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  1. 1.   Synthesis, Antitubulin, and Antiproliferative SAR of Analogues of 2-Methoxyestradiol-3,17-O,O-bis-sulfamate
  2. Jourdan, F.; Leese, M. P.; Dohle, W.; Hamel, E.; Ferrandis, E.; Newman, S. P.; Purohit, A.; Reed, M. J.; Potter, B. V. L.
  3. Journal of Medicinal Chemistry. 2010, Apr; 53(7): 2942-2951.
  1. 2.   Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198
  2. LaVallee, T. M.; Burke, P. A.; Swartz, G. M.; Hamel, E.; Agoston, G. E.; Shah, J.; Suwandi, L.; Hanson, A. D.; Fogler, W. E.; Sidor, C. F.; Treston, A. M.
  3. Molecular Cancer Therapeutics. 2008 7(6): 1472-1482.
  1. 3.   Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization
  2. Edsall, A. B.; Mohanakrishnan, A. K.; Yang, D. L.; Fanwick, P. E.; Hamel, E.; Hanson, A. D.; Agoston, G. E.; Cushman, M.
  3. Journal of Medicinal Chemistry. 2004, OCT 7; 47(21): 5126-5139.
  1. 4.   The effect of exchanging various substituents at the 2-position of 2-methoxyestradiol on cytotoxicity in human cancer cell cultures and inhibition of tubulin polymerization
  2. Cushman, M.; Mohanakrishnan, A. K.; Hollingshead, M.; Hamel, E.
  3. Journal of Medicinal Chemistry. 2002 45(21): 4748-4754.
  1. 5.   Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability
  2. Wang, Z. Q.; Yang, D. L.; Mohanakrishnan, A. K.; Fanwick, P. E.; Nampoothiri, P.; Hamel, E.; Cushman, M.
  3. Journal of Medicinal Chemistry. 2000 43(12): 2419-2429.
  1. 6.   A steroid derivative with paclitaxel-like effects on tubulin polymerization
  2. Verdier-Pinard, P.; Wang, Z. Q.; Mohanakrishnan, A. K.; Cushman, M.; Hamel, E.
  3. Molecular Pharmacology. 2000 57(3): 568-575.
  1. 7.   A new anti-tubulin agent containing the benzo
  2. Pinney, K. G.; Bounds, A. D.; Dingeman, K. M.; Mocharla, V. P.; Pettit, G. R.; Bai, R.; Hamel, E.
  3. Bioorganic & Medicinal Chemistry Letters. 1999 9(8): 1081-1086.
  1. 8.   Synthesis of Analogs of 2-Methoxyestradiol With Enhanced Inhibitory Effects On Tubulin Polymerization and Cancer Cell Growth
  2. Cushman, M.; He, H. M.; Katzenellenbogen, J. A.; Varma, R. K.; Hamel, E.; Lin, C. M.; Ram, S.; Sachdeva, Y. P.
  3. Journal of Medicinal Chemistry. 1997 40(15): 2323-2334.
  1. 9.   Cellular Targets of the Anti-Breast Cancer Agent Z-1,1-Dichloro-2,3-Diphenylcyclopropane - Type Ii Estrogen Binding Sites and Tubulin
  2. Terhaar, E.; Hamel, E.; Balachandran, R.; Day, B. W.
  3. Anticancer Research. 1997 17(3C): 1861-1869.
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