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  1. 1.   Gene Co-Expression Network Analysis Associated with Endometrial Cancer Tumorigenesis and Survival Outcomes
  2. Clark, Alexis J; Singh, Rajesh; Leonis, Regina L; Stahlberg, Eric A; Clark, Zachary S; Lillard, James W
  3. International Journal of Molecular Sciences. 2024, Nov 18; 25(22):
  1. 2.   Analytical measuring interval, linearity, and precision of serology assays for detection of SARS-CoV-2 antibodies according to CLSI guidelines
  2. Haynesworth,Katrina; Kemp,Troy; Loftus,Sarah; Metz,Jordan; Castro, Nicholas C; Bullock, Jimmie; Fetterer, David; Pinto,Ligia
  3. mSphere. 2024, Oct 31; e0039324.
  1. 3.   The All of Us Research Program: Data quality, utility, and diversity
  2. Ramirez, Andrea H; Sulieman, Lina; Schlueter, David J; Halvorson, Alese; Qian, Jun; Ratsimbazafy, Francis; Loperena, Roxana; Mayo, Kelsey; Basford, Melissa; Deflaux, Nicole; Muthuraman, Karthik N; Natarajan, Karthik; Kho, Abel; Xu, Hua; Wilkins, Consuelo; Anton-Culver, Hoda; Boerwinkle, Eric; Cicek, Mine; Clark, Cheryl R; Cohn, Elizabeth; Ohno-Machado, Lucila; Schully, Sheri D; Ahmedani, Brian K; Argos, Maria; Cronin, Robert M; O'Donnell, Christopher; Fouad, Mona; Goldstein, David B; Greenland, Philip; Hebbring, Scott J; Karlson, Elizabeth W; Khatri, Parinda; Korf, Bruce; Smoller, Jordan W; Sodeke, Stephen; Wilbanks, John; Hentges, Justin; Mockrin,Stephen; Lunt, Christopher; Devaney, Stephanie A; Gebo, Kelly; Denny, Joshua C; Carroll, Robert J; Glazer, David; Harris, Paul A; Hripcsak, George; Philippakis, Anthony; Roden, Dan M
  3. Patterns (New York, N.Y.). 2022, Aug 12; 3(8): 100570.
  1. 4.   Aligning Tumor Mutational Burden (TMB) quantification across diagnostic platforms: Phase 2 of the Friends of Cancer Research TMB Harmonization Project
  2. Vega, Diana Merino; Yee, Laura M; McShane, Lisa M; Williams,Mickey; Chen,Li; Vilimas, Tomas; Fabrizio, David; Funari, Vincent; Newberg, Justin; Bruce, Lauryn Keeler; Chen, Shu-Jen; Baden, Jonathan; Barrett, J Carl; Beer, Philip; Butler, Matthew; Cheng, Jen-Hao; Conroy, Jeffrey; Cyanam, Dinesh; Eyring, Kenneth; Garcia, Elizabeth; Green, George; Gregersen, Vivi Raundahl; Hellmann, Matthew D; Keefer, Laurel A; Lasiter, Laura; Lazar, Alexander J; Li, Ming-Chung; Macconaill, Laura E; Meier, Kristen; Mellert, Hestia; Pabla, Sarabjot; Pallavajjalla, Aparna; Pestano, Gary; Salgado, Roberto; Samara, Raed; Sokol, Ethan S; Stafford, Phillip; Budczies, Jan; Stenzinger, Albrecht; Tom, Warren; Valkenburg, Kenneth C; Wang, XiaoZhe; Weigman, Victor; Xie, Mingchao; Xie, Qian; Zehir, Ahmet; Zhao, Chen; Zhao, Yingdong; Stewart, Mark D; Allen, Jeff
  3. Annals of oncology : official journal of the European Society for Medical Oncology. 2021, Dec; 32(12): 1626-1636.
  1. 5.   Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine
  2. Kaur, Gurmeet; Evans, David M.; Teicher, Beverly A.; Coussens,Nathan
  3. SLAS Discovery. 2021, Nov 12;
  1. 6.   A cross-study analysis of drug response prediction in cancer cell lines
  2. Xia, Fangfang; Allen, Jonathan; Balaprakash, Prasanna; Brettin, Thomas; Garcia-Cardona, Cristina; Clyde, Austin; Cohn, Judith; Doroshow,Jim; Duan, Xiaotian; Dubinkina, Veronika; Evrard,Yvonne; Fan, Ya Ju; Gans, Jason; He, Stewart; Lu,Pinyi; Maslov, Sergei; Partin, Alexander; Shukla, Maulik; Stahlberg,Eric; Wozniak, Justin M; Yoo, Hyunseung; Zaki,George; Zhu, Yitan; Stevens, Rick
  3. Briefings in Bioinformatics. 2021, Sep 14;
  1. 7.   Inhibition of Caspase-1 with Tetracycline Ameliorates Acute Lung Injury
  2. Peukert, Konrad; Fox, Mario; Schulz, Susanne; Feuerborn, Caroline; Frede, Stilla; Putensen, Christian; Wrigge, Hermann; Kummerer, Beate Mareike; David, Sascha; Seeliger, Benjamin; Welte, Tobias; Latz, Eicke; Klinman,Dennis; Wilhelm, Christoph; Steinhagen, Folkert; Bode, Christian
  3. American Journal of Respiratory and Critical Care Medicine. 2021, Jul 1; 204(1): 53-63.
  1. 8.   My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype
  2. Zhou, Yadi; Zhao, Junfei; Fang, Jiansong; Martin, William; Li, Lang; Nussinov,Ruth; Chan, Timothy A.; Eng, Charis; Cheng, Feixiong
  3. Genome Biology. 2021, Jan 29; 22(1):
  1. 9.   Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment
  2. Wheeler, David A; Takebe, Naoko; Hinoue, Toshinori; Hoadley, Katherine A; Cardenas, Maria F; Hamilton, Alina M; Laird, Peter W; Wang, Linghua; Johnson, Adrienne; Dewal, Ninad; Miller, Vincent; Piñeyro, David; Castro de Moura, Manuel; Esteller, Manel; Shen, Hui; Zenklusen, Jean Claude; Tarnuzzer, Roy; McShane, Lisa M; Tricoli, James V; Williams, Paul M; Lubensky, Irina; O'Sullivan-Coyne, Geraldine; Kohn, Elise C; Little, Richard F; White, Jeffrey; Malik, Shakun; Harris, Lyndsay; Weil, Carol; Chen, Alice P; Karlovich,Chris; Rodgers, Brian; Shankar, Lalitha; Jacobs, Paula; Nolan, Tracy; Hu, Jianhong; Muzny, Donna M; Doddapaneni, Harshavardhan; Korchina, Viktoriya; Gastier-Foster, Julie; Bowen, Jay; Leraas, Kristen; Edmondson,Elijah; Doroshow, James H; Conley, Barbara A; Ivy, S Percy; Staudt, Louis M
  3. Cancer Cell. 2021, Jan 11; 39(1): 38-53.e7.
  1. 10.   Enhanced Co-Expression Extrapolation (COXEN) Gene Selection Method for Building Anti-Cancer Drug Response Prediction Models
  2. Zhu, Yitan; Brettin, Thomas; Evrard,Yvonne; Xia, Fangfang; Partin, Alexander; Shukla, Maulik; Yoo, Hyunseung; Doroshow, James H; Stevens, Rick L
  3. Genes. 2020, Sep 11; 11(9): pii: E1070.
  1. 11.   Immunotherapy in sepsis - brake or accelerate?
  2. Steinhagen, Folkert; Schmidt, Susanne; Schewe, Jens-Christian; Peukert, Konrad; Klinman,Dennis; Bode, Christian
  3. Pharmacology & therapeutics. 2020, APR; 208
  1. 12.   Patient-derived orthotopic xenograft models of sarcoma
  2. Igarashi, Kentaro; Kawaguchi, Kei; Murakami, Takashi; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Hiroshima, Yukihiko; Higuchi, Takashi; Oshiro, Hiromichi; Nelson, Scott D; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer letters. 2020, Jan 28; 469: 332-339.
  1. 13.   Autoinhibition can identify rare driver mutations and advise pharmacology
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020, Jan; 34(1): 16-29.
  1. 14.   Why Are Some Driver Mutations Rare?
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. Trends in pharmacological sciences. 2019, Dec; 40(12): 919-929.
  1. 15.   Combing the Cancer Genome for Novel Kinase Drivers and New Therapeutic Targets
  2. Torres-Ayuso,Pedro; Brognard,John
  3. CANCERS. 2019, Dec; 11(12):
  1. 16.   AI Meets Exascale Computing: Advancing Cancer Research With Large-Scale High Performance Computing
  2. Bhattacharya, Tanmoy; Brettin, Thomas; Doroshow, James H.; Evrard,Yvonne; Greenspan, Emily J.; Gryshuk, Amy L.; Hoang, Thuc T.; Lauzon, Carolyn B. Vea; Nissley,Dwight; Penberthy, Lynne; Stahlberg,Eric; Stevens, Rick; Streitz, Fred; Tourassi, Georgia; Xia, Fangfang; Zaki,George
  3. Frontiers in oncology. 2019, Oct 2; 9
  1. 17.   Eribulin Suppressed Cisplatinum- and Doxorubicin-resistant Recurrent Lung Metastatic Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Kiyuna, Tasuku; Tome, Yasunori; Miyake, Kentaro; Murakami, Takashi; Oshiro, Hiromichi; Igarashi, Kentaro; Kawaguchi, Kei; Hsu, John; Singh, Manish; Li, Yunfeng; Nelson, Scott; Bouvet, Michael; Singh,Shree Ram; Kanaya, Fuminori; Hoffman, Robert M
  3. Anticancer research. 2019, Sep; 39(9): 4775-4779.
  1. 18.   Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model
  2. Igarashi, Kentaro; Kawaguchi, Kei; Kiyuna, Tasuku; Miyake, Kentaro; Miyake, Masuyo; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Higuchi, Takashi; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Tissue & cell. 2019, Jun; 58: 107-111.
  1. 19.   A patient-derived orthotopic xenograft (PDOX) nude-mouse model precisely identifies effective and ineffective therapies for recurrent leiomyosarcoma
  2. Zhang, Zhiying; Hu, Kaiwen; Kiyuna, Tasuko; Miyake, Kentaro; Kawaguchi, Kei; Igarashi, Kentaro; Nelson, Scott D; Li, Yunfeng; Singh, Shree Ram; Hoffman, Robert M
  3. Pharmacological research. 2019, Apr; 142: 169-175.
  1. 20.   Clinical Applications of Next-Generation Sequencing in Precision Oncology
  2. Karlovich,Chris; Williams,Mickey
  3. Cancer journal (Sudbury, Mass.). 2019, Jul/Aug; 25(4): 264-271.
  1. 21.   Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma
  2. Kawaguchi, Kei; Higuchi, Takashi; Li, Shukuan; Han, Qinghong; Tan, Yuying; Igarashi, Kentaro; Zhao, Ming; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Ohshiro, Hiromichi; Sugisawa, Norihiko; Zhang, Zhiying; Razmjooei, Sahar; Wangsiricharoen, Sintawat; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Eckardt, Mark A; Singh, Arun S; Singh, Shree Ram; Eilber, Fritz C; Unno, Michiaki; Hoffman, Robert M
  3. Biochemical and Biophysical Research Communications. 2018, Sep 18; 503(4): 3086-3092.
  1. 22.   Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model
  2. Kiyuna, Tasuku; Tome, Yasunori; Murakami, Takashi; Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Miyake, Masuyo; Li, Yunfeng; Nelson, Scott D; Dry, Sarah M; Singh, Arun S; Russell, Tara A; Elliott, Irmina; Singh, Shree Ram; Kanaya, Fuminori; Eilber, Fritz C; Hoffman, Robert M
  3. BMC cancer. 2018, Aug 20; 18(1): 840.
  1. 23.   Patterns of Sensitivity to a Panel of Drugs are highly Individualized for Undifferentiated/Unclassified Soft Tissue Sarcoma (USTS) in Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Models
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Singh, Arun S; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Unno, Michiaki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Journal of drug targeting. 2018, Jul 19; 1-25.
  1. 24.   MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Lwin, Thinzar M; Miyake, Masuyo; Kiyuna, Tasuku; Hwang, Ho Kyoung; Murakami, Takashi; Delong, Jonathan C; Singh, Shree Ram; Clary, Bryan; Bouvet, Michael; Unno, Michiaki; Hoffman, Robert M
  3. Tissue & cell. 2018, Jun; 52: 124-128.
  1. 25.   Recombinant methioninase in combination with DOX overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma
  2. Igarashi, Kentaro; Kawaguchi, Kei; Li, Shukuan; Han, Qinghong; Tan, Yuying; Murakami, Takashi; Kiyuna, Tasuku; Miyake, Kentaro; Miyake, Masuyo; Singh, Arun S; Eckhardt, Mark A; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Tsuchiya, Hiroyuki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Cancer Letters. 2018, MAR 28; 417: 168-173.
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