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  1. 1.   Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
  2. Feng,Yang; Lee,Jaewon; Yang,Liping; Hilton,Mary; Morris,Karen; Seaman,Steven; Edupuganti,Shivaji; Hsu,Kuo-Sheng; Dower, Christopher; Yu,Guojun; So,Daeho; Bajgain,Pradip; Zhu, Zhongyu; Dimitrov, Dimiter S; Patel,Nimit; Robinson,Christina; Difilippantonio,Simone; Dyba,Marzena; Corbel,Amanda; Basuli, Falguni; Swenson, Rolf E; Kalen,Joseph; Suthe, Sreedhar Reddy; Hussain, Myer; Italia, James S; Souders, Colby A; Gao, Ling; Schnermann,Martin; St Croix,Brad
  3. Cell Reports. 2023, Nov 28; 42(12): 113503.
  1. 2.   Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1ß axes bridge innate immunity and epithelial apoptosis to promote emphysema
  2. Ruwanpura, Saleela M; McLeod, Louise; Dousha, Lovisa F; Seow, Huei J; West, Alison C; West, Alice J; Weng, Teresa; Alanazi, Mohammad; MacDonald, Martin; King, Paul T; Bardin, Philip G; Gabay, Cem; Klinman, Dennis M; Bozinovski, Steven; Vlahos, Ross; Anderson, Gary P; Rose-John, Stefan; Saad, Mohamed I; Jenkins, Brendan J
  3. Proceedings of the National Academy of Sciences of the United States of America. 2022, Sep 06; 119(36): e2201494119.
  1. 3.   Direct anabolic metabolism of three carbon propionate to a six carbon metabolite occurs in vivo across tissues and species
  2. Doan, Mary T; Neinast, Michael D; Varner, Erika L; Bedi, Kenneth; Bartee,David; Jiang, Helen; Trefely, Sophie; Xu, Peining; Singh, Jay P; Jang, Cholsoon; Rame, Eduardo; Brady, Donita; Meier,Jordan; Marguiles, Kenneth; Arany, Zoltan; Snyder, Nathaniel W
  3. Journal of Lipid Research. 2022, May 11; 63(6): 100224.
  1. 4.   An Evolutionarily Conserved AU-Rich Element in the 3' Untranslated Region of a Transcript Misannotated as a Long Noncoding RNA Regulates RNA Stability
  2. Dangelmaier, Emily A; Li, Xiao Ling; Hartford, Corrine Corrina R; King,Julianna; Zibitt, Meira S; Chari,Raj; Grammatikakis, Ioannis; Lal, Ashish
  3. Molecular and cellular biology. 2022, Mar 10; e0050521.
  1. 5.   Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis
  2. Chibaya, Loretah; Karim,Baktiar; Zhang, Hong; Jones,Stephen
  3. Proceedings of the National Academy of Sciences of the United States of America. 2021, Jan 26; 118(4):
  1. 6.   Metabolic but not transcriptional regulation by PKM2 is important for Natural Killer cell responses
  2. Walls,Jessica; Subleski,Jeff; Palmieri,Erika; Gonzalez-Cotto,Marieli; Gardiner, Clair M; McVicar,Daniel; Finlay, David K
  3. eLife. 2020, Aug 19; 9: pii: e59166.
  1. 7.   Structural basis of peptidoglycan endopeptidase regulation
  2. Shin, Jung-Ho; Sulpizio, Alan G; Kelley, Aaron; Alvarez, Laura; Murphy, Shannon G; Fan,Lixin; Cava, Felipe; Mao, Yuxin; Saper, Mark A; Dörr, Tobias
  3. Proceedings of the National Academy of Sciences of the United States of America. 2020, MAY 26; 117(21): 11692-11702.
  1. 8.   Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
  2. Magnussen, Helge M.; Ahmed, Syed F.; Sibbet, Gary J.; Hristova, Ventzislava A.; Nomura, Koji; Hock, Andreas K.; Archibald, Lewis J.; Jamieson, Andrew G.; Fushman, David; Vousden, Karen H.; Weissman, Allan M.; Huang, Danny T.
  3. Nature communications. 2020, Apr 29; 11(1):
  1. 9.   PAM3 supports the generation of M2-like macrophages from lupus patient monocytes and improves disease outcome in murine lupus
  2. Horuluoglu,Begum; Bayik, Defne; Kayraklioglu,Neslihan; Goguet, Emilie; Kaplan, Mariana J.; Klinman,Dennis
  3. Journal of autoimmunity. 2019, MAY; 99: 24-32.
  1. 10.   Immunological monitoring of the tumor immunoenvironment for clinical trials
  2. Malyguine, A. M.; Strobl, S. L.; Shurin, M. R.
  3. Cancer Immunology Immunotherapy. 2012, Feb; 61(2): 239-247.
  1. 11.   DNA intercalator korkormicin A preferentially kills tumor cells expressing wild type p53
  2. Kitagaki, J.; Yang, Y. L.
  3. Biochemical and Biophysical Research Communications. 2011, Oct; 414(1): 186-191.
  1. 12.   Exon array analysis reveals neuroblastoma tumors have distinct alternative splicing patterns according to stage and MYCN amplification status
  2. Guo, X.; Chen, Q. R.; Song, Y. K.; Wei, J. S.; Khan, J.
  3. Bmc Medical Genomics. 2011, Apr; 4: 11.
  1. 13.   Molecular-Level Examination of Cu2+ Binding Structure for Amyloid Fibrils of 40-Residue Alzheimer's beta by Solid-State NMR Spectroscopy
  2. Parthasarathy, S.; Long, F.; Miller, Y.; Xiao, Y. L.; McElheny, D.; Thurber, K.; Ma, B. Y.; Nussinov, R.; Ishii, Y.
  3. Journal of the American Chemical Society. 2011, Mar; 133(10): 3390-3400.
  1. 14.   The p53 Inhibitor MDM2 Facilitates Sonic Hedgehog-Mediated Tumorigenesis and Influences Cerebellar Foliation
  2. Malek, R.; Matta, J.; Taylor, N.; Perry, M. E.; Mendrysa, S. M.
  3. Plos One. 2011, Mar; 6(3): 13.
  1. 15.   Genomic Analyses of Musashi1 Downstream Targets Show a Strong Association with Cancer-related Processes
  2. Abreu, R. D.; Sanchez-Diaz, P. C.; Vogel, C.; Burns, S. C.; Ko, D. J.; Burton, T. L.; Vo, D. T.; Chennasamudaram, S.; Le, S. Y.; Shapiro, B. A.; Penalva, L.
  3. Journal of Biological Chemistry. 2009 284(18): 12125-12135.
  1. 16.   Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation
  2. Feng, H. Q.; Jenkins, L.; Durell, S. R.; Hayashi, R.; Mazur, S. J.; Cherry, S.; Tropea, J. E.; Miller, M.; Wlodawer, A.; Appella, E.; Bai, Y.
  3. Structure. 2009 17(2): 202-210.
  1. 17.   Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III
  2. Hlouchova, K.; Barinka, C.; Konvalinka, J.; Lubkowski, J.
  3. Febs Journal. 2009 276(16): 4448-4462.
  1. 18.   Two Distinct Motifs within the p53 Transactivation Domain Bind to the Taz2 Domain of p300 and Are Differentially Affected by Phosphorylation
  2. Jenkins, L.; Yamaguchi, H.; Hayashi, R.; Cherry, S.; Tropea, J. E.; Miller, M.; Wlodawer, A.; Appella, E.; Mazur, S. J.
  3. Biochemistry. 2009 48(6): 1244-1255.
  1. 19.   Towards inferring time dimensionality in protein-protein interaction networks by integrating structures: the p53 example
  2. Tuncbag, N.; Kar, G.; Gursoy, A.; Keskin, O.; Nussinov, R.
  3. Molecular Biosystems. 2009 5(12): 1770-1778.
  1. 20.   Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53
  2. Clement, J. A.; Kitagaki, J.; Yang, Y.; Saucedo, C. J.; O'Keefe, B. R.; Weissman, A. M.; Mckee, T. C.; McMahon, J. B.
  3. Bioorganic & Medicinal Chemistry. 2008 16(23): 10022-10028.
  1. 21.   Targeting tumor cells expressing p53 with a water-soluble inhibitor of Hdm2
  2. Kitagaki, J.; Agama, K. K.; Pommier, Y.; Yang, Y. L.; Weissman, A. M.
  3. Molecular Cancer Therapeutics. 2008 7(8): 2445-2454.
  1. 22.   Ablation of TNF or lymphotoxin signaling and the frequency of spontaneous tumors in p53-deficient mice
  2. Kuprash, D. V.; Qin, Z. H.; Ito, D.; Grivennikov, S. I.; Abe, K.; Drutskaya, L. N.; Blankenstein, T.; Nedospasov, S. A.
  3. Cancer Letters. 2008 268(1): 70-75.
  1. 23.   Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility
  2. Lee, J. H.; Horak, C. E.; Khanna, C.; Meng, Z. J.; Yu, L. R.; Veenstra, T. D.; Steeg, P. S.
  3. Cancer Research. 2008 68(3): 639-644.
  1. 24.   Experimental validation for quantitative protein network models
  2. Nishizuka, S.; Spurrier, B.
  3. Current Opinion in Biotechnology. 2008 19(1): 41-49.
  1. 25.   Initial sequence and comparative analysis of the cat genome
  2. Pontius, J. U.; Mullikin, J. C.; Smith, D. R.; Lindblad-Toh, K.; Gnerre, S.; Clamp, M.; Chang, J.; Stephens, R.; Neelam, B.; Volfovsky, N.; Schaffer, A. A.; Agarwala, R.; Narfstrom, K.; Murphy, W. J.; Giger, U.; Roca, A. L.; Antunes, A.; Menotti-Raymond, M.; Yuhki, N.; Pecon-Slattery, J.; Johnson, W. E.; Bourque, G.; Tesler, G.; O'Brien, S. J.; NISC Comparative Sequencing Program
  3. Genome Research. 2007, Nov; 17(11): 1675-1689.
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