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  1. 1.   Revealing the mechanism of action of a first-in-class covalent inhibitor of KRASG12C (ON) and other functional properties of oncogenic KRAS by 31P NMR
  2. Sharma,Alok; Pei, Jun; Yang, Yue; Dyba,Marcin; Smith,Brian; Rabara,Dana; Larsen,Erik; Lightstone, Felice C; Esposito,Dom; Stephen,Andy; Wang, Bin; Beltran, Pedro J; Wallace, Eli; Nissley,Dwight; McCormick, Frank; Maciag,Anna
  3. The Journal of Biological Chemistry. 2024, Jan 16; 300(2): 105650.
  1. 2.   NMR H-1, C-13, N-15 backbone resonance assignments of the T35S and oncogenic T35S/Q61L mutants of human KRAS4b in the active, GppNHp-bound conformation
  2. Sharma, Alok K.; Dyba, Marcin; Tonelli, Marco; Smith, Brian; Gillette, William K.; Esposito, Dominic; Nissley, Dwight; McCormick, Frank; Maciag, Anna E.
  3. Biomolecular NMR Assignments. 2021, Oct 22;
  1. 3.   The protein kinase MAP3K19 phosphorylates MAP2Ks and thereby activates ERK and JNK kinases and increases viability of KRAS-mutant lung cancer cells
  2. Hoang, Van T.; Nyswaner,Katherine; Torres-Ayuso,Pedro; Brognard,John
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, JUN 19; 295(25): 8470-8479.
  1. 4.   Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer
  2. Sherekar,Mukul; Han, Sae-Won; Ghirlando, Rodolfo; Messing,Simon; Drew,Matt; Rabara,Dana; Waybright,Tim; Juneja, Puneet; O'Neill, Hugh; Stanley, Christopher B; Bhowmik, Debsindhu; Ramanathan, Arvind; Subramaniam,Sriram; Nissley,Dwight; Gillette,Bill; McCormick, Frank; Esposito,Dom
  3. The Journal of biological chemistry. 2020, JAN 24; 295(4): 1105-1119.
  1. 5.   Flexible-Body Motions of Calmodulin and the Farnesylated Hypervariable Region Yield a High-Affinity Interaction Enabling K-Ras4B Membrane Extraction.
  2. Jang, Hyunbum; Banerjee, Avik; Chavan, Tanmay; Gaponenko, Vadim; Nussinov, Ruth
  3. The Journal of biological chemistry. 2017, Jul 28; 292(30): 12544-12559.
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