M. A.; Levine, A. D.; Estes, J. D.; Brenchley, J. M.
  3. Mucosal Immunology. 2010, Jul; 3(4): 387-398.
  1. 12.   Successful granulocyte-colony stimulating factor treatment of Crohn's disease is associated with the appearance of circulating interleukin-10-producing T cells and increased lamina propria plasmacytoid dendritic cells
  2. Mannon, P. J.; Leon, F.; Fuss, I. J.; Walter, B. A.; Begnami, M.; Quezado, M.; Yang, Z.; Yi, C.; Groden, C.; Friend, J.; Hornung, R. L.; Brown, M.; Gurprasad, S.; Kelsall, B.; Strober, W.
  3. Clinical and Experimental Immunology. 2009 155(3): 447-456.
  1. 13.   AP-1 a target for cancer prevention
  2. Matthews, C. P.; Colburn, N. H.; Young, M. R.
  3. Current Cancer Drug Targets. 2007, Jun; 7(4): 317-324.
  1. 14.   Polymorphisms in immune function genes and risk of non-Hodgkin lymphoma: findings from the New South Wales non-Hodgkin Lymphoma Study
  2. Purdue, M. P.; Lan, Q.; Kricker, A.; Grulich, A. E.; Vajdic, C. M.; Turner, J.; Whitby, D.; Chanock, S.; Rothman, N.; Armstrong, B. K.
  3. Carcinogenesis. 2007, Mar; 28(3): 704-712.
  1. 15.   IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
  2. Kullberg, M. C.; Jankovic, D.; Feng, C. G.; Hue, S.; Gorelick, P. L.; McKenzie, B. S.; Cua, D. J.; Powrie, F.; Cheever, A. W.; Maloy, K. J.; Sher, A.
  3. Journal of Experimental Medicine. 2006, Oct; 203(11): 2485-2494.
  1. 16.   An IFNG SNP with an estrogen-like response element selectively enhances promoter expression in peripheral but not lamina propria T cells
  2. Gonsky, R.; Deem, R. L.; Bream, J. H.; Young, H. A.; Targan, S. R.
  3. Genes and Immunity. 2006, Jul; 7(5): 342-351.
  1. 17.   Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody
  2. Fuss, I. J.; Becker, C.; Yang, Z. Q.; Groden, C.; Hornung, R. L.; Heller, F.; Neurath, M. F.; Strober, W.; Mannon, P. J.
  3. Inflammatory Bowel Diseases. 2006, JAN; 12(1): 9-15.
  1. 18.   Distinct and nonredundant in vivo functions of TNF produced by T cells and macrophages/neutrophils: Protective and deleterious effects
  2. Grivennikov, S. I.; Tumanov, A. V.; Liepinsh, D. J.; Kruglov, A. A.; Marakusha, B. I.; Shakhov, A. N.; Murakami, T.; Drutskaya, L. N.; Forster, I.; Clausen, B. E.; Tessarollo, L.; Ryffel, B.; Kuprash, D. V.; Nedospasov, S. A.
  3. Immunity. 2005, JAN; 22(1): 93-104.
  1. 19.   Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis
  2. Potocnik, U.; Ferkolj, I.; Glavac, D.; Dean, M.
  3. Genes and Immunity. 2004, NOV; 5(7): 530-539.
  1. 20.   Roles for both IL-4R alpha and IL-10 in controlling inflammation in a model of inflammatory bowel disease
  2. Nagase, H.; Fogarty, T.; Arora, M.; Shanley, K.; Ward, J. M.; Franklin, C.; Kullberg, M. C.; Noben-Trauth, N.
  3. Faseb Journal. 2004 18(5, Suppl. S): A818-A818.
  1. 21.   CD2 mediates activation of the IFN-gamma intronic STAT binding region in mucosal T cells
  2. Gonsky, R.; Deem, R. L.; Young, H. A.; Targan, S. R.
  3. European Journal of Immunology. 2003 33(5): 1152-1162.
  1. 22.   Novel variants of the IL-10 receptor 1 affect inhibition of monocyte TNF-alpha production
  2. Gasche, C.; Grundtner, P.; Zwirn, P.; Reinisch, W.; Shaw, S. H.; Zdanov, A.; Sarma, U.; Williams, L. M.; Foxwell, B. M.; Gangl, A.
  3. Journal of Immunology. 2003 170(11): 5578-5582.
  1. 23.   Induction of colitis by a CD4(+) T cell clone specific for a bacterial epitope
  2. Kullberg, M. C.; Andersen, J. F.; Gorelick, P. L.; Caspar, P.; Suerbaum, S.; Fox, J. G.; Cheever, A. W.; Jankovic, D.; Sher, A.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2003 100(26): 15830-15835.
  1. 24.   Pathology of mouse models of intestinal cancer: Consensus report and recommendations
  2. Boivin, G. P.; Washington, K.; Yang, K.; Ward, J. M.; Pretlow, T. P.; Russell, R.; Besselsen, D. G.; Godfrey, V. L.; Doetschman, T.; Dove, W. F.; Pitot, H. C.; Halberg, R. B.; Itzkowitz, S. H.; Groden, J.; Coffey, R. J.
  3. Gastroenterology. 2003 124(3): 762-777.
  1. 25.   Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis
  2. Kullberg, M. C.; Jankovic, D.; Gorelick, P. L.; Caspar, P.; Letterio, J. J.; Cheever, A. W.; Sher, A.
  3. Journal of Experimental Medicine. 2002 196(4): 505-515.
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