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  1. 1.   Hypoxia, stem cells and bone tumor
  2. Zeng, W.; Wan, R.; Zheng, Y. H.; Singh, S. R.; Wei, Y. Y.
  3. Cancer Letters. 2011, Dec; 313(2): 129-136.
  1. 2.   Inactivation of the von Hippel-Lindau tumor suppressor leads to selective expression of a human endogenous retrovirus in kidney cancer
  2. Cherkasova, E.; Malinzak, E.; Rao, S.; Takahashi, Y.; Senchenko, V. N.; Kudryavtseva, A. V.; Nickerson, M. L.; Merino, M.; Hong, J. A.; Schrump, D. S.; Srinivasan, R.; Linehan, W. M.; Tian, X.; Lerman, M. I.; Childs, R. W.
  3. Oncogene. 2011, Nov; 30(47): 4697-4706.
  1. 3.   RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
  2. Lipkowitz, S.; Weissman, A. M.
  3. Nature Reviews Cancer. 2011, Sep; 11(9): 629-643.
  1. 4.   A New Hypoxia Inducible Factor-2 Inhibitory Pyrrolinone Alkaloid from Roots and Stems of Piper sarmentosum
  2. Bokesch, H. R.; Gardella, R. S.; Rabe, D. C.; Bottaro, D. P.; Linehan, W. M.; McMahon, J. B.; McKee, T. C.
  3. Chemical & Pharmaceutical Bulletin. 2011, Sep; 59(9): 1178-1179.
  1. 5.   The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling
  2. Ping, Y. F.; Yao, X. H.; Jiang, J. Y.; Zhao, L. T.; Yu, S. C.; Jiang, T.; Lin, M. C. M.; Chen, J. H.; Wang, B.; Zhang, R.; Cui, Y. H.; Qian, C.; Wang, J. M.; Bian, X. W.
  3. Journal of Pathology. 2011, Jul; 224(3): 344-354.
  1. 6.   ASPS-1, A Novel Cell Line Manifesting Key Features of Alveolar Soft Part Sarcoma
  2. Kenney, S.; Vistica, D. T.; Stockwin, L. H.; Burkett, S.; Hollingshead, M. G.; Borgel, S. D.; Butcher, D. O.; Schrump, D. S.; Shoemaker, R. H.
  3. Journal of Pediatric Hematology Oncology. 2011, Jul; 33(5): 360-368.
  1. 7.   Large-scale Exploration of Gene-Gene Interactions in Prostate Cancer Using a Multistage Genome-wide Association Study
  2. Ciampa, J.; Yeager, M.; Amundadottir, L.; Jacobs, K.; Kraft, P.; Chung, C.; Wacholder, S.; Yu, K.; Wheeler, W.; Thun, M. J.; Divers, W. R.; Gapstur, S.; Albanes, D.; Virtamo, J.; Weinstein, S.; Giovannucci, E.; Willett, W. C.; Cancel-Tassin, G.; Cussenot, O.; Valeri, A.; Hunter, D.; Hoover, R.; Thomas, G.; Chanock, S.; Chatterjee, N.
  3. Cancer Research. 2011, May; 71(9): 3287-3295.
  1. 8.   Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC
  2. Stockwin, L. H.; Yu, S. X.; Borgel, S.; Hancock, C.; Wolfe, T. L.; Phillips, L. R.; Hollingshead, M. G.; Newton, D. L.
  3. International Journal of Cancer. 2010, Dec; 127(11): 2510-2519.
  1. 9.   The tumour suppressor C/EBP delta inhibits FBXW7 expression and promotes mammary tumour metastasis
  2. Balamurugan, K.; Wang, J. M.; Tsai, H. H.; Sharan, S.; Anver, M.; Leighty, R.; Sterneck, E.
  3. Embo Journal. 2010, Dec; 29(24): 4106-4117.
  1. 10.   Structural analysis of cytokines comprising the IL-10 family
  2. Zdanov, A.
  3. Cytokine & Growth Factor Reviews. 2010, Oct; 21(5): 325-330.
  1. 11.   Aminoflavone, a Ligand of the Aryl Hydrocarbon Receptor, Inhibits HIF-1 alpha Expression in an AhR-Independent Fashion
  2. Terzuoli, E.; Puppo, M.; Rapisarda, A.; Uranchimeg, B.; Cao, L. A.; Burger, A. M.; Ziche, M.; Melillo, G.
  3. Cancer Research. 2010, Sep 1; 70(17): 6837-6848.
  1. 12.   Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion
  2. Santhanam, A. N.; Baker, A. R.; Hegamyer, G.; Kirschmann, D. A.; Colburn, N. H.
  3. Oncogene. 2010, Jul; 29(27): 3921-3932.
  1. 13.   Development of HIF-1 inhibitors for cancer therapy
  2. Onnis, B.; Rapisarda, A.; Melillo, G.
  3. Journal of Cellular and Molecular Medicine. 2009, Sep; 13(9A): 2780-6.
  1. 14.   Cytotoxic and HIF-1alpha inhibitory compounds from Crossosoma bigelovii
  2. Klausmeyer, P.; Zhou, Q.; Scudiero, D. A.; Uranchimeg, B.; Melillo, G.; Cardellina, J. H.; Shoemaker, R. H.; Chang, C. J.; McCloud, T. G.
  3. Journal of Natural Products. 2009, May 22; 72(5): 805-12.
  1. 15.   Metal Ions-Stimulated Iron Oxidation in Hydroxylases Facilitates Stabilization of HIF-1 alpha Protein
  2. Kaczmarek, M.; Cachau, R. E.; Topol, I. A.; Kasprzak, K. S.; Ghio, A.; Salnikow, K.
  3. Toxicological Sciences. 2009 107(2): 394-403.
  1. 16.   Therapeutic Vulnerability of an In Vivo Model of Alveolar Soft Part Sarcoma (ASPS) to Antiangiogenic Therapy
  2. Vistica, D. T.; Hollingshead, M.; Borgel, S. D.; Kenney, S.; Stockwin, L. H.; Raffeld, M.; Schrump, D. S.; Burkett, S.; Stone, G.; Butcher, D. O.; Shoemaker, R. H.
  3. Journal of Pediatric Hematology Oncology. 2009 31(8): 561-570.
  1. 17.   Differential involvement of vascular endothelial growth factor in the survival of hypoxic colon cancer cells
  2. Calvani, M.; Trisciuoglio, D.; Bergamaschi, C.; Shoemaker, R. H.; Melillo, G.
  3. Cancer Research. 2008 68(1): 285-291.
  1. 18.   Transcriptome of hypoxic immature dendritic cells: Modulation of chemokine/receptor expression
  2. Ricciardi, A.; Elia, A. R.; Cappello, P.; Puppo, M.; Vann, C.; Fardin, P.; Eva, A.; Munroe, D.; Wu, X. L.; Giovarelli, M.; Varesio, L.
  3. Molecular Cancer Research. 2008 6(2): 175-185.
  1. 19.   UVC inhibits HIF-1 alpha protein translation by a DNA damage- and topoisomerase I-independent pathway
  2. Rapisarda, A.; Melillo, G.
  3. Oncogene. 2007, Oct; 26(48): 6875-6884.
  1. 20.   Expression of hypoxia-inducible factor 1 alpha, hypoxia-inducible factor 2 alpha, and von Hippel-Lindau protein in epitheLiaL ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1 alpha is an independent prognostic factor in ovarian carcinoma
  2. Osada, R.; Horiuchi, A.; Kikuchi, N.; Yoshida, J.; Hayashi, A.; Ota, M.; Katsuyama, Y.; Melilo, G.; Konishi, I.
  3. Human Pathology. 2007, Sep; 38(9): 1310-1320.
  1. 21.   Targeting hypoxia cell signaling for cancer therapy
  2. Melillo, G.
  3. Cancer and Metastasis Reviews. 2007, Jun; 26(2): 341-352.
  1. 22.   The role of ascorbate in the modulation of HIF-1 alpha protein and HIF-dependent transcription by chromium(VI) and nickel(II)
  2. Kaczmarek, M.; Timofeeva, O. A.; Karaczyn, A.; Malyguine, A.; Kasprzak, K. S.; Salnikow, K.
  3. Free Radical Biology and Medicine. 2007, Apr; 42(8): 1246-1257.
  1. 23.   Identification of a new natural camptothecin analogue in targeted screening for HIF-1 alpha inhibitors
  2. Klausmeyer, P.; McCloud, T. G.; Melillo, G.; Scudiero, D. A.; Cardellina, J. H.; Shoemaker, R. H.
  3. Planta Medica. 2007, Jan; 73(1): 49-52.
  1. 24.   Decreased brain damage and curtailed inflammation in transcription factor CCAAT/enhancer binding protein beta knockout mice following transient focal cerebral ischemia
  2. Kapadia, R.; Tureyen, K.; Bowen, K. K.; Kalluri, H.; Johnson, P. F.; Vemuganti, R.
  3. Journal of Neurochemistry. 2006, Sep; 98(6): 1718-1731.
  1. 25.   Expression of hypoxia inducible factor-1 alpha and 2 alpha in genetically distinct early renal cortical tumors
  2. Kim, C. M.; Vocke, C.; Torres-Cabala, C.; Yang, Y. F.; Schmidt, L.; Walther, M.; Linehan, W. M.
  3. Journal of Urology. 2006, May; 175(5): 1908-1914.
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