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  1. 1.   Association between prediagnostic serum metabolites and pancreatic ductal adenocarcinoma risk in two prospective cohorts
  2. Zhang, Ting; Moore, Steven C; Fu, Sheng; Wang,Xiaoyu; Albanes, Demetrius; Weinstein, Stephanie J; Yu, Kai; Stolzenberg-Solomon, Rachael Z
  3. International Journal of Cancer. 2025, May 22;
  1. 2.   The Janus kinase 1 is critical for pancreatic cancer initiation and progression
  2. Shrestha, Hridaya; Rädler, Patrick D; Dennaoui, Rayane; Wicker, Madison N; Rajbhandari, Nirakar; Sun, Yunguang; Peck, Amy R; Vistisen, Kerry; Triplett, Aleata A; Beydoun, Rafic; Sterneck,Esta; Saur, Dieter; Rui, Hallgeir; Wagner, Kay-Uwe
  3. Cell Reports. 2024, May 10; 43(5): 114202.
  1. 3.   Tumor resistance to anti-mesothelin CAR-T cells caused by binding to shed mesothelin is overcome by targeting a juxtamembrane epitope
  2. Liu, X F; Onda, M; Schlomer,Jerome; Bassel,Laura; Kozlov,Serguei; Tai, C-H; Zhou, Q; Liu, W; Tsao, H-E; Hassan, R; Ho, M; Pastan, I
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Jan 23; 121(4): e2317283121.
  1. 4.   Target-Specific Nanoparticle Polyplex Down-Regulates Mutant Kras to Prevent Pancreatic Carcinogenesis and Halt Tumor Progression
  2. Smith, Jill P; Chen, Wenqiang; Shivapurkar, Narayan; Gerber, Monica; Tucker, Robin D; Kallakury, Bhaskar; Dasa, Siva Sai Krishna; Kularatne,Ruvanthi Nilanga; Stern,Steve
  3. International Journal of Molecular Sciences. 2023, Jan 01; 24(1):
  1. 5.   Novel Regulators of Macropinocytosis-Dependent Growth Revealed by Informer Set Library Screening in Pancreatic Cancer Cells
  2. Kim, Sang Hoon; Song, Jae Ho; Kim, Min Ji; Song, Mun Gu; Ku, Angel A; Bandyopadhyay, Sourav; McCormick, Frank; Kim, Sung Eun
  3. Metabolites. 2022, Sep 02; 12(9):
  1. 6.   Cholecystokinin-B Receptor-Targeted Nanoparticle for Imaging and Detection of Precancerous Lesions in the Pancreas
  2. Smith, Jill P.; Cao, Hong; Edmondson,Elijah; Dasa,Siva Sai Krishna; Stern,Steve
  3. BIOMOLECULES. 2021, Dec; 11(12):
  1. 7.   Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model
  2. Yamamoto, Jun; Miyake, Kentaro; Han, Qinghong; Tan, Yuying; Inubushi, Sachiko; Sugisawa, Norihiko; Higuchi, Takashi; Tashiro, Yoshihiko; Nishino, Hiroto; Homma, Yuki; Matsuyama, Ryusei; Chawla, Sant P; Bouvet, Michael; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Cancer letters. 2020, NOV 1; 492: 174-184.
  1. 8.   Novel targets identified by integrated cancer-stromal interactome analysis of pancreatic adenocarcinoma
  2. Hiroshima, Yukihiko; Kasajima, Rika; Kimura, Yayoi; Komura, Daisuke; Ishikawa, Shumpei; Ichikawa, Yasushi; Bouvet, Michael; Yamamoto, Naoto; Oshima, Takashi; Morinaga, Soichiro; Singh,Shree Ram; Hoffman, Robert M; Endo, Itaru; Miyagi, Yohei
  3. Cancer letters. 2020, Jan 28; 469: 217-227.
  1. 9.   Oral microbial community composition is associated with pancreatic cancer: A case-control study in Iran
  2. Vogtmann, Emily; Han, Yongli; Caporaso, J Gregory; Bokulich, Nicholas; Mohamadkhani, Ashraf; Moayyedkazemi, Alireza; Hua, Xing; Kamangar, Farin; Wan, Yunhu; Suman, Shalabh; Zhu,Bin; Hutchinson,Amy; Dagnall,Casey; Jones,Kristine; Hicks,Belynda; Shi, Jianxin; Malekzadeh, Reza; Abnet, Christian C; Pourshams, Akram
  3. Cancer medicine. 2019, Nov 21;
  1. 10.   Induction of Metastasis by Low-dose Gemcitabine in a Pancreatic Cancer Orthotopic Mouse Model: An Opposite Effect of Chemotherapy
  2. Sugisawa, Norihiko; Miyake, Kentaro; Higuchi, Takashi; Oshiro, Hiromichi; Zhang, Zhiying; Park, Jun Ho; Kawaguchi, Kei; Chawla, Sant P; Bouvet, Michael; Singh,Shree Ram; Unno, Michiaki; Hoffman, Robert M
  3. Anticancer research. 2019, Oct; 39(10): 5339-5344.
  1. 11.   A pharmacogenomic analysis using L1000CDS2 identifies BX-795 as a potential anticancer drug for primary pancreatic ductal adenocarcinoma cells
  2. Choi, Eun A; Choi, Yeon Sook; Lee, Eun Ji; Singh,Shree Ram; Kim, Song Cheol; Chang, Suhwan
  3. Cancer letters. 2019, Aug 09; 465: 82-93.
  1. 12.   Role of nitric oxide in pancreatic cancer cells exhibiting the invasive phenotype
  2. Fujita, Mayumi; Somasundaram,Veena; Basudhar,Debashree; Cheng,Robert; Ridnour,Lisa; Higuchi, Harumi; Imadome, Kaori; No, Jae Hong; Bharadwaj, Gaurav; Wink,David
  3. REDOX BIOLOGY. 2019, Apr; 22
  1. 13.   Protein Synthesis Inhibition Activity of Mesothelin Targeting Immunotoxin LMB-100 Decreases Concentrations of Oncogenic Signaling Molecules and Secreted Growth Factors
  2. El-Behaedi, Salma; Landsman, Rebekah; Rudloff, Michael; Kolyvas, Emily; Albalawy, Rakan; Zhang, Xianyu; Bera, Tapan; Collins, Keith; Kozlov, Serguei; Alewine, Christine
  3. Toxins. 2018, Nov; 10(11): pii: E447.
  1. 14.   Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer
  2. Kawaguchi, Kei; Miyake, Kentaro; Han, Qinghong; Li, Shukuan; Tan, Yuying; Igarashi, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Higuchi, Takashi; Oshiro, Hiromichi; Zhang, Zhiying; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Bouvet, Michael; Singh, Shree Ram; Unno, Michiaki; Hoffman, Robert M
  3. Cancer Letters. 2018, Jun 18; 432: 251-259.
  1. 15.   MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Lwin, Thinzar M; Miyake, Masuyo; Kiyuna, Tasuku; Hwang, Ho Kyoung; Murakami, Takashi; Delong, Jonathan C; Singh, Shree Ram; Clary, Bryan; Bouvet, Michael; Unno, Michiaki; Hoffman, Robert M
  3. Tissue & cell. 2018, Jun; 52: 124-128.
  1. 16.   Intrinsic protein disorder in oncogenic KRAS signaling
  2. Nussinov, Ruth; Jang, Hyunbum; Tsai, Chung-Jung; Liao, Tsung-Jen; Li, Shuai; Fushman, David; Zhang, Jian
  3. Cellular and Molecular Life Sciences . 2017, Sep; 74(17): 3245-3261.
  1. 17.   Dual Oxidase2 and pancreatic adenocarcinoma: IFN-gamma-mediated dual oxidase2 overexpression results in H2O2-induced, ERKassociated up-regulation of HIF-1alpha and VEGF-A
  2. Wu, Y.; Meitzler, J. L.; Antony, S.; Juhasz, A.; Lu, J.; Jiang, G.; Liu, H.; Hollingshead, M.; Haines, D. C.; Butcher, D.; Panter, M. S.; Roy, K.; Doroshow, J. H.
  3. Oncotarget. 2016, 15-Sep; 7(42): 68412-68433.
  1. 18.   Lack of germline PALB2 mutations in melanoma-prone families with CDKN2A mutations and pancreatic cancer
  2. Yang, X. H. R.; Jessop, L.; Myers, T.; Amundadottir, L.; Pfeiffer, R. M.; Wheeler, W.; Pike, K. M.; Yuenger, J.; Burdett, L.; Yeager, M.; Chanock, S. J.; Tucker, M. A.; Goldstein, A. M.
  3. Familial Cancer. 2011, Sep; 10(3): 545-548.
  1. 19.   Increased Expression of DNA Repair Genes in Invasive Human Pancreatic Cancer Cells
  2. Mathews, L. A.; Cabarcas, S. M.; Hurt, E. M.; Zhang, X. H.; Jaffee, E. M.; Farrar, W. L.
  3. Pancreas. 2011, Jul; 40(5): 730-739.
  1. 20.   The Role of Stromal Components in Pancreatic Cancer Progression
  2. Xu, Mengdan; Zhou, Binhua P.; Tao, Min; Liu, Jingyi; Li, Wei
  3. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. 2016 16(9): 1117-1124.
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