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  1. 1.   Polymerase theta inhibitors combinations with approved and investigational agents in patient-derived tumor multi-cell type (mct) spheroids
  2. Teicher, Beverly A; Dexheimer,Thomas; Chen,Li; Silvers, Thomas; Jones,Eric; Coussens,Nathan; Eder, J Paul; Doroshow, James H
  3. Experimental and Molecular Pathology. 2025, Jun 27; 143: 104978.
  1. 2.   Unraveling the mechanism of RNA duplex unwinding by DEAD-box helicase DDX3X: Insights into Cooperativity and roles of protomers
  2. Dharavath, Sudhaker; Song, He; Ji, Xinhua
  3. Biochemical and Biophysical Research Communications. 2025, Jun 13; 777: 152206.
  1. 3.   Benzosuberene and Tetracyclic Analogues as Colchicine Site Inhibitors of Tubulin Polymerization
  2. VanNatta, Jennifer M; Carlson, Graham J; Niu, Haichan; Bai, Ruoli; Wanniarachchi, Hashini I; Schuetze, Regan; Trawick, Mary Lynn; Hamel,Ernest; Mason, Ralph P; Pinney, Kevin G
  3. ACS Medicinal Chemistry Letters. 2025, Jun 12; 16(6): 1098-1107.
  1. 4.   Phase 1 studies of the indenoisoquinolines LMP776 and LMP744 in patients with solid tumors and lymphomas
  2. O'Sullivan Coyne, Geraldine; Kummar, Shivaani; Rubinstein, Larry V; Wilsker,Deborah; Moore, Nancy; Hogu, Murielle; Piekarz, Richard; Covey, Joe; Beumer, Jan H; Ferry-Galow,Katherine; Villaruz, Liza C; Hollingshead,Melinda; Holleran, Julianne L; Deppas, Joshua J; Pommier, Yves; Ko, Brian; Johnson, Barry C; Parchhment, Ralph E; Ivy, Percy; Doroshow, James H; Chen, Alice P
  3. Cancer Chemotherapy and Pharmacology. 2025, May 29; 95(1): 58.
  1. 5.   Development of a workflow for in vitro on- and off-target cytotoxicity assessment of CAR T cell therapies to support first-in-human clinical trials: An orthogonal approach using human induced pluripotent stem cell-derived cells as a surrogate for normal vital organ systems
  2. Price,Shari; Zindel,Krista; Overcash,Justin; Glaze, Elizabeth; Eldridge, Sandy
  3. Current Research in Toxicology. 2025, May 28; 8: 100243.
  1. 6.   Changes in Generations of PAMAM Dendrimers and Compositions of Nucleic Acid Nanoparticles Govern Delivery and Immune Recognition
  2. Avila, Yelixza I; Rebolledo, Laura P; Leal Santos, Nathalia; Rawlins, Brandon; Radwan, Yasmine; Andrade-Muñoz, Melanie; Skelly, Elizabeth; Chandler, Morgan R; Andrade, Luciana N S; Kim, Tae Jin; Dobrovolskaia,Marina; Afonin, Kirill A
  3. ACS Biomaterials Science & Engineering. 2025, May 20;
  1. 7.   Harnessing molecular recognition for small molecule-mediated, reversible photochemical control over mRNA translation
  2. Parmar,Shaifaly; Tenney, Logan; Liang, Xiao; Routzahn,John; Sibley, Christopher D; Schneekloth,John
  3. Angewandte Chemie (International ed. in English). 2025, Mar 31; e202503078.
  1. 8.   Donor telomeres and their magnitude of shortening post-allogeneic haematopoietic cell transplant impact survival for patients with early-stage leukaemia or myelodysplastic syndrome
  2. Gadalla, Shahinaz M; Katki, Hormuzd A; Lai, Tsung-Po; Auer, Paul L; Dagnall,Casey; Bupp, Caitrin; Hutchinson, Amy A; Anderson, James J; Mendez, Kyra J W; Spellman, Stephen R; Stewart, Valerie; Savage, Sharon A; Lee, Stephanie J; Levine, John E; Saber, Wael; Aviv, Abraham
  3. EBioMedicine. 2025, Mar 08; 114: 105641.
  1. 9.   Occupational Pesticide Use and Relative Leukocyte Telomere Length in the Biomarkers of Exposure and Effect in Agriculture Study
  2. Erickson, Patricia A; Chang, Vicky C; He, Shisi; Dagnall,Casey; Teshome,Kedest; Machiela, Mitchell J; Barry, Kathryn Hughes; Pereira, Edna F R; Gadalla, Shahinaz M; Parks, Christine G; Berndt, Sonja I; Beane Freeman, Laura E; Andreotti, Gabriella; Hofmann, Jonathan N
  3. Environmental Research. 2025, Feb 20; 273: 121174.
  1. 10.   Olaparib in treatment-refractory isocitrate dehydrogenase 1 (IDH1)- and IDH2-mutant cholangiocarcinoma: Safety and antitumor activity from the phase 2 National Cancer Institute 10129 trial
  2. Cecchini, Michael; Pilat, Mary Jo; Uboha, Nataliya; Azad, Nilofer S; Cho, May; Davis, Elizabeth J; Ahnert, Jordi Rodon; Tinoco, Gabriel; Shapiro, Geoffrey I; Khagi, Simon; Powers, Benjamin; Spencer, Kristen; Groisberg, Roman; Drappatz, Jan; Chen, Li; Das,Bishu; Bao, Xun; Li, Jing; Narayan, Azeet; Vu, Dennis; Patel, Abhijit; Niger, Monica; Doroshow, Deborah; Durecki, Diane; Boerner, Scott A; Bindra, Ranjit; Ivy, Percy; Shyr, Derek; Shyr, Yu; LoRusso, Patricia M
  3. Cancer. 2025, Feb 15; 131(4): e35755.
  1. 11.   Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered through Cleavable and Non-Cleavable Linkers
  2. Ford, Jacob W; VanNatta, Jennifer M; Mondal, Deboprosad; Lin, Chen-Ming; Deng, Yuling; Bai, Ruoli; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G
  3. Tetrahedron. 2025, Feb 01; 171
  1. 12.   Design, Synthesis and Biological Evaluation of 2-Phenyl Indole Analogues of OXi8006 as Colchicine Site Inhibitors of Tubulin Polymerization and Vascular Disrupting Agents
  2. Vairin, Rebecca; Tamminga, Caleb; Shi, Zhe; Borchardt, Christian; Jambulapati, Jayaram; Bai, Ruoli; Wanniarachchi, Hashini; Bueno, Lorena; Hamel,Ernest; Mason, Ralph P; Trawick, Mary Lynn; Pinney, Kevin G
  3. Bioorganic & Medicinal Chemistry. 2024, Nov 07; 118: 117981.
  1. 13.   Two hearts beat as one: the debate over RAS dimers continues
  2. Stephen,Andy
  3. Trends in Biochemical Sciences. 2024, Nov; 49(11): 933-935.
  1. 14.   Telomere length and clonal chromosomal alterations in peripheral blood of patients with severe aplastic anaemia
  2. Strauss, Joshua D; Brown, Derek W; Zhou, Weiyin; Dagnall,Casey; Yuan, Jian-Min; Im, Annie; Savage, Sharon A; Wang, Youjin; Rafati, Maryam; Spellman, Stephen R; Gadalla, Shahinaz M
  3. British Journal of Haematology. 2024, Aug 05;
  1. 15.   Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation
  2. Zhang, Peng; Gorman, Jason; Tsybovsky,Yaroslav; Lu, Maolin; Liu, Qingbo; Gopan, Vinay; Singh, Mamta; Lin, Yin; Miao, Huiyi; Seo, Yuna; Kwon, Alice; Olia, Adam S; Chuang, Gwo-Yu; Geng, Hui; Lai, Yen-Ting; Zhou, Tongqing; Mascola, John R; Mothes, Walther; Kwong, Peter D; Lusso, Paolo
  3. Cell Reports. 2024, Jul 18; 43(8): 114518.
  1. 16.   Association between telomere length and Plasmodium falciparum malaria endemicity in sub-Saharan Africans
  2. McQuillan, Michael A; Verhulst, Simon; Hansen, Matthew E B; Beggs, William; Meskel, Dawit Wolde; Belay, Gurja; Nyambo, Thomas; Mpoloka, Sununguko Wata; Mokone, Gaonyadiwe George; Fokunang, Charles; Njamnshi, Alfred K; Chanock, Stephen J; Aviv, Abraham; Tishkoff, Sarah A
  3. American Journal of Human Genetics. 2024, May 02; 111(5): 927-938.
  1. 17.   Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer's disease
  2. Qiu, Yunguang; Hou, Yuan; Gohel, Dhruv; Zhou, Yadi; Xu, Jielin; Bykova, Marina; Yang, Yuxin; Leverenz, James B; Pieper, Andrew A; Nussinov,Ruth; Caldwell, Jessica Z K; Brown, J Mark; Cheng, Feixiong
  3. Cell Reports. 2024, Apr 21; 43(5): 114128.
  1. 18.   Germline pathogenic variants associated with triple-negative breast cancer in US Hispanic and Guatemalan women using hospital and community-based recruitment strategies
  2. Godinez Paredes, Jesica M; Rodriguez, Isabel; Ren, Megan; Orozco, Anali; Ortiz, Jeremy; Albanez, Anaseidy; Jones, Catherine; Nahleh, Zeina; Barreda, Lilian; Garland,Lisa; Torres-Gonzalez, Edmundo; Wu,Dongjing; Luo,Wen; Liu,Jia; Argueta, Victor; Orozco, Roberto; Gharzouzi, Eduardo; Dean, Michael
  3. Breast Cancer Research and Treatment. 2024, Mar 23;
  1. 19.   Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response
  2. Lee, Unsun; Szabova,Ludmila; Collins, Victor J; Gordon, Melanie; Johnson,Kristine; Householder, Deborah; Jorgensen,Stephanie; Lu, Lucy; Bassel,Laura; Elloumi, Fathi; Peer, Cody J; Nelson, Ariana E; Varriano, Sophia; Varma, Sudhir; Roberts, Ryan D; Ohler,Zoe; Figg, William D; Sharan, Shyam K; Pommier, Yves; Heske, Christine M
  3. Frontiers in Cell and Developmental Biology. 2024 12: 1462840.
  1. 20.   Purification of Circular RNAs Using Poly(A) Tailing Followed by RNase R Digestion
  2. Xiao, Mei-Sheng; Wilusz, Jeremy E
  3. Methods in Molecular Biology (Clifton, N.J.). 2024 2765: 3-19.
  1. 21.   Quantitation of Active Pharmaceutical Ingredients in Polymeric Drug Products Using Elemental Analysis
  2. Xu,Jie; Hu, Yingwen; Clogston,Jeffrey
  3. Methods in Molecular Biology (Clifton, N.J.). 2024 2789: 35-43.
  1. 22.   Development of a bicistronic anti-CD19/CD20 CAR construct including abrogation of unexpected nucleic acid sequence deletions
  2. Lam, Norris; Finney, Richard; Yang, Shicheng; Choi, Stephanie; Wu,Xiaolin; Cutmore, Lauren; Andrade, Jorge; Huang, Lei; Amatya, Christina; Cam, Margaret; Kochenderfer, James N
  3. Molecular Therapy Oncolytics. 2023, Sep 21; 30: 132-149.
  1. 23.   Synthesis and biological evaluation of structurally diverse 6-aryl-3-aroyl-indole analogues as inhibitors of tubulin polymerization
  2. Ren, Wen; Deng, Yuling; Ward, Jacob D; Vairin, Rebecca; Bai,Ruoli; Wanniarachchi, Hashini I; Hamal, Khagendra B; Tankoano, Pouguiniseli E; Tamminga, Caleb S; Bueno, Lorena M A; Hamel,Ernest; Mason, Ralph P; Trawick, Mary Lynn; Pinney, Kevin G
  3. European Journal of Medicinal Chemistry. 2023, Sep 06; 263: 115794.
  1. 24.   An Investigation of Structure-Activity Relationships and Cell Death Mechanisms of the Marine Alkaloids Discorhabdins in Merkel Cell Carcinoma Cells
  2. Orfanoudaki,Maria; Smith,Emily; Hill, Natasha T; Garman, Khalid A; Brownell, Isaac; Copp, Brent R; Grkovic,Tanja; Henrich,Curtis
  3. Marine Drugs. 2023, Aug 29; 21(9):
  1. 25.   Novel Indole-Pyrazole Hybrids as Potential Tubulin-Targeting Agents; Synthesis, antiproliferative evaluation, and molecular modeling studies
  2. Hawash, Mohammed; Ergun, Sezen Guntekin; Kahraman, Deniz Cansen; Olgac, Abdurrahman; Hamel,Ernest; Cetin-Atalay, Rengul; Baytas, Sultan Nacak
  3. Journal of Molecular Structure. 2023, Aug 05; 1285
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