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  1. 1.   Creation and preclinical evaluation of a novel mussel-inspired, biomimetic, bioactive bone graft scaffold: direct comparison with Infuse bone graft using a rat model of spinal fusion
  2. Cottrill, Ethan; Pennington, Zach; Wolf,Matthew; Dirckx, Naomi; Ehresman, Jeff; Perdomo-Pantoja, Alexander; Rajkovic, Christian; Lin, Jessica; Maestas, David R; Mageau, Ashlie; Lambrechts, Dennis; Stewart, Veronica; Sciubba, Daniel M; Theodore, Nicholas; Elisseeff, Jennifer H; Witham, Timothy
  3. Journal of Neurosurgery. Spine. 2023, Mar 31; 39(1): 113-121.
  1. 2.   Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
  2. Huang, Chen; Chen, Lijun; Savage, Sara R.; Eguez, Rodrigo Vargas; Dou, Yongchao; Li, Yize; Leprevost, Felipe da Veiga; Jaehnig, Eric J.; Lei, Jonathan T.; Wen, Bo; Schnaubelt, Michael; Krug, Karsten; Song, Xiaoyu; Cieslik, Marcin; Chang, Hui-Yin; Wyczalkowski, Matthew A.; Li, Kai; Colaprico, Antonio; Li, Qing Kay; Clark, David J.; Hu, Yingwei; Cao, Liwei; Pan, Jianbo; Wang, Yuefan; Cho, Kyung-Cho; Shi, Zhiao; Liao, Yuxing; Jiang, Wen; Anurag, Meenakshi; Ji, Jiayi; Yoo, Seungyeul; Zhou, Daniel Cui; Liang, Wen-Wei; Wendl, Michael; Vats, Pankaj; Carr, Steven A.; Mani, D. R.; Zhang, Zhen; Qian, Jiang; Chen, Xi S.; Pico, Alexander R.; Wang, Pei; Chinnaiyan, Arul M.; Ketchum, Karen A.; Kinsinger, Christopher R.; Robles, Ana; An, Eunkyung; Hiltke, Tara; Mesri, Mehdi; Thiagarajan,Mathangi; Weaver, Alissa M.; Sikora, Andrew G.; Lubinski, Jan; Wierzbicka, Malgorzata; Wiznerowicz, Maciej; Satpathy, Shankha; Gillette, Michael A.; Miles, George; Ellis, Matthew J.; Omenn, Gilbert S.; Rodriguez, Henry; Boja, Emily S.; Dhanasekaran, Saravana M.; Ding, Li; Nesvizhskii, Alexey; El-Naggar, Adel K.; Chan, Daniel W.; Zhang, Hui; Zhang, Bing
  3. Cancer Cell. 2021, Mar 8; 39(3): 361-379.
  1. 3.   Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
  2. Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen,Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O'Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A.; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H.
  3. Nature Genetics. 2021, Jan; 53(1): 86-99.
  1. 4.   Single cell-derived primary rectal carcinoma cell lines reflect intratumor heterogeneity associated with treatment response
  2. Braun, Rüdiger; Anthuber, Lena; Hirsch, Daniela; Wangsa, Darawalee; Lack,Justin; McNeil, Nicole E; Heselmeyer-Haddad, Kerstin; Torres, Irianna; Wangsa, Danny; Brown, Markus A; Tubbs, Anthony; Auslander, Noam; Gertz, E Michael; Brauer, Philip R; Cam,Maggie; Sackett, Dan; Habermann, Jens K; Nussenzweig, Andre; Ruppin, Eytan; Zhang, Zhongqiu; Rosenberg, Daniel W; Ried, Thomas
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020, JUL; 26(13): 3468-3480.
  1. 5.   Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis
  2. Evrard,Yvonne; Srivastava, Anuj; Randjelovic, Jelena; Consortium, Nci PDXNet; Doroshow, James H; Dean, Dennis A; Morris, Jeffrey S; Chuang, Jeffrey H
  3. Cancer research. 2020, JUN 1; 80(11): 2286-2297.
  1. 6.   Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers
  2. Wilsker,Deborah; Barrett, Allison M.; Dull,Angie; Lawrence,Scott; Hollingshead,Melinda; Chen, Alice; Kummar, Shivaani; Parchment,Ralph; Doroshow, James H.; Kinders,Robert
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2019, MAY 15; 25(10): 3084-3095.
  1. 7.   Novel cancer gene variants and gene fusions of triple-negative breast cancers (TNBCs) reveal their molecular diversity conserved in the patient-derived xenograft (PDX) model
  2. Jung, Jaeyun; Jang, Kiwon; Ju, Jung Min; Lee, Eunji; Lee, Jong Won; Kim, Hee Jung; Kim, Jisun; Lee, Sae Byul; Ko, Beom Seok; Son, Byung Ho; Lee, Hee Jin; Gong, Gyungyup; Ahn, Sei Yeon; Choi, Jung Kyoon; Singh, Shree Ram; Chang, Suhwan
  3. Cancer Letters. 2018, Aug 01; 428: 127-138.
  1. 8.   Patterns of Sensitivity to a Panel of Drugs are highly Individualized for Undifferentiated/Unclassified Soft Tissue Sarcoma (USTS) in Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Models
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Singh, Arun S; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Unno, Michiaki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Journal of drug targeting. 2018, Jul 19; 1-25.
  1. 9.   Comparison of planar, PET and well-counter measurements of total tumor radioactivity in a mouse xenograft model.
  2. Green, Michael V; Seidel, Jurgen; Williams, Mark; Wong, Karen J; Ton, Anita; Basuli, Falguni; Choyke, Peter L; Jagoda, Elaine M
  3. Nuclear medicine and biology. 2017, Oct; 53: 29-36.
  1. 10.   Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay
  2. Ji, Jay; Zhang, Yiping; Redon, Christophe E.; Reinhold, William C.; Chen, Alice P.; Fogli, Laura K.; Holbeck, Susan L.; Parchment, Ralph; Hollingshead, Melinda; Tomaszewski, Joseph E.; Dudon, Quentin; Pommier, Yves; Doroshow, James H.; Bonner, William M.
  3. PLOS ONE. 2017, Feb 3; 12(2): e0171582.
  1. 11.   Cytotoxic Activity of Immunotoxin SS1P Is Modulated by TACE-Dependent Mesothelin Shedding
  2. Zhang, Y. J.; Chertov, O.; Zhang, J. L.; Hassan, R.; Pastan, I.
  3. Cancer Research. 2011, Sep; 71(17): 5915-5922.
  1. 12.   Multihistology, Target-Driven Pilot Trial of Oral Topotecan as an Inhibitor of Hypoxia-Inducible Factor-1 alpha in Advanced Solid Tumors
  2. Kummar, S.; Raffeld, M.; Juwara, L.; Horneffer, Y.; Strassberger, A.; Allen, D.; Steinberg, S. M.; Rapisarda, A.; Spencer, S. D.; Figg, W. D.; Chen, X. H.; Turkbey, I. B.; Choyke, P.; Murgo, A. J.; Doroshow, J. H.; Melillo, G.
  3. Clinical Cancer Research. 2011, Aug; 17(15): 5123-5131.
  1. 13.   Lymphoid-Specific Helicase (HELLS) Is Essential for Meiotic Progression in Mouse Spermatocytes
  2. Zeng, W. X.; Baumann, C.; Schmidtmann, A.; Honaramooz, A.; Tang, L.; Bondareva, A.; Dores, C.; Fan, T.; Xi, S. C.; Geiman, T.; Rathi, R.; de Rooij, D.; De La Fuente, R.; Muegge, K.; Dobrinski, I.
  3. Biology of Reproduction. 2011, Jun; 84(6): 1235-1241.
  1. 14.   Insights into the effect of nitric oxide and its metabolites nitrite and nitrate at inhibiting neointimal hyperplasia
  2. Vavra, A. K.; Havelka, G. E.; Martinez, J.; Lee, V. R.; Fu, B.; Jiang, Q.; Keefer, L. K.; Kibbe, M. R.
  3. Nitric Oxide-Biology and Chemistry. 2011, Jun; 25(1): 22-30.
  1. 15.   Poly(diol-co-citrate)s as Novel Elastomeric Perivascular Wraps for the Reduction of Neointimal Hyperplasia
  2. Serrano, M. C.; Vavra, A. K.; Jen, M.; Hogg, M. E.; Murar, J.; Martinez, J.; Keefer, L. K.; Ameer, G. A.; Kibbe, M. R.
  3. Macromolecular Bioscience. 2011, May; 11(5): 700-709.
  1. 16.   Tailored synthesis of nitric oxide-releasing polyurethanes using O-2-protected diazeniumdiolated chain extenders
  2. Reynolds, M. M.; Saavedra, J. E.; Showalter, B. M.; Valdez, C. A.; Shanklin, A. P.; Oh, B. K.; Keefer, L. K.; Meyerhoff, M. E.
  3. Journal of Materials Chemistry. 2010, Mar 21; 20(15): 3107-3114.
  1. 17.   Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition
  2. Rapisarda, A.; Hollingshead, M.; Uranchimeg, B.; Bonomi, C. A.; Borgel, S. D.; Carter, J. P.; Gehrs, B.; Raffeld, M.; Kinders, R. J.; Parchment, R.; Anver, M. R.; Shoemaker, R. H.; Melillo, G.
  3. Molecular Cancer Therapeutics. 2009 8(7): 1867-1877.
  1. 18.   Hypoxia-inducible factor-1 target genes as indicators of tumor vessel response to vascular endothelial growth factor inhibition
  2. Dang, D. T.; Chun, S. Y.; Burkitt, K.; Abe, M.; Chen, S.; Havre, P.; Mabjeesh, N. J.; Heath, E. I.; Vogelzang, N. J.; Cruz-Correa, M.; Blayney, D. W.; Ensminger, W. D.; Croix, B. S.; Dang, N. H.; Dang, L. H.
  3. Cancer Research. 2008 68(6): 1872-1880.
  1. 19.   Nitric oxide and nanotechnology: A novel approach to inhibit neointimal hyperplasia
  2. Kapadia, M. R.; Chow, L. W.; Tsihlis, N. D.; Ahanchi, S. S.; Hrabie, J. A.; Murar, J.; Martinez, J.; Popowich, D. A.; Jiang, Q.; Hrabie, J. A.; Saavedra, J. E.; Keefer, L. K.; HUlvat, J. F.; Stupp, S. I.; Kibbe, M. P.
  3. Journal of Vascular Surgery. 2008 47(1): 173-182.
  1. 20.   Natural killer cells recruited into lymph nodes inhibit alloreactive T-cell activation through perforin-mediated killing of donor allogeneic dendritic cells
  2. Laffont, S.; Seillet, C.; Ortaldo, J.; Coudert, J. D.; Guery, J. C.
  3. Blood. 2008 112(3): 661-671.
  1. 21.   Nitric oxide releasing polyurethanes with covalently linked diazeniumdiolated secondary amines
  2. Reynolds, M. M.; Hrabie, J. A.; Oh, B. K.; Politis, J. K.; Citro, M. L.; Keefer, L. K.; Meyerhoff, M. E.
  3. Biomacromolecules. 2006, Mar; 7(3): 987-994.
  1. 22.   PABA/NO as an anticancer lead: Analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity
  2. Saavedra, J. E.; Srinivasan, A.; Buzard, G. S.; Davies, K. M.; Waterhouse, D. J.; Inami, K.; Wilde, T. C.; Citro, M. L.; Cuellar, M.; Deschamps, J. R.; Parrish, D.; Shami, P. J.; Findlay, V. J.; Townsend, D. M.; Tew, K. D.; Singh, S.; Jia, L.; Ji, X. H.; Keefer, L. K.
  3. Journal of Medicinal Chemistry. 2006, FEB 9; 49(3): 1157-1164.
  1. 23.   Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation
  2. Welniak, L. A.; Kuprash, D. V.; Tumanov, A. V.; Panoskaltsis-Mortari, A.; Blazar, B. R.; Sun, K.; Nedospasov, S. A.; Murphy, W. J.
  3. Blood. 2006, JAN 1; 107(1): 410-412.
  1. 24.   Phase I trial of temozolomide plus O-6-benzylguanine for patients with recurrent or progressive malignant glioma
  2. Quinn, J. A.; Desjardins, A.; Weingart, J.; Brem, H.; Dolan, M. E.; Delaney, S. M.; Vredenburgh, J.; Rich, J.; Friedman, A. H.; Reardon, D. A.; Sampson, J. H.; Pegg, A. E.; Moschel, R. C.; Birch, R.; McLendon, R. E.; Provenzale, J. M.; Gururangan, S.; Dancey, J. E.; Maxwell, J.; Tourt-Uhlig, S.; Herndon, J. E.; Bigner, D. D.; Friedman, H. S.
  3. Journal of Clinical Oncology. 2005, OCT 1; 23(28): 7178-7187.
  1. 25.   In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative
  2. Hollingshead, M.; Alley, M.; Burger, A. M.; Borgel, S.; Pacula-Cox, C.; Fiebig, H. H.; Sausville, E. A.
  3. Cancer Chemotherapy and Pharmacology. 2005, AUG; 56(2): 115-125.
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