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  1. 1.   Fine-tuning probes for fluorescence polarization binding assays of bivalent ligands against polo-like kinase 1 using full-length protein
  2. Tsuji, Kohei; Tamamura, Hirokazu; Burke,Terrence
  3. Bioorganic & Medicinal Chemistry . 2024, Dec 28; 119: 118055.
  1. 2.   Specific inhibition of an anticancer target, polo-like kinase 1, by allosterically dismantling its mechanism of substrate recognition
  2. Park, Jung-Eun; Kirsch, Klara; Lee, Hobin; Oliva, Paola; Ahn, Jong Il; Ravishankar, Harsha; Zeng, Yan; Fox,Stephen; Kirby, Samuel A; Badhwar, Pooja; Andresson,Thorkell; Jacobson, Kenneth A; Lee, Kyung S
  3. Proceedings of the National Academy of Sciences of the United States of America. 2023, Aug 29; 120(35): e2305037120.
  1. 3.   Autophosphorylation-induced self-assembly and STIL-dependent reinforcement underlie Plk4's ring-to-dot localization conversion around a human centriole
  2. Park, Jung-Eun; Meng, Lingjun; Ryu, Eun Kyoung; Nagashima,Kunio; Baxa,Ulrich; Bang, Jeong Kyu; Lee, Kyung S
  3. Cell Cycle. 2020, Dec; 1-18.
  1. 6.   Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel
  2. Liu, F.; Park, J. E.; Qian, W. J.; Lim, D.; Graber, M.; Berg, T.; Yaffe, M. B.; Lee, K. S.; Burke, T. R.
  3. Nature Chemical Biology. 2011, Sep; 7(9): 595-601.
  1. 7.   Pharmacologic Modulation of Serine/Threonine Phosphorylation Highly Sensitizes PHEO in a MPC Cell and Mouse Model to Conventional Chemotherapy
  2. Martiniova, L.; Lu, J.; Chiang, J.; Bernardo, M.; Lonser, R.; Zhuang, Z. P.; Pacak, K.
  3. Plos One. 2011, Feb; 6(2): 8.
  1. 8.   Probing Binding Modes of Small Molecule Inhibitors to the Polo-Box Domain of Human Polo-like Kinase 1
  2. Liao, C. Z.; Park, J. E.; Bang, J. K.; Nicklaus, M. C.; Lee, K. S.
  3. Acs Medicinal Chemistry Letters. 2010, Jun; 1(3): 110-114.
  1. 9.   Phosphoproteornics for the discovery of kinases as cancer biornarkers and drug targets
  2. Yu, L. R.; Issaq, H. J.; Veenstra, T. D.
  3. Proteomics Clinical Applications. 2007, Sep; 1(9): 1042-1057.
  1. 11.   Polo-like kinase 1-mediated phosphorylation of the GTP-binding protein Ran is important for bipolar spindle formation
  2. Feng, Y.; Yuan, J. H.; Maloid, S. C.; Fisher, R.; Copeland, T. D.; Longo, D. L.; Conrads, T. P.; Veenstra, T. D.; Ferris, A.; Hughes, S.; Dimitrov, D. S.; Ferris, D. K.
  3. Biochemical and Biophysical Research Communications. 2006, Oct; 349(1): 144-152.
  1. 12.   Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase
  2. Liu, Y. S.; Shreder, K. R.; Gai, W. Z.; Corral, S.; Ferris, D. K.; Rosenblum, J. S.
  3. Chemistry & Biology. 2005, JAN; 12(1): 99-107.
  1. 13.   Caenorhabditis elegans contains a third Polo-like kinase gene
  2. Chase, D.; Golden, A.; Heidecker, G.; Ferris, D. K.
  3. DNA Sequence. 2000 11(3-4): 327-334.
  1. 14.   The Polo-like kinase PLK-1 is required for nuclear envelope breakdown and the completion of meiosis in Caenorhabditis elegans
  2. Chase, D.; Serafinas, C.; Ashcroft, N.; Kosinski, M.; Longo, D.; Ferris, D. K.; Golden, A.
  3. Genesis. 2000 26(1): 26-41.
  1. 15.   Expression and Phosphorylation of Fibroblast-Growth-Factor-Inducible Kinase (Fnk) During Cell-Cycle Progression
  2. Chase, D.; Feng, Y.; Hanshew, B.; Winkles, J. A.; Longo, D. L.; Ferris, D. K.
  3. Biochemical Journal. 1998 333(Part 3): 655-660.
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