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  1. 1.   Evaluating Demographic Representation in Clinical Trials: Use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a Test Case
  2. Ortega-Villa, Ana M; Hynes, Noreen A; Levine, Corri B; Yang, Katherine; Wiley, Zanthia; Jilg, Nikolaus; Wang,Jing; Whitaker, Jennifer A; Colombo, Christopher J; Nayak, Seema U; Kim, Hannah Jang; Iovine, Nicole M; Ince, Dilek; Cohen, Stuart H; Langer, Adam J; Wortham, Jonathan M; Atmar, Robert L; El Sahly, Hana M; Jain, Mamta K; Mehta, Aneesh K; Wolfe, Cameron R; Gomez, Carlos A; Beresnev, Tatiana; Mularski, Richard A; Paules, Catharine I; Kalil, Andre C; Branche, Angela R; Luetkemeyer, Annie; Zingman, Barry S; Voell, Jocelyn; Whitaker, Michael; Harkins, Michelle S; Davey, Richard T; Grossberg, Robert; George, Sarah L; Tapson, Victor; Short, William R; Ghazaryan, Varduhi; Benson, Constance A; Dodd, Lori E; Sweeney, Daniel A; Tomashek, Kay M
  3. Open Forum Infectious Diseases. 2023, Jun; 10(6): ofad290.
  1. 2.   Improving Patient Advocacy in NCI Scientific Steering Committees and Task Forces
  2. Bangs, Rick; Lynn, Jean M; Obot,Evelyn; Osborne, Sherill; Norris, Kim
  3. Journal of the National Cancer Institute. 2022, May 12;
  1. 3.   A Trans-Governmental Collaboration to Independently Evaluate SARS-CoV-2 Serology Assays
  2. Pinto,Ligia; Shawar, Ribhi M; O'Leary, Brendan; Kemp,Troy; Cherry, James; Thornburg, Natalie; Miller, Cheryl N; Gallagher, Pamela S; Stenzel, Timothy; Schuck, Brittany; Owen, S Michele; Kondratovich, Marina; Satheshkumar, Panayampalli S; Schuh, Amy; Lester, Sandra; Cassetti, M Cristina; Sharpless, Norman E; Gitterman, Steven; Lowy, Douglas R
  3. Microbiology Spectrum. 2022, Jan 12; e0156421.
  1. 4.   Bioequivalence assessment of high-capacity polymeric micelle nanoformulation of paclitaxel and Abraxane (R) in rodent and non-human primate models using a stable isotope tracer assay
  2. Hwang, Duhyeong; Vinod, Natasha; Skoczen,Sarah; Ramsey, Jacob D.; Snapp,Kelsie; Montgomery, Stephanie A.; Wang, Mengzhe; Lim, Chaemin; Frank, Jonathan E.; Sokolsky-Papkov, Marina; Li, Zibo; Yuan, Hong; Kabanov, Alexander; Stern,Steve
  3. Biomaterials . 2021, Nov; 278
  1. 5.   Changes in Magnetic Resonance Imaging Using the Prostate Cancer Radiologic Estimation of Change in Sequential Evaluation Criteria to Detect Prostate Cancer Progression for Men on Active Surveillance
  2. O'Connor, Luke P; Wang, Alex Z; Yerram, Nitin K; Long, Lori; Ahdoot, Michael; Lebastchi, Amir H; Gurram, Sandeep; Zeng, Johnathan; Harmon,Stephanie; Mehralivand, Sherif; Merino, Maria J; Parnes, Howard L; Choyke, Peter L; Shih, Joanna H; Wood, Bradford J; Turkbey, Baris; Pinto, Peter A
  3. European Urology Oncology. 2021, Apr ; 4(2): 227-234.
  1. 6.   Epidemiological and ES cell-based Functional Evaluation of BRCA2 Variants Identified in Families with Breast Cancer
  2. O'Sullivan,Theresa; Thirthagiri, Eswary; Chong, Chan-Eng; Stauffer,Stacey; Reid,Susan; Southon,Eileen; Hassan, Tiara; Ravichandran, Aravind; Wijaya, Eldarina; Lim, Joanna; Taib, Nur Aishah Mohd; Fadzli, Farhana; Yip, Cheng Har; Hartman, Mikael; Li, Jingmei; van Dam, Rob M; North, Susan L; Das, Ranabir; Easton, Douglas F; Biswas,Kajal; Teo, Soo-Hwang; Sharan,Shyam
  3. Human Mutation. 2021, Feb; 42(2): 200-212.
  1. 7.   Pyrrolo[2 ',3 ':3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types
  2. Spano, Virginia; Rocca, Roberta; Barreca, Marilia; Giallombardo, Daniele; Montalbano, Alessandra; Carbone, Anna; Raimondi, Maria Valeria; Gaudio, Eugenio; Bortolozzi, Roberta; Bai,Ruoli; Tassone, Pierfrancesco; Alcaro, Stefano; Hamel,Ernest; Viola, Giampietro; Bertoni, Francesco; Barraja, Paola
  3. JOURNAL OF MEDICINAL CHEMISTRY. 2020, OCT 22; 63(20): 12023-12042.
  1. 8.   Computationally Optimized SARS-CoV-2 MHC Class I and II Vaccine Formulations Predicted to Target Human Haplotype Distributions
  2. Liu, Ge; Carter, Brandon; Bricken, Trenton; Jain, Siddhartha; Viard,Mathias; Carrington,Mary; Gifford, David K
  3. Cell systems. 2020, AUG 26; 11(2): 131-144.e6.
  1. 9.   Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins
  2. Tranter, Dale; Paatero, Anja O.; Kawaguchi, Shinsaku; Kazemi, Soheila; Serrill, Jeffrey D.; Kellosalo, Juho; Vogel, Walter K.; Richter, Uwe; Mattos, Daphne R.; Wan, Xuemei; Thornburg,Chris; Oishi, Shinya; McPhail, Kerry L.; Ishmael, Jane E.; Paavilainen, Ville O.
  3. ACS CHEMICAL BIOLOGY. 2020, AUG 21; 15(8): 2125-2136.
  1. 10.   Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator
  2. Jenkins, Lisa M. Miller; Paine, Elliott L.; Deshmukh, Lalit; Nikolayevskiy, Herman; Lyons, Gaelyn C.; Scerba, Michael T.; Rosenker, Kara George; Luecke, Hans F.; Louis, John M.; Chertova,Elena; Gorelick,Robert; Ott,David; Clore, G. Marius; Appella, Daniel H.
  3. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2019, MAY 22; 141(20): 8327-8338.
  1. 11.   Establishing proof of mechanism: Assessing target modulation in early-phase clinical trials
  2. Kummar, S.; Do, K.; Coyne, G. O.; Chen, A.; Ji, J.; Rubinstein, L.; Doroshow, J. H.
  3. Seminars in Oncology. 2016, Aug; 43(4): 446-52.
  1. 12.   Advances in Breast Cancer Therapy Using Nitric Oxide and Nitroxyl Donor Agents
  2. Basudhar, Debashree; Miranda, Katrina M.; Wink, David; Ridnour, Lisa
  3. REDOX-ACTIVE THERAPEUTICS. 2016; : 377-403.
  1. 13.   Antineoplastic Agents. 548. Synthesis of lodo- and Diiodocombstatin Phosphate Prodrugs
  2. Pettit, G. R.; Rosenberg, H. J.; Dixon, R.; Knight, J. C.; Hamel, E.; Chapuis, J. C.; Pettit, R. K.; Hogan, F.; Sumner, B.; Ain, K. B.; Trickey-Platt, B.
  3. Journal of Natural Products. 2012, Mar; 75(3): 385-393.
  1. 14.   Synthesis and Antitumor Molecular Mechanism of Agents Based on Amino 2-(3 ',4 ',5 '-Trimethoxybenzoyl)benzo[b]furan: Inhibition of Tubulin and Induction of Apoptosis
  2. Romagnoli, R.; Baraldi, P. G.; Lopez-Cara, C.; Cruz-Lopez, O.; Carrion, M. D.; Salvador, M. K.; Bermejo, J.; Estevez, S.; Estevez, F.; Balzarini, J.; Brancale, A.; Ricci, A.; Chen, L. C.; Kim, J. G.; Hamel, E.
  3. Chemmedchem. 2011, Oct; 6(10): 1841-1853.
  1. 15.   Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties
  2. Flynn, B. L.; Gill, G. S.; Grobelny, D. W.; Chaplin, J. H.; Paul, D.; Leske, A. F.; Lavranos, T. C.; Chalmers, D. K.; Charman, S. A.; Kostewicz, E.; Shackleford, D. M.; Morizzi, J.; Hamel, E.; Jung, M. K.; Kremmidiotis, G.
  3. Journal of Medicinal Chemistry. 2011, Sep; 54(17): 6014-6027.
  1. 16.   N-Hydroxyethyl-4-aza-didehydropodophyllotoxin derivatives as potential antitumor agents
  2. Kumar, A.; Kumar, V.; Alegria, A. E.; Malhotra, S. V.
  3. European Journal of Pharmaceutical Sciences. 2011, Sep; 44(1-2): 21-26.
  1. 17.   Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals
  2. Bhattacharyya, S.; Dixit, M.
  3. Dalton Transactions. 2011, Jun 21; 40(23): 6112-6128.
  1. 18.   Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives
  2. Romagnoli, R.; Baraldi, P. G.; Cruz-Lopez, O.; Tolomeo, M.; Di Cristina, A.; Pipitone, R. M.; Grimaudo, S.; Balzarini, J.; Brancale, A.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry Letters. 2011, May; 21(9): 2746-2751.
  1. 19.   A West Nile Virus DNA Vaccine Utilizing a Modified Promoter Induces Neutralizing Antibody in Younger and Older Healthy Adults in a Phase I Clinical Trial
  2. Ledgerwood, J. E.; Pierson, T. C.; Hubka, S. A.; Desai, N.; Rucker, S.; Gordon, I. J.; Enama, M. E.; Nelson, S.; Nason, M.; Gu, W. J.; Bundrant, N.; Koup, R. A.; Bailer, R. T.; Mascola, J. R.; Nabel, G. J.; Graham, B. S.; Team, V. R. C. S.
  3. Journal of Infectious Diseases. 2011, May; 203(10): 1396-1404.
  1. 20.   Comparison between 3-Nitrooxyphenyl acetylsalicylate (NO-ASA) and O-2-(acetylsalicyloxymethyl)-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (NONO-ASA) as Safe Anti-Inflammatory, Analgesic, Antipyretic, Antioxidant Prodrugs
  2. Chattopadhyay, M.; Velazquez, C. A.; Pruski, A.; Nia, K. V.; Abdellatif, K. R.; Keefer, L. K.; Kashfi, K.
  3. Journal of Pharmacology and Experimental Therapeutics. 2010, Nov; 335(2): 443-450.
  1. 21.   Synthesis and Discovery of Water-Soluble Microtubule Targeting Agents that Bind to the Colchicine Site on Tubulin and Circumvent Pgp Mediated Resistance
  2. Gangjee, A.; Zhao, Y.; Lin, L.; Raghavan, S.; Roberts, E. G.; Risinger, A. L.; Hamel, E.; Mooberry, S. L.
  3. Journal of Medicinal Chemistry. 2010, Nov; 53(22): 8116-8128.
  1. 22.   The Assembly-Inducing Laulimalide/Peloruside A Binding Site on Tubulin: Molecular Modeling and Biochemical Studies with [H-3]Peloruside A
  2. Nguyen, T. L.; Xu, X. M.; Gussio, R.; Ghosh, A. K.; Hamel, E.
  3. Journal of Chemical Information and Modeling. 2010, Nov; 50(11): 2019-2028.
  1. 23.   Synthesis and Evaluation of Haloacetyl, alpha-Bromoacryloyl and Nitrooxyacetyl Benzo[b]furan and Benzo[b]thiophene Derivatives as Potent Antiproliferative Agents Against Leukemia L1210 and K562 Cells
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cara, C. L.; Casolari, A.; Hamel, E.; Fabbri, E.; Gambari, R.
  3. Letters in Drug Design & Discovery. 2010, Aug; 7(7): 476-486.
  1. 24.   Substituted 2-(3 ',4 ',5 '-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors
  2. Romagnoli, R.; Baraldi, P. G.; Carrion, M. D.; Cruz-Lopez, O.; Tolomeo, M.; Grimaudo, S.; Di Cristina, A.; Pipitone, M. R.; Balzarini, J.; Brancale, A.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry. 2010, Jul; 18(14): 5114-5122.
  1. 25.   Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization
  2. Patel, V.; Valentin, A.; Kulkarni, V.; Rosati, M.; Bergamaschi, C.; Jalah, R.; Alicea, C.; Minang, J. T.; Trivett, M. T.; Ohlen, C.; Zhao, J.; Robert-Guroff, M.; Khan, A. S.; Draghia-Akli, R.; Felber, B. K.; Pavlakis, G. N.
  3. Vaccine. 2010, Jul; 28(30): 4827-4836.
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