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  1. 1.   Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
  2. Magnussen, Helge M.; Ahmed, Syed F.; Sibbet, Gary J.; Hristova, Ventzislava A.; Nomura, Koji; Hock, Andreas K.; Archibald, Lewis J.; Jamieson, Andrew G.; Fushman, David; Vousden, Karen H.; Weissman, Allan M.; Huang, Danny T.
  3. Nature communications. 2020, Apr 29; 11(1):
  1. 2.   The p53 Inhibitor MDM2 Facilitates Sonic Hedgehog-Mediated Tumorigenesis and Influences Cerebellar Foliation
  2. Malek, R.; Matta, J.; Taylor, N.; Perry, M. E.; Mendrysa, S. M.
  3. Plos One. 2011, Mar; 6(3): 13.
  1. 3.   Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53
  2. Clement, J. A.; Kitagaki, J.; Yang, Y.; Saucedo, C. J.; O'Keefe, B. R.; Weissman, A. M.; Mckee, T. C.; McMahon, J. B.
  3. Bioorganic & Medicinal Chemistry. 2008 16(23): 10022-10028.
  1. 4.   Targeting tumor cells expressing p53 with a water-soluble inhibitor of Hdm2
  2. Kitagaki, J.; Agama, K. K.; Pommier, Y.; Yang, Y. L.; Weissman, A. M.
  3. Molecular Cancer Therapeutics. 2008 7(8): 2445-2454.
  1. 5.   Tumor suppression and normal aging in mice with constitutively high p53 activity
  2. Mendrysa, S. M.; O'Leary, K. A.; McElwee, M. K.; Michalowski, J.; Eisenman, R. N.; Powell, D. A.; Perry, M. E.
  3. Genes & Development. 2006, JAN 1; 20(1): 16-21.
  1. 6.   Regulating the p53 system through ubiquitination
  2. Yang, Y. L.; Li, C. C. H.; Weissman, A. M.
  3. Oncogene. 2004 23(11): 2096-2106.
  1. 7.   Stress signals utilize multiple pathways to stabilize p53
  2. Ashcroft, M.; Taya, Y.; Vousden, K. H.
  3. Molecular and Cellular Biology. 2000 20(9): 3224-3233.
  1. 8.   Regulation and activation of p53 and its family members
  2. Lohrum, M. A. E.; Vousden, K. H.
  3. Cell Death and Differentiation. 1999 6(12): 1162-1168.
  1. 9.   Regulation of p53 stability
  2. Ashcroft, M.; Vousden, K. H.
  3. Oncogene. 1999 18(53): 7637-7643.
  1. 10.   Regulation of Mdm2-Directed Degradation By the C Terminus of P53
  2. Kubbutat, M. H. G.; Ludwig, R. L.; Ashcroft, M.; Vousden, K. H.
  3. Molecular and Cellular Biology. 1998 18(10): 5690-5698.
  1. 11.   Regulation of P53 Stability By Mdm2
  2. Kubbutat, M. H. G.; Jones, S. N.; Vousden, K. H.
  3. Nature. 1997 387(6630): 299-303.
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