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  1. 1.   Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 Dogs
  2. LeBlanc, Amy K.; Mazcko, Christina N.; Cherukuri, Aswini; Berger,Erika; Kisseberth, William C.; Brown, Megan E.; Lana, Susan E.; Weishaar, Kristen; Flesner, Brian K.; Bryan, Jeffrey N.; Vail, David M.; Burton, Jenna H.; Willcox, Jennifer L.; Mutsaers, Anthony J.; Woods, J. Paul; Northrup, Nicole C.; Saba, Corey; Curran, Kaitlin M.; Leeper, Haley; Wilson-Robles, Heather; Wustefeld-Janssens, Brandan G.; Lindley, Stephanie; Smith, Annette N.; Dervisis, Nikolaos; Klahn, Shawna; Higginbotham, Mary Lynn; Wouda, Raelene M.; Krick, Erika; Mahoney, Jennifer A.; London, Cheryl A.; Barber, Lisa G.; Balkman, Cheryl E.; McCleary-Wheeler, Angela L.; Suter, Steven E.; Martin, Olya; Borgatti, Antonella; Burgess, Kristine; Childress, Michael O.; Fidel, Janean L.; Allstadt, Sara D.; Gustafson, Daniel L.; Selmic, Laura E.; Khanna, Chand; Fan, Timothy M.
  3. CLINICAL CANCER RESEARCH. 2021, Jun 1; 27: 3005-3016.
  1. 2.   MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells
  2. Viola, G.; Bortolozzi, R.; Hamel, E.; Moro, S.; Brun, P.; Castagliuolo, I.; Ferlin, M. G.; Basso, G.
  3. Biochemical Pharmacology. 2012, Jan; 83(1): 16-26.
  1. 3.   mTOR Kinase Inhibitor AZD8055 Enhances the Immunotherapeutic Activity of an Agonist CD40 Antibody in Cancer Treatment
  2. Jiang, Q.; Weiss, J. M.; Back, T.; Chan, T.; Ortaldo, J. R.; Guichard, S.; Wiltrout, R. H.
  3. Cancer Research. 2011, Jun; 71(12): 4074-4084.
  1. 4.   Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential anti-astrocytoma therapies
  2. Gursel, D. B.; Connell-Albert, Y. S.; Tuskan, R. G.; Anastassiadis, T.; Walrath, J. C.; Hawes, J. J.; Amlin-Van Schaick, J. C.; Reilly, K. M.
  3. Neuro-Oncology. 2011, Jun; 13(6): 610-621.
  1. 5.   Rapamycin Protects Mice from Staphylococcal Enterotoxin B-Induced Toxic Shock and Blocks Cytokine Release In Vitro and In Vivo
  2. Krakauer, T.; Buckley, M.; Issaq, H. J.; Fox, S. D.
  3. Antimicrobial Agents and Chemotherapy. 2010, Mar; 54(3): 1125-1131.
  1. 6.   The Neurofibromatosis Type 1 Tumor Suppressor Controls Cell Growth by Regulating Signal Transducer and Activator of Transcription-3 Activity In vitro and In vivo
  2. Banerjee, S.; Byrd, J. N.; Gianino, S. M.; Harpstrite, S. E.; Rodriguez, F. J.; Tuskan, R. G.; Reilly, K. M.; Piwnica-Worms, D. R.; Gutmann, D. H.
  3. Cancer Research. 2010, Feb; 70(4): 1356-1366.
  1. 7.   Resistance to IFN-alpha-Induced Apoptosis Is Linked to a Loss of STAT2
  2. Romero-Weaver, A. L.; Wang, H. W.; Steen, H. C.; Scarzello, A. J.; Hall, V. L.; Sheikh, F.; Donnelly, R. P.; Gamero, A. M.
  3. Molecular Cancer Research. 2010, Jan; 8(1): 80-92.
  1. 8.   Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors
  2. Granville, C. A.; Warfel, N.; Tsurutani, J.; Hollander, M. C.; Robertson, M.; Fox, S. D.; Veenstra, T. D.; Issaq, H. J.; Linnoila, R. I.; Dennis, P. A.
  3. Clinical Cancer Research. 2007, Apr; 13(7): 2281-2289.
  1. 9.   Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma
  2. Rudelius, M.; Pittaluga, S.; Nishizuka, S.; Pham, T. H. T.; Fend, F.; Jaffe, E. S.; Quintanilla-Martinez, L.; Raffeld, M.
  3. Blood. 2006, Sep; 108(5): 1668-1676.
  1. 10.   Inhibiting hypoxia-inducible factor 1 for cancer therapy
  2. Melillo, G.
  3. Molecular Cancer Research. 2006, Sep; 4(9): 601-605.
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