Skip NavigationSkip to Content

NCI at Frederick Scientific Publications Advanced Search

Search

  1. NCI-F Publications

  2. Return to Quick Search
Search
  2. Year Published:

Your search returned 68 results.
User Information
Export Records
  1. 1.   Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance
  2. Zhang,Wengang; Bradburn, Devin; Heidebrink, Gretchen; Liu, Yonglan; Jang,Hyunbum; Nussinov,Ruth; Kõivomägi, Mardo
  3. Journal of Molecular Biology. 2025, Mar 31; 169121.
  1. 2.   Slower CDK4 and faster CDK2 activation in the cell cycle
  2. Zhang,Wengang; Liu,Yonglan; Jang,Hyunbum; Nussinov,Ruth
  3. Structure (London, England : 1993). 2024, Apr 23;
  1. 3.   Cancer and Autism: How PTEN Mutations Degrade Function at the Membrane and Isoform Expression in the Human Brain
  2. Jang,Hyunbum; Chen, Jiaye; Iakoucheva, Lilia M; Nussinov,Ruth
  3. Journal of Molecular Biology. 2023, Dec 15; 435(24): 168354.
  1. 4.   SHP2 clinical phenotype, cancer, or RASopathies, can be predicted by mutant conformational propensities
  2. Liu,Yonglan; Zhang,Wengang; Jang,Hyunbum; Nussinov,Ruth
  3. Cellular and Molecular Life Sciences : CMLS. 2023, Dec 12; 81(1): 5.
  1. 5.   Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity
  2. Tocco, Graziella; Canton, Serena; Laus, Antonio; Caboni, Pierluigi; Le Grice, Stuart F J; Tramontano, Enzo; Esposito, Francesca
  3. Molecules (Basel, Switzerland). 2023, Sep 19; 28(18):
  1. 6.   Specific inhibition of an anticancer target, polo-like kinase 1, by allosterically dismantling its mechanism of substrate recognition
  2. Park, Jung-Eun; Kirsch, Klara; Lee, Hobin; Oliva, Paola; Ahn, Jong Il; Ravishankar, Harsha; Zeng, Yan; Fox,Stephen; Kirby, Samuel A; Badhwar, Pooja; Andresson,Thorkell; Jacobson, Kenneth A; Lee, Kyung S
  3. Proceedings of the National Academy of Sciences of the United States of America. 2023, Aug 29; 120(35): e2305037120.
  1. 7.   Allosteric regulation of autoinhibition and activation of c-Abl
  2. Liu,Yonglan; Zhang,Mingzhen; Tsai,Chung-Jung; Jang,Hyunbum; Nussinov,Ruth
  3. Computational and Structural Biotechnology Journal. 2022 20: 4257-4270.
  1. 8.   The mechanism of Raf activation through dimerization
  2. Zhang,Mingzhen; Maloney,Ryan; Jang,Hyunbum; Nussinov,Ruth
  3. Chemical Science. 2021, Dec 08; 12(47): 15609-15619.
  1. 9.   The Role of Conformational Dynamics in the Recognition and Regulation of Ubiquitination
  2. Khago, Domarin; Fucci,Ian; Byrd,Robert
  3. Molecules (Basel, Switzerland). 2020, Dec 15; 25(24):
  1. 10.   Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs)
  2. He, Yanan; Agnihotri, Pragati; Rangarajan, Sneha; Chen, Yihong; Kerzic, Melissa C.; Ma, Buyong; Nussinov,Ruth; Mariuzza, Roy A.; Orban, John
  3. JOURNAL OF MOLECULAR BIOLOGY. 2020, Dec 4; 432(24):
  1. 11.   Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H
  2. Tocco, Graziella; Esposito, Francesca; Caboni, Pierluigi; Laus, Antonio; Beutler,John; Wilson,Jennifer; Corona, Angela; Le Grice,Stuart; Tramontano, Enzo
  3. Journal of enzyme inhibition and medicinal chemistry. 2020, Dec; 35(1): 1953-1963.
  1. 12.   Autoinhibition can identify rare driver mutations and advise pharmacology
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020, Jan; 34(1): 16-29.
  1. 13.   Does Ras Activate Raf and PI3K Allosterically?
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. Frontiers in oncology. 2019, Nov 15; 9
  1. 14.   Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate
  2. Roy, Neeladri Sekhar; Jian, Xiaoying; Soubias,Olivier; Zhai, Peng; Hall, Jessica R.; Dagher, Jessica N.; Coussens, Nathan P.; Jenkins, Lisa M.; Luo, Ruibai; Akpan, Itoro O.; Hall, Matthew D.; Byrd,Robert; Yohe, Marielle E.; Randazzo, Paul A.
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2019, NOV 15; 294(46): 17354-17370.
  1. 15.   Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome
  2. Chittori, Sagar; Hong, Jingjun; Bai, Yawen; Subramaniam,Sriram
  3. Nucleic acids research. 2019, SEP 26; 47(17): 9400-9409.
  1. 16.   Two PKA RIa holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP
  2. Lu, Tsan-Wen; Wu, Jian; Aoto, Phillip C; Weng, Jui-Hung; Ahuja, Lalima G; Sun, Nicholas; Cheng, Cecilia Y; Zhang,Ping; Taylor, Susan S
  3. Proceedings of the National Academy of Sciences of the United States of America. 2019, Aug 13; 116(33): 16347-16356.
  1. 17.   Laboratory mice born to wild mice have natural microbiota and model human immune responses
  2. Rosshart, Stephan P.; Herz, Jasmin; Vassallo, Brian G.; Hunter, Ashli; Wall, Morgan K.; Badger, Jonathan H.; McCulloch, John A.; Anastasakis, Dimitrios G.; Sarshad, Aishe A.; Leonardi, Irina; Collins, Nicholas; Blatter, Joshua A.; Han, Seong-Ji; Tamoutounour, Samira; Potapova, Svetlana; St Claire, Mark B. Foster; Yuan,Wuxing; Sen,Shurjo; Dreier, Matthew S.; Hild, Benedikt; Hafner, Markus; Wang, David; Iliev, Iliyan D.; Belkaid, Yasmine; Trinchieri, Giorgio; Rehermann, Barbara
  3. SCIENCE. 2019, AUG 2; 365(6452): 461-+.
  1. 18.   Allostery in Its Many Disguises: From Theory to Applications
  2. Wodak, Shoshana J.; Paci, Emanuele; Dokholyan, Nikolay; Berezovsky, Igor N.; Horovitz, Amnon; Li, Jing; Hilser, Vincent J.; Behar, Ivet; Karanicolas, John; Stock, Gerhard; Hamm, Peter; Stote, Roland H.; Eberhardt, Jerome; Chebaro, Yassmine; Dejaegere, Annick; Cecchini, Marco; Changeux, Jean-Pierre; Bolhuis, Peter G.; Vreede, Jocelyne; Faccioli, Pietro; Orioli, Simone; Ravasio, Riccardo; Yen, Le; Brito, Carolina; Wyart, Matthieu; Gkeka, Paraskevi; Rivalta, Ivan; Palermo, Giulia; Mccammon, J. Andrew; Panecka-Hofman, Joanna; Wade, Rebecca C.; Di Pizio, Antonella; Niv, Masha Y.; Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum; Padhorny, Dzmitry; Kozakov, Dima; Mcleish, Tom
  3. Structure (London, England : 1993). 2019, Apr 2; 27(4): 566-578.
  1. 19.   Antigen binding allosterically promotes Fc receptor recognition
  2. Zhao, Jun; Nussinov, Ruth; Ma, Buyong
  3. mAbs. 2019, Jan; 11(1): 58-74.
  1. 20.   Development of a Multiplex Glycan Microarray Assay and Comparative Analysis of Human Serum Anti-Glycan IgA, IgG, and IgM Repertoires
  2. Durbin, Sarah V.; Wright, W. Shea; Gildersleeve, Jeffrey
  3. ACS omega. 2018, Dec 31; 3(12): 16882-16891.
  1. 21.   Peptide-MHC (pMHC) binding to a human antiviral T cell receptor induces long-range allosteric communication between pMHC- and CD3-binding sites
  2. Rangarajan, Sneha; He, Yanan; Chen, Yihong; Kerzic, Melissa C.; Ma,Buyong; Gowthaman, Ragul; Pierce, Brian G.; Nussinov,Ruth; Mariuzza, Roy A.; Orban, John
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2018, Oct 12; 293(41): 15991-16005.
  1. 22.   In Silico Methods in Antibody Design
  2. Zhao, Jun; Nussinov, Ruth; Wu, Wen-Jin; Ma, Buyong
  3. ANTIBODIES. 2018, Sep; 7(3):
  1. 23.   Local and global anatomy of antibody-protein antigen recognition
  2. Wang, Meryl; Zhu, David; Zhu, Jianwei; Nussinov, Ruth; Ma, Buyong
  3. Journal of Molecular Recognition: JMR. 2018, May; 31(5): e2693.
  1. 24.   Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2
  2. Ozdemir, E Sila; Jang, Hyunbum; Gursoy, Attila; Keskin, Ozlem; Li, Zhigang; Sacks, David B; Nussinov, Ruth
  3. The Journal of Biological Chemistry. 2018, Mar 9; 293(10): 3685-3699.
  1. 25.   New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model
  2. Konstantinovic, Jelena; Kiris, Erkan; Kota, Krishna P.; Kugelman-Tonos, Johanny; Videnovic, Milica; Cazares, Lisa H.; Jovanovic, Natasa Terzic; Verbic, Tatjana Z.; Andjelkoyic, Boban; Duplantier, Allen J.; Bavari, Sina; Solaja, Bogdan A.
  3. Journal of Medicinal Chemistry. 2018, Feb 22; 61(4): 1595-1608.
NCI at Frederick

You are leaving a government website.

This external link provides additional information that is consistent with the intended purpose of this site. The government cannot attest to the accuracy of a non-federal site.

Linking to a non-federal site does not constitute an endorsement by this institution or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site's privacy policy when you follow the link.

ContinueCancel