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  1. 1.   Regulation of RAF family kinases: new insights from recent structural and biochemical studies
  2. Spencer-Smith, Russell; Morrison,Deborah
  3. Biochemical Society Transactions. 2024, June 26; 52(3): 1061-1069.
  1. 2.   Inhibition of HSP 90 is associated with potent anti-tumor activity in Papillary Renal Cell Carcinoma
  2. Pahwa, Roma; Dubhashi, Janhavi; Singh, Anand; Jailwala, Parthav; Lobanov,Alexei; Thomas, Craig J; Ceribelli, Michele; Wilson, Kelli; Ricketts, Christopher J; Vocke, Cathy D; Wells, Catherine; Bottaro, Donald P; Linehan, W Marston; Neckers, Len; Srinivasan, Ramaprasad
  3. Journal of Experimental & Clinical Cancer Research : CR. 2022, Jun 27; 41(1): 208.
  1. 3.   ß-hCG induced mutant BRCA1 ignites drug resistance in susceptible breast tissue
  2. Sengodan,Satheesh; Hemalatha, Sreelatha K; Nadhan, Revathy; Somanathan, Thara; Mathew, Arun Peter; Chil, Arkadiusz; Kopczynski, Janusz; Nair, Rakesh Sathish; Kumar, Jerald Mahesh; Srinivas, Priya
  3. Carcinogenesis. 2019, Nov; 40(11): 1415-1426.
  1. 4.   First-in-human study of the epichaperome inhibitor PU-H71: clinical results and metabolic profile
  2. Speranza, Giovanna; Anderson, Larry; Chen, Alice P; Do, Khanh; Eugeni, Michelle; Weil, Marcie; Rubinstein, Larry; Majerova, Eva; Collins, Jerry; Horneffer, Yvonne; Juwara, Lamin; Zlott, Jennifer; Bishop, Rachel; Conley, Barbara A; Streicher, Howard; Tomaszewski, Joseph; Doroshow, James H; Kummar, Shivaani
  3. Investigational New Drugs. 2018, Apr; 36(2): 230-239.
  1. 5.   Methoxychalcone inhibitors of androgen receptor translocation and function
  2. Kim, Y. S.; Kumar, V.; Lee, S.; Iwai, A.; Neckers, L.; Malhotra, S. V.; Trepel, J. B.
  3. Bioorganic & Medicinal Chemistry Letters. 2012, Mar; 22(5): 2105-2109.
  1. 6.   Determination of PF-04928473 in human plasma using liquid chromatography with tandem mass spectrometry
  2. Jain, L.; Gardner, E. R.; Venitz, J.; Giaccone, G.; Houk, B. E.; Figg, W. D.
  3. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 2010, Nov; 878(30): 3187-3192.
  1. 7.   Phase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignancies
  2. Kummar, S.; Gutierrez, M. E.; Gardner, E. R.; Chen, X. H.; Figg, W. D.; Zajac-Kaye, M.; Chen, M.; Steinberg, S. M.; Muir, C. A.; Yancey, M. A.; Horneffer, Y. R.; Juwara, L.; Melillo, G.; Ivy, S. P.; Merino, M.; Neckers, L.; Steeg, P. S.; Conley, B. A.; Giaccone, G.; Doroshow, J. H.; Murgo, A. J.
  3. European Journal of Cancer. 2010, Jan; 46(2): 340-347.
  1. 8.   New arylthioindoles: Potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies
  2. De Martino, G.; Edler, M. C.; La Regina, G.; Coluccia, A.; Barbera, M. C.; Barrow, D.; Nicholson, R. I.; Chiosis, G.; Brancale, A.; Hamel, E.; Artico, M.; Silvestri, R.
  3. Journal of Medicinal Chemistry. 2006, FEB 9; 49(3): 947-954.
  1. 9.   In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative
  2. Hollingshead, M.; Alley, M.; Burger, A. M.; Borgel, S.; Pacula-Cox, C.; Fiebig, H. H.; Sausville, E. A.
  3. Cancer Chemotherapy and Pharmacology. 2005, AUG; 56(2): 115-125.
  1. 10.   Enhanced tumor cell radiosensitivity and abrogation of G(2) and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin
  2. Bull, E. E. A.; Dote, H.; Brady, K. J.; Burgan, W. E.; Carter, D. J.; Cerra, M. A.; Oswald, K. A.; Hollingshead, M. G.; Camphausen, K.; Tofilon, P. J.
  3. Clinical Cancer Research. 2004, DEC 1; 10(23): 8077-8084.
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