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  1. 1.   Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine
  2. Maciag,Anna; Yang, Yue; Sharma,Alok; Turner,David; Dehart,Caroline; Abdelkarim, Hazem; Fan,Lixin; Smith,Brian; Kumari,Vandana; Dyba,Marcin; Rigby,Megan; Castillo Badillo,Jean; Adams, Lauren; Fornelli, Luca; Fox, Stephen; Brafman, Alla; Turbyville,Thomas; Gillette,William; Messing,Simon; Agamasu, Constance; Wolfe, Andrew L; Gysin, Stephan; Chan, Albert H; Simanshu,Dhirendra; Esposito,Dominic; Chertov,Oleg; Stephen,Andrew; Arkin, Michelle; Renslo, Adam; Kelleher, Neil L; Gaponenko, Vadim; Lightstone, Felice C; Nissley,Dwight; McCormick, Frank
  3. Proceedings of the National Academy of Sciences of the United States of America. 2025, May 13; 122(19): e2410766122.
  1. 2.   Producing recombinant proteins in Vibrio natriegens
  2. Smith,Matthew; Hernández, José Sánchez; Messing,Simon; Ramakrishnan,Nitya; Higgins,Brianna; Mehalko,Jennifer; Perkins,Shelley; Wall,Vanessa; Grose,Carissa; Frank,Peter; Cregger, Julia; Le,Vi; Johnson,Adam; Sherekar, Mukul; Pagonis,Morgan; Drew,Matt; Hong,Min; Widmeyer, Stephanie R T; Denson,John-Paul; Snead,Kelly; Poon,Ivy; Waybright,Tim; Champagne, Allison; Esposito,Dom; Jones,Jane; Taylor,Troy; Gillette,Bill
  3. Microbial Cell Factories. 2024, Jul 24; 23(1): 208.
  1. 3.   Revealing KRas4b topology on the membrane surface
  2. Shree, Shweta; McLean, Mark A; Stephen,Andy; Sligar, Stephen G
  3. Biochemical and Biophysical Research Communications. 2023, Oct 20; 678: 122-127.
  1. 4.   Unveiling the Dynamics of KRAS4b on Lipid Model Membranes
  2. Lopez, Cesar A.; Agarwal, Animesh; Van,Que; Stephen,Andy; Gnanakaran, S.
  3. Journal of Membrane Biology. 2021, Apr; 254(2): 201-216.
  1. 5.   Nucleotide-Specific Autoinhibition of Full-Length K-Ras4B Identified by Extensive Conformational Sampling
  2. Dudas, Balint; Merzel, Franci; Jang,Hyunbum; Nussinov,Ruth; Perahia, David; Balog, Erika
  3. Frontiers in molecular biosciences. 2020, JUL 10; 7: 145.
  1. 6.   Calmodulin and IQGAP1 activation of PI3K alpha and Akt in KRAS, HRAS and NRAS-driven cancers
  2. Nussinov, Ruth; Zhang, Mingzhen; Tsai, Chung-Jung; Jang, Hyunbum
  3. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 2018, Jun; 0925-4439:(6, Part B, Special Issue): 2304-2314.
  1. 7.   Raf-1 Cysteine-Rich Domain Increases the Affinity of K-Ras/Raf at the Membrane, Promoting MAPK Signaling
  2. Li, Shuai; Jang, Hyunbum; Zhang, Jian; Nussinov, Ruth
  3. Structure . 2018, Mar 6; 26(3): 513-+.
  1. 8.   Oncogenic KRas mobility in the membrane and signaling response
  2. Nussinov, Ruth; Tsai, Chung-Jung; Jang, Hyunbum
  3. Seminars in Cancer Biology. 2018, Feb; 1044-579X: 109-113.
  1. 9.   FLAG-KRAS4B as a Model System for KRAS4B Proteoform and PTM Evaluation by Mass Spectrometry
  2. D'Ippolito,Robert; Scheidemantle,Grace; Smith,Brian; Powell,Katie; Eury,Scott; Neish, Abigail; Mehalko,Jennifer; Beaumont,Lauren; Fer,Nicole; Wall,Vanessa; Burgan,William; Maciag,Anna; Esposito,Dom; Dehart,Caroline
  3. Methods in Molecular Biology (Clifton, N.J.). 2024 2797: 299-322.
  1. 10.   Production of Isotopically Labeled KRAS4b
  2. Taylor,Troy; Gillette,Bill
  3. Methods in Molecular Biology (Clifton, N.J.). 2024 2797: 23-34.
  1. 11.   Determining KRAS4B-Targeting Compound Specificity by Top-Down Mass Spectrometry
  2. D'Ippolito,Robert; Scheidemantle,Grace; Rabara,Dana; Abreu Blanco, Maria; Ramakrishnan,Nitya; Widmeyer, Stephanie R T; Messing,Simon; Turner,David; Maciag,Anna; Stephen,Andy; Esposito,Dom; McCormick, Frank; Nissley,Dwight; Dehart,Caroline
  3. Methods in Molecular Biology (Clifton, N.J.). 2024 2823: 291-310.
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