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  1. 1.   The Janus kinase 1 is critical for pancreatic cancer initiation and progression
  2. Shrestha, Hridaya; Rädler, Patrick D; Dennaoui, Rayane; Wicker, Madison N; Rajbhandari, Nirakar; Sun, Yunguang; Peck, Amy R; Vistisen, Kerry; Triplett, Aleata A; Beydoun, Rafic; Sterneck,Esta; Saur, Dieter; Rui, Hallgeir; Wagner, Kay-Uwe
  3. Cell Reports. 2024, May 10; 43(5): 114202.
  1. 2.   Treatment with a JAK1/2 inhibitor ameliorates murine autoimmune cholangitis induced by IFN overexpression
  2. Shao, Tihong; Leung, Patrick S C; Zhang, Weici; Tsuneyama, Koichi; Ridgway, William M; Young,Howard; Shuai, Zongwen; Ansari, Aftab A; Gershwin, M Eric
  3. Cellular & Molecular Immunology. 2022, Aug 30;
  1. 3.   The promise of Janus kinase inhibitors in the treatment of hematological malignancies
  2. Senkevitch, Emilee; Durum, Scott
  3. Cytokine. 2017, Oct; 98(Special Issue): 33-41.
  1. 4.   Transforming Growth Factor-ß (TGF-ß) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway.
  2. Tang, Liu-Ya; Heller, Mary; Meng, Zhaojing; Yu, Li-Rong; Tang, Yi; Zhou, Ming; Zhang, Ying E
  3. The Journal of biological chemistry. 2017, Mar 10; 292(10): 4302-4312.
  1. 5.   Crystal Structure of a Complex of the Intracellular Domain of Interferon lambda Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1
  2. Zhang, D.; Wlodawer, A.; Lubkowski, J.
  3. Journal of Molecular Biology. 2016, 2016-11-20; 428(23): 4651-4668.
  1. 6.   Transcriptomic analysis of an in vitro murine model of ovarian carcinoma: Functional similarity to the human disease and identification of prospective tumoral markers and targets
  2. Urzua, U.; Roby, K. F.; Gangi, L. M.; Cherry, J. M.; Powell, J. I.; Munroe, D. J.
  3. Journal of Cellular Physiology. 2006, MAR; 206(3): 594-602.
  1. 7.   Tyrosine phosphorylation of the Janus kinase 2 activation loop is essential for a high-activity catalytic state but dispensable for a basal catalytic state
  2. Chatti, K.; Farrar, W. L.; Duhe, R. J.
  3. Biochemistry. 2004 43(14): 4272-4283.
  1. 8.   Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways
  2. Nagy, Z. S.; Wang, Y. L.; Erwin-Cohen, R. A.; Aradi, J.; Monia, B.; Wang, L. H.; Stepkowski, S. M.; Rui, H.; Kirken, R. A.
  3. Journal of Leukocyte Biology. 2002 72(4): 819-828.
  1. 9.   IL-2 signaling in human monocytes involves the phosphorylation and activation of p59(hck)
  2. Bosco, M. C.; Curiel, R. E.; Zea, A. H.; Malabarba, M. G.; Ortaldo, J. R.; Espinoza-Delgado, I.
  3. Journal of Immunology. 2000 164(9): 4575-4585.
  1. 10.   Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: Role of receptor-associated chains and locus accessibility
  2. Durum, S. K.; Candeias, S.; Nakajima, H.; Leonard, W. J.; Baird, A. M.; Berg, L. J.; Muegge, K.
  3. Journal of Experimental Medicine. 1998 188(12): 2233-2241.
  1. 11.   Mechanisms of Cytokine Signal Transduction - Il-2, Il-4 and Prolactin As Hematopoietin Receptor Models
  2. Kirken, R. A.; Evans, G. A.; Duhe, R. J.; Dasilva, L.; Malabarba, M. G.; Erwin, R. A.; Farrar, W. L.
  3. Veterinary Immunology and Immunopathology. 1998 63(1-2): 27-36.
  1. 12.   Microinjected Cdna Encoding Jak2 Protein-Tyrosine Kinase Induces Dna Synthesis in Nih 3t3 Cells
  2. Smith, M. R.; Duhe, R. J.; Liu, Y. L.; Farrar, W. L.
  3. Febs Letters. 1997 408(3): 327-330.
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