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  1. 1.   The structural basis of BCR-ABL recruitment of GRB2 in chronic myelogenous leukemia
  2. Liu,Yonglan; Jang,Hyunbum; Zhang,Mingzhen; Tsai,Chung-Jung; Maloney,Ryan; Nussinov,Ruth
  3. Biophysical Journal. 2022, May 31;
  1. 3.   Isothiazolidinone (IZD) as a phosphoryl mimetic in inhibitors of the Yersinia pestis protein tyrosine phosphatase YopH
  2. Kim, S. E.; Bahta, M.; Lountos, G. T.; Ulrich, R. G.; Burke, T. R.; Waugh, D. S.
  3. Acta Crystallographica Section D-Biological Crystallography. 2011, Jul; 67: 639-645.
  1. 5.   Structure-based design of potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics
  2. Jiang, S.; Li, P.; Peach, M. L.; Bindu, L.; Worthy, K. W.; Fisher, R. J.; Burke, T. R.; Nicklaus, M.; Roller, P. P.
  3. Biochemical and Biophysical Research Communications. 2006, Oct; 349(2): 497-503.
  1. 6.   Application of azide-alkyne cycloaddition 'click chemistry' for the synthesis of Grb2 SH2 domain-binding macrocycles
  2. Choi, W. J.; Shi, Z. D.; Worthy, K. M.; Bindu, L.; Karki, R. G.; Nicklaus, M. C.; Fisher, R. J.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry Letters. 2006, Oct; 16(20): 5265-5269.
  1. 7.   Oncogenic met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling
  2. Mood, K.; Saucier, C.; Ishimura, A.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Journal of Cellular Physiology. 2006, APR; 207(1): 271-285.
  1. 8.   Design and synthesis of phosphonodifluoromethyl phenylalanine (F(2)Pmp): A useful phosphotyrosyl mimetic
  2. Burke, T. R.
  3. Current Topics in Medicinal Chemistry. 2006 6(14): 1465-1471.
  1. 9.   Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain
  2. Phan, J.; Shi, Z. D.; Burke, T. R.; Waugh, D. S.
  3. Journal of Molecular Biology. 2005, OCT 14; 353(1): 104-115.
  1. 10.   Synthesis of alpha,alpha-disubstituted 4-phosphonophenylalanine analogues as conformationally-constrained phosphotyrosyl mimetics
  2. Oishi, S.; Kang, S. U.; Liu, H. P.; Zhang, M. C.; Yang, D. J.; Deschamps, J. R.; Burke, T. R.
  3. Tetrahedron. 2004 60(13): 2971-2977.
  1. 11.   Development of L-3-aminotyrosine suitably protected for the synthesis of a novel nonphosphorylated hexapeptide with low-nanomolar Grb2-SH2 domain-binding affinity
  2. Song, Y. L.; Roller, P. P.; Long, Y. Q.
  3. Bioorganic & Medicinal Chemistry Letters. 2004 14(12): 3205-3208.
  1. 12.   Synthesis of the first alpha-fluoro-phosphotyrosyl mimetic
  2. Shi, Z. D.; Liu, H. P.; Zhang, M. C.; Yang, D. J.; Burke, T. R.
  3. Synthetic Communications. 2004 34(21): 3883-3889.
  1. 13.   Structural basis for a non-phosphorus-containing cyclic peptide binding to Grb2-SH2 domain with high affinity
  2. Li, P.; Zhang, M. C.; Peach, M. L.; Zhang, X. D.; Liu, H. P.; Nicklaus, M.; Yang, D. J.; Roller, P. P.
  3. Biochemical and Biophysical Research Communications. 2003 307(4): 1038-1044.
  1. 14.   Global optimization of conformational constraint on non- phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain
  2. Long, Y. Q.; Lung, F. D. T.; Roller, P. P.
  3. Bioorganic & Medicinal Chemistry. 2003 11(18): 3929-3936.
  1. 15.   Structure-based design of thioether-bridged cyclic phosphopeptides binding to Grb2-SH2 domain
  2. Li, P.; Peach, M. L.; Zhang, M. C.; Liu, H. P.; Yang, D. J.; Nicklaus, M.; Roller, P. P.
  3. Bioorganic & Medicinal Chemistry Letters. 2003 13(5): 895-899.
  1. 16.   Concise and enantioselective synthesis of Fmoc-Pmp(BUt)(2)-OH and design of potent Pmp-containing Grb2-SH2 domain antagonists
  2. Li, P.; Zhang, M. C.; Peach, M. L.; Liu, H. P.; Yang, D. J.; Roller, P. P.
  3. Organic Letters. 2003 5(17): 3095-3098.
  1. 17.   Tripeptide inhibitors of Yersinia protein-tyrosine phosphatase
  2. Lee, K.; Gao, Y.; Yao, Z. J.; Phan, J.; Wu, L.; Liang, J.; Waugh, D. S.; Zhang, Z. Y.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry Letters. 2003 13(15): 2577-2581.
  1. 18.   Phosphotyrosyl mimetics in the development of signal transduction inhibitors
  2. Burke, T. R.; Lee, K.
  3. Accounts of Chemical Research. 2003 36(6): 426-433.
  1. 19.   Design and synthesis of a beta-amino phosphotyrosyl mimetic suitably protected for peptide synthesis
  2. Lee, K.; Zhang, M. C.; Yang, D. J.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry Letters. 2002 12(23): 3399-3401.
  1. 20.   Low-molecular-weight protein tyrosine phosphatase is a positive component of the fibroblast growth factor receptor signaling pathway
  2. Park, E. K.; Warner, N.; Mood, K.; Pawson, T.; Daar, I. O.
  3. Molecular and Cellular Biology. 2002 22(10): 3404-3414.
  1. 21.   Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: Specific association of p68-Sck/ShcB with pp135
  2. Kojima, T.; Yoshikawa, Y.; Takada, S.; Sato, M.; Nakamura, T.; Takahashi, N.; Copeland, N. G.; Gilbert, D. J.; Jenkins, N. A.; Mori, N.
  3. Biochemical and Biophysical Research Communications. 2001 284(4): 1039-1047.
  1. 22.   N-terminal carboxyl and tetrazole-containing amides as adjuvants to Grb2 SH2 domain ligand binding
  2. Burke, T. R.; Yao, Z. J.; Gao, Y.; Wu, J. X.; Zhu, X. F.; Luo, J. H.; Guo, R. B.; Yang, D. J.
  3. Bioorganic & Medicinal Chemistry. 2001 9(6): 1439-1445.
  1. 23.   Cloning protein tyrosine kinases by screening cDNA libraries with antiphosphotyrosine antibodies
  2. Chong, L. D.; Daar, I. O.
  3. Methods in molecular biology (Clifton, N.J.). 2001 124: 21-37.
  1. 24.   Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene
  2. Fantin, V. R.; Lavan, B. E.; Wang, Q.; Jenkins, N. A.; Gilbert, D. J.; Copeland, N. G.; Keller, S. R.; Lienhard, G. E.
  3. Endocrinology. 1999 140(3): 1329-1337.
  1. 25.   Induction of TNF alpha in macrophages by vanadate is dependent on activation of transcription factor NF-kappa B and free radical reactions
  2. Ye, J. P.; Ding, M.; Zhang, X. Y.; Rojanasakul, Y.; Nedospasov, S.; Vallyathan, V.; Castronova, V.; Shi, X. L.
  3. Molecular and Cellular Biochemistry. 1999 198(1-2): 193-200.
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