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  1. 1.   In-utero exposure to zidovudine-containing antiretroviral therapy and clonal hematopoiesis in HIV-exposed uninfected newborns
  2. Lin, Shu-Hong; Wang, Youjin; Hartley, Stephen W.; Karyadi, Danielle M.; Lee, Olivia W.; Zhu, Bin; Zhou,Weiyin; Brown, Derek W.; Beilstein-Wedel, Erin; Hazra, Rohan; Kacanek, Deborah; Chadwick, Ellen G.; Marsit, Carmen J.; Poirier, Miriam C.; Brummel, Sean S.; Chanock, Stephen J.; Engels, Eric A.; Machiela, Mitchell J.
  3. AIDS. 2021, Aug 1; 35(10): 1525-1535.
  1. 2.   Structural studies of series HIV-1 nonnucleoside reverse transcriptase inhibitors 1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)-benzimidazoles with different 4-substituents
  2. Ziolkowska, N. E.; Michejda, C. J.; Bujacz, G. D.
  3. Journal of Molecular Structure. 2010, Mar; 966(1-3): 53-58.
  1. 3.   Structure of HIV-1 nonnucleoside reverse transcriptase inhibitors derivatives of N-benzyl-benzimidazole with different substituents in position 4
  2. Ziolkowska, N. E.; Michejda, C. J.; Bujacz, G. D.
  3. Journal of Molecular Structure. 2010, Jan; 963(2-3): 188-193.
  1. 4.   Crystal structures of HIV-1 nonnucleoside reverse transcriptase inhibitors: N-benzyl-4-methyl-benzimidazoles
  2. Ziolkowska, N. E.; Michejda, C. J.; Bujacz, G. D.
  3. Journal of Molecular Structure. 2009 930(1-3): 157-161.
  1. 5.   Structural investigation of HIV-1 nonnucleoside reverse transcriptase inhibitors: 2-Aryl-substituted benzimidazoles
  2. Ziolkowska, N. E.; Michejda, C. J.; Bujacz, G. D.
  3. Journal of Molecular Structure. 2009 937(1-3): 34-38.
  1. 6.   Synthesis of conformationally locked carbocyclic nucleoside phosphonates to probe the active site of HIV-1 RT
  2. Saneyoshi, H.; Vu, B. C.; Hughes, S. H.; Boyer, P. L.; Sarafianos, S. G.; Marquez, V. E.
  3. Nucleic acids symposium series (2004). 2008 (52): 623-4.
  1. 7.   Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT
  2. Nissley, D. V.; Radzio, J.; Ambrose, Z.; Sheen, C. W.; Hamamouch, N.; Moore, K. L.; Tachedjian, G.; Sluis-Cremer, N.
  3. Biochemical Journal. 2007, May; 404: 151-157.
  1. 8.   New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: Synthesis, resolution, and inhibitory activity
  2. Krajewski, K.; Zhang, Y. J.; Parrish, D.; Deschamps, J.; Roller, P. P.; Pathak, V. K.
  3. Bioorganic & Medicinal Chemistry Letters. 2006, Jun; 16(11): 3034-3038.
  1. 9.   Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy
  2. Palmer, S.; Boltz, V.; Maldarelli, F.; Kearney, M.; Halvas, E. K.; Rock, D.; Falloon, J.; Davey, R. T.; Dewar, R. L.; Metcalf, J. A.; Mellors, J. W.; Coffin, J. M.
  3. Aids. 2006, Mar; 20(5): 701-710.
  1. 10.   Crystallography and the design of anti-AIDS drugs: Conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors
  2. Das, K.; Lewi, P. J.; Hughes, S. H.; Arnold, E.
  3. Progress in Biophysics and Molecular Biology. 2005, JUN; 88(2): 209-231.
  1. 11.   Panel of prototypical infectious molecular HIV-1 clones containing multiple nucleoside reverse transcriptase inhibitor resistance mutations
  2. Johnston, E.; Dupnik, K. M.; Gonzales, M. J.; Winters, M. A.; Rhee, S. Y.; Imamichi, T.; Shafer, R. W.
  3. Aids. 2005, APR 29; 19(7): 731-733.
  1. 12.   Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: Balance between RNase H activity and nucleotide excision
  2. Nikolenko, G. N.; Palmer, S.; Maldarelli, F.; Mellors, J. W.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, FEB 8; 102(6): 2093-2098.
  1. 13.   In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques
  2. Ambrose, Z.; Boltz, V.; Palmer, S.; Coffin, J. M.; Hughes, S. H.; KewalRamani, V. N.
  3. Journal of Virology. 2004, DEC; 78(24): 13553-13561.
  1. 14.   Mutations in HIV-1 RNase H domain confer high-level resistance to nucleoside reverse transcriptase inhibitors and provide novel insights into the mechanism of nucleotide excision-mediated drug resistance
  2. Nikolenko, G. N.; Palmer, S.; Maldarelli, F.; Mellors, J. W.; Coffin, J. M.; Pathak, V. K.
  3. Antiviral Therapy. 2004, AUG; 9(4): U35-U36.
  1. 15.   Action of Anti-HIV drugs and resistance: Reverse transcriptase inhibitors and protease inhibitors
  2. Imamichi, T.
  3. Current Pharmaceutical Design. 2004 10(32): 4039-4053.
  1. 16.   Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants
  2. Das, K.; Clark, A. D.; Lewi, P. J.; Heeres, J.; de Jonge, M. R.; Koymans, L. M. H.; Vinkers, H. M.; Daeyaert, F.; Ludovici, D. W.; Kukla, M. J.; De Corte, B.; Kavash, R. W.; Ho, C. Y.; Ye, H.; Lichtenstein, M. A.; Andries, K.; Pauwels, R.; de Bethune, M. P.; Boyer, P. L.; Clark, P.; Hughes, S. H.; Janssen, P. A. J.; Arnold, E.
  3. Journal of Medicinal Chemistry. 2004 47(10): 2550-2560.
  1. 17.   Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
  2. Tuske, S.; Sarafianos, S. G.; Clark, A. D.; Ding, J. P.; Naeger, L. K.; White, K. L.; Miller, M. D.; Gibbs, C. S.; Boyer, P. L.; Clark, P.; Wang, G.; Gaffney, B. L.; Jones, R. A.; Jerina, D. M.; Hughes, S. H.; Arnold, E.
  3. Nature Structural & Molecular Biology. 2004 11(5): 469-474.
  1. 18.   Structural and biochemical mechanisms of HIV-1 RT drug resistance
  2. Boyer, P. L.; Gao, H. Q.; Serafianos, S.; Ding, J.; Clark, P.; Clark, A.; Arnold, E.; Hughes, S. H.
  3. Conference on Retroviruses and Opportunistic Infections. 1999, 218 (abstract no. S33).
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