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  1. 1.   Two hearts beat as one: the debate over RAS dimers continues
  2. Stephen,Andy
  3. Trends in Biochemical Sciences. 2024, Nov; 49(11): 933-935.
  1. 2.   Regulation of RAF family kinases: new insights from recent structural and biochemical studies
  2. Spencer-Smith, Russell; Morrison,Deborah
  3. Biochemical Society Transactions. 2024, June 26; 52(3): 1061-1069.
  1. 3.   Phase II study of vemurafenib in children and young adults with tumors harboring BRAF V600 mutations: NCI-COG pediatric MATCH trial (APEC1621) Arm G
  2. Nelson, Marie V; Kim, AeRang; Williams,Mickey; Roy-Chowdhuri, Sinchita; Patton, David R; Coffey, Brent D; Reid, Joel M; Piao, Jin; Saguilig, Lauren; Alonzo, Todd A; Berg, Stacey L; Ramirez, Nilsa C; Jaju, Alok; Fox, Elizabeth; Weigel, Brenda J; Hawkins, Douglas S; Mooney, Margaret M; Takebe, Naoko; Tricoli, James V; Janeway, Katherine A; Seibel, Nita L; Parsons, D Williams
  3. The Oncologist. 2024, Jun 14;
  1. 4.   RAS and SHOC2 Roles in RAF Activation and Therapeutic Considerations
  2. Bonsor,Daniel; Simanshu,Dhirendra
  3. Annual Review of Cancer Biology. 2024, Jun; 8: 97-113.
  1. 5.   Ex vivo culture resting time impacts transplantation outcomes of genome-edited human hematopoietic stem and progenitor cells in xenograft mouse models
  2. Demirci, Selami; Khan,Muhammad; Hinojosa, Gabriela; Le, Anh; Leonard, Alexis; Essawi, Khaled; Gudmundsdottir, Bjorg; Liu, Xiong; Zeng, Jing; Inam, Zaina; Chu, Rebecca; Uchida, Naoya; Araki, Daisuke; London, Evan; Butt, Henna; Maitland, Stacy A; Bauer, Daniel E; Wolfe, Scot A; Larochelle, Andre; Tisdale, John F
  3. Cytotherapy. 2024, Jun ; 26(6): 641-648.
  1. 6.   Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier
  2. Thomas, Joanna R; Frye, William J E; Robey, Robert W; Warner,Andrew; Butcher,Donna; Matta,Jennifer; Morgan,Tamara; Edmondson,Elijah; Salazar, Paula B; Ambudkar, Suresh V; Gottesman, Michael M
  3. Fluids and Barriers of the CNS. 2024, Mar 15; 21(1): 27.
  1. 7.   Structure Guided Design, Synthesis, and Biological Evaluation of Oxetane-Containing Indole Analogues
  2. Ren, Wen; Vairin, Rebecca; Ward, Jacob D; Francis, Ricardo; VanNatta, Jenny; Bai,Ruoli; Tankoano, Pouguiniseli E; Deng, Yuling; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G
  3. Bioorganic & Medicinal Chemistry. 2023, Jun 29; 92: 117400.
  1. 8.   Structural insights into the role of SHOC2-MRAS-PP1C complex in RAF activation
  2. Bonsor,Daniel; Simanshu,Dhirendra
  3. The FEBS Journal. 2023, Apr 19;
  1. 9.   Creation and preclinical evaluation of a novel mussel-inspired, biomimetic, bioactive bone graft scaffold: direct comparison with Infuse bone graft using a rat model of spinal fusion
  2. Cottrill, Ethan; Pennington, Zach; Wolf,Matthew; Dirckx, Naomi; Ehresman, Jeff; Perdomo-Pantoja, Alexander; Rajkovic, Christian; Lin, Jessica; Maestas, David R; Mageau, Ashlie; Lambrechts, Dennis; Stewart, Veronica; Sciubba, Daniel M; Theodore, Nicholas; Elisseeff, Jennifer H; Witham, Timothy
  3. Journal of Neurosurgery. Spine. 2023, Mar 31; 39(1): 113-121.
  1. 10.   RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation
  2. Smith,Russell; Terrell,Elizabeth; Insinna, Christine; Agamasu, Constance; Wagner, Morgan E; Ritt,Daniel; Stauffer,Jimmy; Stephen,Andy; Morrison,Deborah
  3. Molecular Cell. 2022, Nov 17; 82(22): 4262-4276.
  1. 11.   ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
  2. Su, Wenjing; Mukherjee, Radha; Yaeger, Rona; Son, Jieun; Xu, Jianing; Na, Na; Merna Timaul, Neilawattie; Hechtman, Jaclyn; Paroder, Viktoriya; Lin, Mika; Mattar, Marissa; Qiu, Juan; Chang, Qing; Zhao, Huiyong; Zhang, Jonathan; Little, Megan; Adachi, Yuta; Han, Sae-Won; Taylor, Barry S; Ebi, Hiromichi; Abdel-Wahab, Omar; de Stanchina, Elisa; Rudin, Charles M; Jänne, Pasi A; McCormick, Frank; Yao, Zhan; Rosen, Neal
  3. Molecular Cell. 2022, May 14;
  1. 12.   Are We Making PROGRESS in Preventing Graft-versus-Host Disease and Improving Clinical Outcomes? Impact of BMT CTN 1301 Study Results on Clinical Practice
  2. Hamilton, Betty K; Cutler, Corey; Divine, Clint; Juckett, Mark; LeMaistre, Charles; Stewart, Susan; Wilder, Jennifer; Horowitz, Mary; Khera, Nandita; Burns, Linda J
  3. Transplantation and Cellular Therapy. 2022, May 09;
  1. 13.   CT-707 overcomes hypoxia-mediated sorafenib resistance in Hepatocellular carcinoma by inhibiting YAP signaling
  2. Chen,Zibo; Yuan, Tao; Yan, Fangjie; Ye, Song; Xie, Qin; Zhang, Bo; Lin, Nengmin; He, Qiaojun; Yang, Bo; Zhu, Hong
  3. BMC Cancer. 2022, Apr 19; 22(1): 425.
  1. 14.   Regulation of GTPase function by autophosphorylation
  2. Johnson, Christian W; Seo, Hyuk-Soo; Terrell,Elizabeth; Yang, Moon-Hee; KleinJan, Fenneke; Gebregiworgis, Teklab; Gasmi-Seabrook, Genevieve M C; Geffken, Ezekiel A; Lakhani, Jimit; Song, Kijun; Bashyal, Puspalata; Popow, Olesja; Paulo, Joao A; Liu, Andrea; Mattos, Carla; Marshall, Christopher B; Ikura, Mitsuhiko; Morrison, Deborah K; Dhe-Paganon, Sirano; Haigis, Kevin M
  3. Molecular Cell. 2022, Feb 18; 82(5): 950-968.e14.
  1. 15.   Classical RAS proteins are not essential for paradoxical ERK activation induced by RAF inhibitors
  2. Lai, Lick Pui; Fer,Nicole; Burgan,William; Wall,Vanessa; Xu,Bingfang; Soppet,Daniel; Esposito,Dom; Nissley,Dwight; McCormick, Frank
  3. Proceedings of the National Academy of Sciences of the United States of America. 2022, Feb 01; 119(5):
  1. 16.   The mechanism of Raf activation through dimerization
  2. Zhang,Mingzhen; Maloney,Ryan; Jang,Hyunbum; Nussinov,Ruth
  3. Chemical Science. 2021, Dec 08; 12(47): 15609-15619.
  1. 17.   Embryonic hyperglycemia perturbs the development of specific retinal cell types, including photoreceptors
  2. Titialii-Torres,Kayla; Morris, Ann C
  3. Journal of Cell Science. 2021, Dec 1;
  1. 18.   Myelination induces axonal hotspots of synaptic vesicle fusion that promote sheath growth
  2. Almeida, Rafael G; Williamson, Jill M; Madden, Megan E; Early, Jason J; Voas,Matthew; Talbot, William S; Bianco, Isaac H; Lyons, David A
  3. Current biology : CB. 2021, Sep 13; 31(17): 3743-3754.e5.
  1. 19.   Leucine zipper transcription factor-like 1 (LZTFL1), an intraflagellar transporter protein 27 (IFT27) associated protein, is required for normal sperm function and male fertility
  2. Huang, Qian; Li, Wei; Zhou, Qi; Awasthi,Roackie; Cazin, Caroline; Yap, Yitian; Mladenovic-Lucas, Ljiljana; Hu, Bo; Jeyasuria, Pancharatnam; Zhang, Ling; Granneman, James G.; Hess, Rex A.; Ray, Pierre F.; Kherraf, Zine-Eddine; Natarajan,Ven; Zhang, Zhibing
  3. Developmental biology. 2021, Sep; 477: 164-176.
  1. 20.   B-Raf autoinhibition in the presence and absence of 14-3-3
  2. Zhang,Mingzhen; Jang,Hyunbum; Li, Zhigang; Sacks, David B.; Nussinov,Ruth
  3. Structure. 2021, Jul 1; 29(7): 768-777.e2.
  1. 21.   TPM, FPKM, or Normalized Counts? A Comparative Study of Quantification Measures for the Analysis of RNA-seq Data from the NCI Patient-Derived Models Repository
  2. Zhao, Yingdong; Li, Ming-Chung; Konaté, Mariam M; Chen,Li; Das,Biswajit; Karlovich,Chris; Williams,Mickey; Evrard,Yvonne; Doroshow, James H; McShane, Lisa M
  3. Journal of translational medicine. 2021, Jun 22; 19(1): 269.
  1. 22.   Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody
  2. Lee, Myungeun; Lu, Zhi Hong; Shoemaker, Charles B.; Tremblay, Jacqueline M.; St Croix,Brad; Seaman,Steven; Gonzalez-Pastor, Rebeca; Kashentseva, Elena A.; Dmitriev, Igor P.; Curiel, David T.
  3. Journal of Controlled Release : Official Journal of the Controlled Release Society. 2021, Jun 10; 334: 106-113.
  1. 23.   The mechanism of activation of monomeric B-Raf V600E
  2. Maloney,Ryan; Zhang,Mingzhen; Jang,Hyunbum; Nussinov,Ruth
  3. Computational and structural biotechnology journal. 2021, Jun 4; 19: 3349-3363.
  1. 24.   TET2 and DNMT3A mutations and exceptional response to 4'-thio-2'-deoxycytidine in human solid tumor models
  2. Yang, Sherry X; Hollingshead, Melinda; Rubinstein, Larry; Nguyen, Dat; Larenjeira, Angelo B A; Kinders,Robert; Difilippantonio, Michael; Doroshow, James H
  3. Journal of Hematology & Oncology. 2021, May 26; 14(1):
  1. 25.   Impact of Preanalytical Factors on the Measurement of Tumor Tissue Biomarkers Using Immunohistochemistry
  2. Bagchi, Aditi; Madaj, Zachary; Engel, Kelly B; Guan, Ping; Rohrer, Daniel C; Valley, Dana R; Wolfrum, Emily; Feenstra, Kristin; Roche,Nancy; Hostetter, Galen; Moore, Helen M; Jewell, Scott D
  3. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2021, May; 69(5): 297-320.
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